Andrew Joseph Muir, MD

Professor of Medicine
Chief, Division of Gastroenterology in the Department of Medicine
Core Faculty in Innovation & Entrepreneurship
Member in the Duke Clinical Research Institute
Campus mail 03137B Hosp South, Durham, NC 27710
Phone (919) 684-2052
Email address andrew.muir@duke.edu
  • Hepatitis C 
  • Primary sclerosing cholangitis
  • Cirrhosis
  • Liver Transplantation
  • Clinical Trials
  • Healthcare disparities in liver disease 
  • Outcomes Research

Education and Training

  • Fellow in Gastroenterology, Medicine, Duke University, 1998 - 2000
  • Chief Medical Resident, Medicine, Duke University, 1997 - 1998
  • Fellow in Gastroenterology, Medicine, Duke University, 1996 - 1997
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.H.S., Duke University, 2001
  • M.D., Duke University, 1993

Grants

Publications

Dore, Gregory J., Jordan J. Feld, Alex Thompson, Marianne Martinello, Andrew J. Muir, Kosh Agarwal, Beat Müllhaupt, et al. “Simplified monitoring for hepatitis C virus treatment with glecaprevir plus pibrentasvir, a randomised non-inferiority trial.” J Hepatol 72, no. 3 (March 2020): 431–40. https://doi.org/10.1016/j.jhep.2019.10.010.

PMID
31655134
Full Text

Younossi, Zobair M., Maria Stepanova, Ira Jacobson, Andrew J. Muir, Stanislas Pol, Stefan Zeuzem, Ziad Younes, et al. “Not Achieving Sustained Viral Eradication of Hepatitis C Virus After Treatment Leads to Worsening Patient-reported Outcomes.” Clin Infect Dis 70, no. 4 (February 3, 2020): 628–32. https://doi.org/10.1093/cid/ciz243.

PMID
30949674
Full Text

Ocal, Selin, and Andrew J. Muir. “Addressing Hepatitis C in the American Incarcerated Population: Strategies for Nationwide Elimination.” Curr Hiv/Aids Rep 17, no. 1 (February 2020): 18–25. https://doi.org/10.1007/s11904-019-00476-z.

PMID
31933274
Full Text

Trauner, Michael, Yevgeniy Gindin, Zhaoshi Jiang, Chuhan Chung, G Mani Subramanian, Robert P. Myers, Aliya Gulamhusein, et al. “Methylation signatures in peripheral blood are associated with marked age acceleration and disease progression in patients with primary sclerosing cholangitis.” Jhep Rep 2, no. 1 (February 2020): 100060. https://doi.org/10.1016/j.jhepr.2019.11.004.

PMID
32039401
Full Text

Sanyal, Arun J., Stephen A. Harrison, Vlad Ratziu, Manal F. Abdelmalek, Anna Mae Diehl, Stephen Caldwell, Mitchell L. Shiffman, et al. “The Natural History of Advanced Fibrosis Due to Nonalcoholic Steatohepatitis: Data From the Simtuzumab Trials.” Hepatology 70, no. 6 (December 2019): 1913–27. https://doi.org/10.1002/hep.30664.

PMID
30993748
Full Text

Muir, Andrew J. “Is Magnetic Resonance Cholangiopancreatography Worth a Thousand Words in Determining Prognoses of Patients With Primary Sclerosing Cholangitis?” Clin Gastroenterol Hepatol 17, no. 13 (December 2019): 2654–56. https://doi.org/10.1016/j.cgh.2019.04.067.

PMID
31077831
Full Text

Brahmania, Mayur, Manuel Lombardero, Bettina E. Hansen, Norah A. Terrault, Anna S. Lok, Robert P. Perrillo, Steven H. Belle, et al. “Association Between Severe Serum Alanine Aminotransferase Flares and Hepatitis B e Antigen Seroconversion and HBV DNA Decrease in Untreated Patients With Chronic HBV Infection.” Clin Gastroenterol Hepatol 17, no. 12 (November 2019): 2541-2551.e2. https://doi.org/10.1016/j.cgh.2019.02.005.

PMID
30743006
Full Text

Ocal, Selin, Andrew J. Muir, and Susanna Naggie. “Hepatitis C Behind and Beyond Bars: Targeting the US Prison Population and Changing North Carolina Prisoner Health Policy.” N C Med J 80, no. 6 (November 2019): 352–55. https://doi.org/10.18043/ncm.80.6.352.

PMID
31685570
Full Text

Thorburn, Douglas, Mette Juul Nielsen, Jun Xu, Ya Wang, Guang Chen, Andrew Billin, Ryan Huss, et al. “ASSOCIATIONS BETWEEN SEROLOGIC MARKERS OF EXTRACELLULAR MATRIX (ECM) REMODELING WITH FIBROSIS STAGE AND PROGNOSIS IN PATIENTS WITH PRIMARY SCLEROSING CHOLANGITIS (PSC).” In Hepatology, 70:800A-800A. WILEY, 2019.

Scholars@Duke

Trauner, Michael H., Yevgeniy Gindin, Jing Zhu Zhou, Ryan Huss, Chuhan Chung, Mani Subramanian, Robert P. Myers, et al. “RNA-SEQ FROM PATIENTS WITH PRIMARY SCLEROSING CHOLANGITIS IDENTIFIES A FIBROSIS-INDEPENDENT GENE EXPRESSION SIGNATURE THAT PREDICTS CLINICAL EVENTS.” In Hepatology, 70:758A-759A. WILEY, 2019.

Scholars@Duke

Pages