Ryan Duffy, MD

Start Year


Apex, NC

Where did you attend college/university?
Appalachian State University

Where did you attend medical school?
Virginia Tech

What are your career goals?
​I'd like to stay in academic medicine and find a position where I can balance patient care with clinical research and medical education. 

What did you do the summer before Intern year?
Did some traveling, moved to Durham, then got married!

"Duke is strong all around, but I would say the biggest strength here is the learning environment. Faculty are passionate about teaching and the residents are excited to learn."

-Ryan Duffy

Reflections on the Duke Program

What were you looking for in a residency program?
When I was interviewing I was looking for a strong program with research support, happy residents, and located in a city where I could afford to live. Duke was an obvious choice for me at the end of interview season.

What are the strengths of the Duke Program?
Duke is strong all around, but I would say the biggest strength here is the learning environment. Faculty are passionate about teaching and the residents are excited to learn. It's also been really cool to go in to the hospital each day and work with world-class faculty who choose to spend their time teaching me.

What are you observations about the relationship between faculty and house staff?
Faculty here are great. They’ve all been very respectful and available to house staff. It’s been great to get to know a lot of the faculty personally just from working with them for a short period. 

Tell us about your co-interns. What has helped you connect, support each other, and form friendships?
My co-interns are all very impressive people, but still down-to-earth. I think the program leadership does a good job of selecting people who don’t take themselves too seriously.

What has surprised you most about Duke?
I'm still surprised at how nice everyone here is. 

About Duke University and Durham

What is the best thing about living in Durham and the Triangle?
Good restaurants, easy access to the wilderness, no traffic, great weather, what’s not to like?

How does the Triangle appeal to people of diverse backgrounds?
Don’t let the rest of NC give you the wrong impression, the Triangle is a diverse, progressive area, full of young open-minded people. There’s plenty of good restaurants, music venues, sports teams, museums, and wilderness around here to keep you busy in your free time. 

Where did you choose to live and why?
I'm renting a house near downtown with my wife. I wanted a fenced backyard for my dog, and I wanted to be close enough to bike to work and downtown.

What advice would you give to someone looking to move to Durham?
I would recommend driving around to get a feel for where you would want to live. There is pretty much no traffic around here so don't feel like you need to live near the hospital.

What are your interests outside of medicine?
I like to watch/play soccer, run, cook, and hang out with my wife and dog. 



Alexopoulos, Anastasia-Stefania, Ryan Duffy, Elizabeth A. Kobe, Jashalynn German, Cynthia A. Moylan, Diana Soliman, Amy S. Jeffreys, Cynthia J. Coffman, and Matthew J. Crowley. “Underrecognition of Nonalcoholic Fatty Liver Disease in Poorly Controlled Diabetes: A Call to Action in Diabetes Care.” J Endocr Soc 5, no. 12 (December 1, 2021): bvab155. https://doi.org/10.1210/jendso/bvab155.

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Duffy, Ryan A., Mathab B. Foroozesh, Robert D. Loflin, Susanti R. Ie, Bradley L. Icard, Allison N. Tegge, Jonathan R. Nogueira, Damon R. Kuehl, Dan C. Smith, and Anthony L. Loschner. “Normal saline versus Normosol™-R in sepsis resuscitation: A retrospective cohort study.” Journal of the Intensive Care Society 20, no. 3 (August 2019): 223–30. https://doi.org/10.1177/1751143718786113.

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Wen, Yingxia, Hung V. Trinh, Christine E. Linton, Chiara Tani, Nathalie Norais, DeeAnn Martinez-Guzman, Priyanka Ramesh, et al. “Generation and characterization of a bivalent protein boost for future clinical trials: HIV-1 subtypes CR01_AE and B gp120 antigens with a potent adjuvant.” Plos One 13, no. 4 (2018): e0194266. https://doi.org/10.1371/journal.pone.0194266.

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Wiehe, Kevin, Nathan I. Nicely, Bradley Lockwood, Masayuki Kuraoka, Kara Anasti, Sabrina Arora, Cindy M. Bowman, et al. “Immunodominance of Antibody Recognition of the HIV Envelope V2 Region in Ig-Humanized Mice.” J Immunol 198, no. 3 (February 1, 2017): 1047–55. https://doi.org/10.4049/jimmunol.1601640.

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Shen, Xiaoying, Ryan Duffy, Robert Howington, Alethea Cope, Shanmugalakshmi Sadagopal, Haesun Park, Ranajit Pal, et al. “Vaccine-Induced Linear Epitope-Specific Antibodies to Simian Immunodeficiency Virus SIVmac239 Envelope Are Distinct from Those Induced to the Human Immunodeficiency Virus Type 1 Envelope in Nonhuman Primates.” J Virol 89, no. 16 (August 2015): 8643–50. https://doi.org/10.1128/JVI.03635-14.

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Santra, Sampa, Georgia D. Tomaras, Ranjit Warrier, Nathan I. Nicely, Hua-Xin Liao, Justin Pollara, Pinghuang Liu, et al. “Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques.” Plos Pathog 11, no. 8 (August 2015): e1005042. https://doi.org/10.1371/journal.ppat.1005042.

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