Laura Musselwhite, MD, MPH

Start Year
2016

Education and Training

College/University
University of North Carolina at Chapel Hill

Additional training
MPH, Johns Hopkins University, 2011

Medical School
Duke University

Residency
Duke University - Global Health Pathway

Career and Research Goals

The purpose of my work is to improve cancer care delivery and patient outcomes (e.g., early detection of disease, cancer recurrence, and survival). The overall theme of my research is to understand interactions between determinants of cancer risk and to improve upon their combined effect on cancer stage at diagnosis and survival. I have developed a specific research focus on designing population-based strategies to improve the early detection of gastrointestinal and cervical cancers, for which the global burden of disease is high, and the need for scalable, cost-conscious tools for health systems exists..

Honors, awards and distinctions

Grants

  • Gates Foundation Grand Challenges Explorations Grant
  • Duke Global Cancer Pilot Grant

Awards

  • Induction into Robert J. Lefkowitz Society, 2017
  • N.I.H. Fogarty Global Health Fellowship, 2015-2016
  • Califf Medicine Resident Research Award, Department of Medicine, Duke University, 2015
  • Feagin Leadership Scholar, Duke University Medical Center, 2015
  • Califf Medicine Resident Research Award, Department of Medicine, Duke University, 2014
  • Appleseed Teaching Award, awarded by medical students for teaching excellence, Duke University School of Medicine, 2013
  • Senior Scholarship, awarded by medical school Deans for academic excellence, Duke University School of Medicine, 2012
  • Global Health Scholarship, merit-based, full tuition, Johns Hopkins University, 2011
  • N.I.H. Clinical Research Training Program, 2010

Recent Abstracts

  • Musselwhite, L, Thomas, C, Abbott, D, Hauser, E, Wagner, L, Morris, S, Weiss, D, Lieberman, D, and Provenzale, D. Risk factors for interval advanced colorectal neoplasia after screening colonoscopy. American Society of Clinical Oncology Annual Meeting; Chicago, IL. May 2015.
  • Musselwhite, LW, Schroeder, K, Bhattacharya, M, Vanderburg, SB, Masalu, NA, Chandy, M, Mauad, E, Bartlett, J, Kastan, MB, Merson, M, Chao, NJ. Duke University Global Cancer Program: A multidisciplinary approach to partnerships in global cancer care. American Society of Clinical Oncology Annual Meeting; Chicago, IL. May 2015. 
  • Hauser, E, Musselwhite, L, McNeill, R, Abbott, D, Thomas, C, O’Leary, M, Andrews, SM Wagner, L, Gellad, ZF, Weiss, DG, Lieberman, DT, Provenzale, D. Interactions of family history with baseline risk factors at 5-year follow-up in a CRC screening study of U.S. Veterans. American Society of Human Genetics Annual Meeting; Baltimore, MD. October 2015.
  • Lieberman, D, Abbott, DH, O’Leary, MC, Hauser, ER, Williams, C, McNeill, RB, Sullivan, B, Musselwhite, L, Weiss, D, Gellad, ZF, Provenzale, D. Clinical risk group at baseline is associated with 10-year outcomes in a screening cohort-longitudinal analysis of the CSP 380 cohort. Digestive Disease Week. San Diego, CA. May 2016.
  • Musselwhite, LW, Abbott, D, O’Leary, MC, Hauser, ER, McNeil, RB, Weiss, D, Lieberman, D, and Provenzale, D. Risk factors for interval advanced colorectal neoplasia after screening colonoscopy: 10-year follow-up of a prospective, multi-center cohort in the United States. 50th Anniversary International Agency for Research on Cancer Conference, Lyon, France. June 2016.
  • Kwaramba, T*, Musselwhite, LW*, Mariano, VS, Pantano, N, Hosokawa, T, Hauser, E, Smith, JS, Hoyo, C, Vazquez, FL, Longatto-Filho, A, Murphy, SK, Reis, RM, Mauad, EC, Possati-Resende, JC, and Fregnani, JH. Racial disparities in Human Papillomavirus types 16/18 in women with abnormal cytology in a prospective, cross-sectional study in Brazil. Global Partnerships to Advance NCD Research within the Sustainable Development Goal Agenda Conference, Atlanta, GA. August 2016. *Authors contributed equally
  • Sullivan, B, Qin, X, Sims, K, O’Leary, M, Bullard, J, Hauser, E, McNeil, R, Musselwhite, L, Gellad, Z, Williams, C, Weiss, D, Lieberman, D, Provenzale, D. Risk factors in Veterans with and without adenoma multiplicity in a screening cohort. Digestive Disease Week. Chicago, IL. May 2017.
  • Musselwhite, LW, Redding, TS, Sims, KJ, O’Leary, M, Hauser, ER, Hyslop, T, Lieberman, DA, Provenzale, DT. Validation of the NCI colorectal cancer risk assessment tool in the CSP 380 Veterans cohort. ASCO annual meeting. Chicago, IL. June 2017.
  • Oliveira, CM, Musselwhite, LW, Pantano, N, Vazquez, FL, Ramos, K, Smith, JS, Kernen,, P, Belmares, M, Schweizer, J, Lu, P, Souza, P, Tesoni, S, Possati-Resende, J, Vieira, M, Reis, R, Cintra, G, Andrade, C, Longatto-Filho, A, Fregnani, JH. Is HPV E6 oncoprotein detectable in urine among women with invasive cervical cancer? EUROGIN. Amsterdam, NE. October 2017.
  • Musselwhite, LW, Kwaramba, T, Pantano, N, Tesoni SC, Hosokawa, TT, Longatto-Filho, A, Possati-Resende, JC, Vazquez, FL, Mauad, EC, Fregnani, JH, Brewer, NT, Smith, JS. HPV vaccine acceptability for daughters among at-risk women in Brazil. EUROGIN. Amsterdam, NE. October 2017.
  • Qin, X, Hauser, ER, Stone, A, Carter, WC, Sims, K, Whitley, RL, Humphries, D, O’Leary, MC, Redding, TS, Sullivan, B, Gellad, ZF, Musselwhite, LW, Provenzale, D, Lieberman, D. Genetic association analysis of advanced neoplasia in a colon cancer screening cohort. Digestive Disease Week. Washington D.C. May 2018.

