Barbara Dudley Alexander, MD

Professor of Medicine
Professor of Pathology
Campus mail 315 Trent Drive, Hanes House, Room 163A, Durham, NC 27710
Phone (919) 668-0789
Email address alexa011@mc.duke.edu

Clinical research related to infectious complications of solid organ and bone marrow transplantation, with a particular interest in the treatment and rapid diagnosis of fungal disease.

Education and Training

  • Fellow, Infectious Diseases, Medicine, Duke University, 1996 - 1998
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.D., East Carolina University, 1993

Publications

Plantinga, TS, Johnson, MD, Scott, WK, van de Vosse, E, Velez Edwards, DR, Smith, PB, Alexander, BD, Yang, JC, Kremer, D, Laird, GM, Oosting, M, Joosten, LAB, van der Meer, JWM, van Dissel, JT, Walsh, TJ, Perfect, JR, Kullberg, BJ, and Netea, MG. "Toll-like receptor 1 polymorphisms increase susceptibility to candidemia." J Infect Dis 205, no. 6 (March 15, 2012): 934-943.

PMID
22301633
Full Text

Rosentul, DC, Plantinga, TS, Scott, WK, Alexander, BD, van de Geer, NMD, Perfect, JR, Kullberg, BJ, Johnson, MD, and Netea, MG. "The impact of caspase-12 on susceptibility to candidemia." Eur J Clin Microbiol Infect Dis 31, no. 3 (March 2012): 277-280.

PMID
21706251
Full Text

Johnson, MD, Plantinga, TS, van de Vosse, E, Velez Edwards, DR, Smith, PB, Alexander, BD, Yang, JC, Kremer, D, Laird, GM, Oosting, M, Joosten, LAB, van der Meer, JWM, van Dissel, JT, Walsh, TJ, Perfect, JR, Kullberg, B-J, Scott, WK, and Netea, MG. "Cytokine gene polymorphisms and the outcome of invasive candidiasis: a prospective cohort study." Clin Infect Dis 54, no. 4 (February 15, 2012): 502-510.

PMID
22144535
Full Text

Hanson, KE, Pfeiffer, CD, Lease, ED, Balch, AH, Zaas, AK, Perfect, JR, and Alexander, BD. "β-D-glucan surveillance with preemptive anidulafungin for invasive candidiasis in intensive care unit patients: a randomized pilot study." PLoS One 7, no. 8 (2012): e42282-.

PMID
22879929
Full Text

Lease, ED, and Alexander, BD. "Fungal diagnostics in pneumonia." Semin Respir Crit Care Med 32, no. 6 (December 2011): 663-672. (Review)

PMID
22167394
Full Text

Alexander, BD, Winkler, TP, Shi, S, Dodds Ashley, ES, and Hickey, AJ. "In vitro characterization of nebulizer delivery of liposomal amphotericin B aerosols." Pharmaceutical development and technology 16, no. 6 (November 2011): 577-582. (Academic Article)

PMID
21699390
Full Text

Rosentul, DC, Plantinga, TS, Oosting, M, Scott, WK, Velez Edwards, DR, Smith, PB, Alexander, BD, Yang, JC, Laird, GM, Joosten, LAB, van der Meer, JWM, Perfect, JR, Kullberg, B-J, Netea, MG, and Johnson, MD. "Genetic variation in the dectin-1/CARD9 recognition pathway and susceptibility to candidemia." J Infect Dis 204, no. 7 (October 1, 2011): 1138-1145.

PMID
21881131
Full Text

Park, BJ, Pappas, PG, Wannemuehler, KA, Alexander, BD, Anaissie, EJ, Andes, DR, Baddley, JW, Brown, JM, Brumble, LM, Freifeld, AG, Hadley, S, Herwaldt, L, Ito, JI, Kauffman, CA, Lyon, GM, Marr, KA, Morrison, VA, Papanicolaou, G, Patterson, TF, Perl, TM, Schuster, MG, Walker, R, Wingard, JR, Walsh, TJ, and Kontoyiannis, DP. "Invasive non-Aspergillus mold infections in transplant recipients, United States, 2001-2006." Emerg Infect Dis 17, no. 10 (October 2011): 1855-1864.

PMID
22000355
Full Text

Pfeiffer, CD, Samsa, GP, Schell, WA, Reller, LB, Perfect, JR, and Alexander, BD. "Quantitation of Candida CFU in initial positive blood cultures." J Clin Microbiol 49, no. 8 (August 2011): 2879-2883.

PMID
21677065
Full Text

Pfaller, MA, Andes, D, Arendrup, MC, Diekema, DJ, Espinel-Ingroff, A, Alexander, BD, Brown, SD, Chaturvedi, V, Fowler, CL, Ghannoum, MA, Johnson, EM, Knapp, CC, Motyl, MR, Ostrosky-Zeichner, L, and Walsh, TJ. "Clinical breakpoints for voriconazole and Candida spp. revisited: review of microbiologic, molecular, pharmacodynamic, and clinical data as they pertain to the development of species-specific interpretive criteria." Diagn Microbiol Infect Dis 70, no. 3 (July 2011): 330-343. (Review)

PMID
21546199
Full Text

Pages