Anthony D Sung, MD

Assistant Professor of Medicine
Member of the Duke Cancer Institute
Campus mail Box 3961 Med Ctr, Durham, NC 27710
Phone (919) 668-1000
Email address anthony.sung@duke.edu

I am dedicated to the treatment of hematologic malignancies through cellular therapies such as hematopoietic stem cell transplantation (HCT). My research focuses on strategies to reduce complications of HCT and ranges from preclinical studies using murine models of HCT to Phase 1 and Phase 2 clinical trials. Areas of interest include the role of the microbiota (the trillions of bacteria living in and on our bodies), nutrition, and exercise in modulating HCT outcomes such as graft-versus-host disease (GVHD) and infections. In addition to advancing new pharmacological and cellular immunotherapies in support of these goals, we also are developing mobile health technologies (mHealth) to monitor patients at home, both as part of our innovative home transplant program as well as to improve follow up care of all our patients when they return home after transplant.

In Their Words

Education and Training

  • Fellowship, Hematology Oncology, Duke University School of Medicine, 2011 - 2014
  • Residency, Osler Medical Housestaff Training Program, Johns Hopkins University School of Medicine, 2008 - 2011
  • M.D., Harvard University , 2008

Publications

O’Sullivan, Madeline L., Rebecca A. Shelby, Caroline S. Dorfman, Sarah A. Kelleher, Hannah M. Fisher, Krista A. Rowe Nichols, Francis J. Keefe, Anthony D. Sung, and Tamara J. Somers. “The effect of pre-transplant pain and chronic disease self-efficacy on quality of life domains in the year following hematopoietic stem cell transplantation..” Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer 26, no. 4 (April 2018): 1243–52. https://doi.org/10.1007/s00520-017-3947-6.

PMID
29124418
Full Text

Sung, Anthony D., Syed Hassan, Diana M. Cardona, Daniel Wild, Krista Rowe Nichols, Hossein Mehdikhani, Bryan Balmadrid, et al. “Late Gastrointestinal Complications of Allogeneic Hematopoietic Stem Cell Transplantation in Adults..” Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation 24, no. 4 (April 2018): 734–40. https://doi.org/10.1016/j.bbmt.2017.12.772.

PMID
29246821
Full Text

DeFilipp, Zachariah, Jonathan U. Peled, Shuli Li, Jasmin Mahabamunuge, Zeina Dagher, Ann E. Slingerland, Candice Del Rio, et al. “Third-party fecal microbiota transplantation following allo-HCT reconstitutes microbiome diversity..” Blood Advances 2, no. 7 (April 2018): 745–53. https://doi.org/10.1182/bloodadvances.2018017731.

PMID
29592876
Full Text

Peled, Jonathan U., Antonio Gomes, Marissa Lubin Buchan, Christoph Stein-Thoeringer, John Slingerland, Ann E. Slingerland, Daniela Weber, et al. “Intestinal Microbiota Injury during Allo-Hct is Generalizable across Transplantation Centers and is Associated with Increased Mortality, Broad-Spectrum Antibiotics, and Decreased Calorie Intake.” In Biology of Blood and Marrow Transplantation, 24:S21–22. ELSEVIER SCIENCE INC, 2018.

Scholars@Duke

Guo, Mei, Nelson J. Chao, Jian-Yong Li, David A. Rizzieri, Qi-Yun Sun, Ann Mohrbacher, Elizabeth F. Krakow, et al. “HLA-Mismatched Microtransplant in Older Patients Newly Diagnosed With Acute Myeloid Leukemia: Results From the Microtransplantation Interest Group..” Jama Oncology 4, no. 1 (January 2018): 54–62. https://doi.org/10.1001/jamaoncol.2017.2656.

PMID
28910431
Full Text

Wong, Hong Yuen, Anthony D. Sung, Katherine E. Lindblad, Sheenu Sheela, Gregory W. Roloff, David Rizzieri, Meghali Goswami, et al. “Molecular Measurable Residual Disease Testing of Blood During AML Cytotoxic Therapy for Early Prediction of Clinical Response..” Frontiers in Oncology 8 (January 2018). https://doi.org/10.3389/fonc.2018.00669.

PMID
30697529
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Anand, Sarah, Samantha Thomas, Kelly Corbet, Cristina Gasparetto, Gwynn D. Long, Richard Lopez, Ashley K. Morris, et al. “Adult Umbilical Cord Blood Transplantation Using Myeloablative Thiotepa, Total Body Irradiation, and Fludarabine Conditioning..” In Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation, 23:1949–54, 2017. https://doi.org/10.1016/j.bbmt.2017.06.027.

PMID
28729147
Full Text

Anand, Sarah, Samantha Thomas, Terry Hyslop, Janet Adcock, Kelly Corbet, Cristina Gasparetto, Richard Lopez, et al. “Transplantation of Ex Vivo Expanded Umbilical Cord Blood (NiCord) Decreases Early Infection and Hospitalization..” Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation 23, no. 7 (July 2017): 1151–57. https://doi.org/10.1016/j.bbmt.2017.04.001.

PMID
28392378
Full Text

Peled, Jonathan U., Sean M. Devlin, Anna Staffas, Melissa Lumish, Raya Khanin, Eric R. Littmann, Lilan Ling, et al. “Intestinal Microbiota and Relapse After Hematopoietic-Cell Transplantation..” Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology 35, no. 15 (May 2017): 1650–59. https://doi.org/10.1200/JCO.2016.70.3348.

PMID
28296584
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Sivaraj, Dharshan, Michael M. Green, Zhiguo Li, Anthony D. Sung, Stefanie Sarantopoulos, Yubin Kang, Gwynn D. Long, et al. “Outcomes of Maintenance Therapy with Bortezomib after Autologous Stem Cell Transplantation for Patients with Multiple Myeloma..” Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation 23, no. 2 (February 2017): 262–68. https://doi.org/10.1016/j.bbmt.2016.11.010.

PMID
27856369
Full Text

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