Anthony D Sung, MD

Associate Professor of Medicine
Member of the Duke Cancer Institute
Senior Fellow in the Duke Center for the Study of Aging and Human Development
Campus mail Box 3961 Med Ctr, Durham, NC 27710
Phone (919) 668-1000
Email address anthony.sung@duke.edu

I am dedicated to the treatment of hematologic malignancies through cellular therapies such as hematopoietic stem cell transplantation (HCT). My research focuses on strategies to reduce complications of HCT and ranges from preclinical studies using murine models of HCT to Phase 1 and Phase 2 clinical trials. Areas of interest include the role of the microbiota (the trillions of bacteria living in and on our bodies), nutrition, and exercise in modulating HCT outcomes such as graft-versus-host disease (GVHD) and infections. In addition to advancing new pharmacological and cellular immunotherapies in support of these goals, we also are developing mobile health technologies (mHealth) to monitor patients at home, both as part of our innovative home transplant program as well as to improve follow up care of all our patients when they return home after transplant.

In Their Words

Education and Training

  • Fellowship, Hematology Oncology, Duke University School of Medicine, 2011 - 2014
  • Residency, Osler Medical Housestaff Training Program, Johns Hopkins University School of Medicine, 2008 - 2011
  • M.D., Harvard University , 2008

Grants

Publications

Maung, Ko, Sendhilnathan Ramalingam, Mohammad Chaudhry, Yi Ren, Sin-Ho Jung, Kristi Romero, Kelly Corbet, et al. “Pre-transplant hepatic steatosis (fatty liver) is associated with chronic graft-vs-host disease but not mortality.” Plos One 15, no. 9 (2020): e0238824. https://doi.org/10.1371/journal.pone.0238824.

PMID
32915853
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Stein-Thoeringer, C. K., K. B. Nichols, A. Lazrak, M. D. Docampo, A. E. Slingerland, J. B. Slingerland, A. G. Clurman, et al. “Lactose drives Enterococcus expansion to promote graft-versus-host disease.” Science 366, no. 6469 (November 29, 2019): 1143–49. https://doi.org/10.1126/science.aax3760.

PMID
31780560
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Cardones, Adela R., Keith M. Sullivan, Cindy Green, Nelson J. Chao, Krista Rowe-Nichols, Lionel L. Bañez, Claude S. Burton, et al. “Interrater Reliability of Clinical Grading Measures for Cutaneous Chronic Graft-vs-Host Disease.” Jama Dermatol 155, no. 7 (July 1, 2019): 833–37. https://doi.org/10.1001/jamadermatol.2018.5459.

PMID
30994873
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Peled, Jonathan U., Antonio L. C. Gomes, Sean M. Devlin, Eric R. Littmann, Ying Taur, Anthony Derek Sung, Daniela Weber, et al. “Inferior survival after microbiota injury: A multicenter alto-HCT study.” In Journal of Clinical Oncology, Vol. 37. AMER SOC CLINICAL ONCOLOGY, 2019.

Scholars@Duke

Spees, Lisa P., Paul L. Martin, Joanne Kurtzberg, Andre Stokhuyzen, Lauren McGill, Vinod K. Prasad, Timothy A. Driscoll, et al. “Reduction in Mortality after Umbilical Cord Blood Transplantation in Children Over a 20-Year Period (1995-2014).” Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation 25, no. 4 (April 2019): 756–63. https://doi.org/10.1016/j.bbmt.2018.11.018.

PMID
30481599
Full Text

Peled, Jonathan U., Antonio Gomes, Christoph Stein-Thoeringer, John Slingerland, Ann E. Slingerland, Daniela Weber, Kate Ann Markey, et al. “Multicenter Microbiota Analysis Indicates That Pre-HCT Microbiota Injury Is Prevalent across Geography and Predicts Poor Overall Survival.” In Biology of Blood and Marrow Transplantation, Vol. 25, 2019.

Scholars@Duke

Kegerreis, Kristin G., Yvonne M. Mowery, Martha Lassiter, Erica Lobaugh-Jin, and Anthony D. Sung. “Demonstrating Efficacy of CHG Bathing Treatment for Inpatient Adult Hematopoietic Stem Cell Transplant Recipients Improves Daily Compliance Among Staff.” In Biology of Blood and Marrow Transplantation, Vol. 25, 2019.

Scholars@Duke

Khan, Niloufer, Jonathan U. Peled, Antonio Gomes, Sean M. Devlin, Carlos Rondon Clavo, Annelie Clurman, John Slingerland, et al. “Microbiota Injury in Auto-HCT Is Frequent, Occurs across Geography, and Is Comparable to That Observed in Allo-HCT.” In Biology of Blood and Marrow Transplantation, Vol. 25, 2019.

Scholars@Duke

Lowder, Yen P., Meredith Moyers, Jenna Seckar, Elisabeth Gorecki, Kelli Oldham, Jennifer Frutchey, Kara Beasley, et al. “Nutrition Practices in Hematopoietic Stem Cell Transplantation (HSCT): A Comparison between Guidelines and Clinical Practice.” In Biology of Blood and Marrow Transplantation, Vol. 25, 2019.

Scholars@Duke

Peled, Jonathan U., Antonio L. C. Gomes, Christoph K. Stein-Thoeringer, John B. Slingerland, Ann E. Slingerland, Daniela Weber, Kate A. Markey, et al. “Multicenter Microbiota Analysis Indicates That Pre-HCT Microbiota Injury Is Prevalent across Geography and Predicts Poor Overall Survival.” In Blood, 132:811–811. American Society of Hematology, 2018. https://doi.org/10.1182/blood-2018-99-116967.

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