Researchers in the Duke Division of Pulmonary, Allergy, and Critical Care Medicine are pursuing a number of miscellaneous clinical trials in order to understand the mechanisms of a variety of lung diseases.
Current Clinical Trials
Select a trial below to read the full description on the clinicaltrials.gov Web site:
Lung Mucus Hypersecretion and NQO1: The research plan proposes translational studies in relevant animal models and human subjects in order to identify host (genetic) susceptibility factors that confer vulnerability to the prototypal air pollutant, ozone. The results will have significant impact upon, and aid in, understanding mechanisms regulating pro-oxidant lung injury, production and secretion of airway mucins, and clearance of respiratory mucus, and adverse health effects, that occur during and following exposure to airborne respiratory irritants.
Investigators: W. Michael Foster, PhD and John Hollingsworth, MD
Novel Influenza A (H1N1) Surveillance Registry: The purpose of this surveillance registry is to characterize the demographics, clinical features, outcomes, and resource utilization of patients with H1N1 influenza infection who require intensive care.
Principal Investigator: Neil MacIntyre, MD
Protocolized Care for Early Septic Shock (ProCESS): The ProCESS study is large, 5-year, multi-center study of alternative resuscitation strategies for septic shock. The study hypothesizes that there are "golden hours" in the initial management of septic shock where prompt, rigorous, standardized care can improve clinical outcomes.
Sub-Investigator: Joseph Govert, MD
Enroll in a Pulmonary Clinical Trial at Duke
Researchers in our division are investigating a variety of treatments and therapies to respond to lung disease. Click here for a list of current clinical trials.