Publications

Manion, Maura, Bruno B. Andrade, Rebecca DerSimonian, Wenjuan Gu, Adam Rupert, Laura W. Musselwhite, Juan G. Sierra-Madero, et al. “Country of residence is associated with distinct inflammatory biomarker signatures in HIV-infected patients..” Journal of Virus Eradication 3, no. 1 (January 2017): 24–33.

PMID
28275455
Scholars@Duke

Musselwhite, Laura W., Bruno B. Andrade, Susan S. Ellenberg, Ann Tierney, Pablo F. Belaunzaran-Zamudio, Adam Rupert, Michael M. Lederman, Ian Sanne, Juan G. Sierra Madero, and Irini Sereti. “Vitamin D, D-dimer, Interferon γ, and sCD14 Levels are Independently Associated with Immune Reconstitution Inflammatory Syndrome: A Prospective, International Study..” Ebiomedicine 4 (February 2016): 115–23. https://doi.org/10.1016/j.ebiom.2016.01.016.

PMID
26981576
Full Text

Musselwhite, Laura W., Cristina M. Oliveira, Tendai Kwaramba, Naitielle de Paula Pantano, Jennifer S. Smith, José Humberto Fregnani, Rui M. Reis, Edmundo Mauad, Fabiana de Lima Vazquez, and Adhemar Longatto-Filho. “Racial/Ethnic Disparities in Cervical Cancer Screening and Outcomes..” Acta Cytologica 60, no. 6 (January 2016): 518–26. https://doi.org/10.1159/000452240.

PMID
27825171
Full Text

Vidal, Adriana C., David Skaar, Rachel Maguire, Seyram Dodor, Laura W. Musselwhite, John A. Bartlett, Olola Oneko, et al. “IL-10, IL-15, IL-17, and GMCSF levels in cervical cancer tissue of Tanzanian women infected with HPV16/18 vs. non-HPV16/18 genotypes..” Infect Agent Cancer 10 (2015). https://doi.org/10.1186/s13027-015-0005-1.

PMID
25810759
Full Text

Funderburg, Nicholas T., David A. Zidar, Carey Shive, Anthony Lioi, Joseph Mudd, Laura W. Musselwhite, Daniel I. Simon, et al. “Shared monocyte subset phenotypes in HIV-1 infection and in uninfected subjects with acute coronary syndrome..” Blood 120, no. 23 (November 2012): 4599–4608. https://doi.org/10.1182/blood-2012-05-433946.

PMID
23065151
Full Text

Hotez, Peter J., Eric Dumonteil, Laila Woc-Colburn, Jose A. Serpa, Sarah Bezek, Morven S. Edwards, Camden J. Hallmark, Laura W. Musselwhite, Benjamin J. Flink, and Maria Elena Bottazzi. “Chagas disease: "the new HIV/AIDS of the Americas"..” Plos Neglected Tropical Diseases 6, no. 5 (January 2012). https://doi.org/10.1371/journal.pntd.0001498.

PMID
22666504
Full Text

Musselwhite, Laura W., Karolina Maciag, Alex Lankowski, Michael C. Gretes, Thomas E. Wellems, Gloria Tavera, Rebecca E. Goulding, and Ethan Guillen. “First Universities Allied for Essential Medicines (UAEM) Neglected Diseases and Innovation Symposium..” In The American Journal of Tropical Medicine and Hygiene, 86:65–74, 2012. https://doi.org/10.4269/ajtmh.2012.11-0608.

PMID
22232453
Full Text

Musselwhite, Laura W., Virginia Sheikh, Thomas D. Norton, Adam Rupert, Brian O. Porter, Scott R. Penzak, Jeff Skinner, JoAnn M. Mican, Colleen Hadigan, and Irini Sereti. “Markers of endothelial dysfunction, coagulation and tissue fibrosis independently predict venous thromboembolism in HIV.” Aids 25, no. 6 (March 2011): 787–95. https://doi.org/10.1097/qad.0b013e3283453fcb.

Full Text

Pages