Barbara Dudley Alexander, MD

Professor of Medicine
Professor of Pathology
Campus mail 315 Trent Drive, Hanes House, Room 163A, Durham, NC 27710
Phone (919) 668-0789
Email address alexa011@mc.duke.edu

Clinical research related to infectious complications of solid organ and bone marrow transplantation, with a particular interest in the treatment and rapid diagnosis of fungal disease.

Education and Training

  • Fellow, Infectious Diseases, Medicine, Duke University, 1996 - 1998
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.D., East Carolina University, 1993

Publications

Lamoth, Frédéric, Lauro Damonti, and Barbara D. Alexander. “Role of Antifungal Susceptibility Testing in Non-Aspergillus Invasive Mold Infections.” J Clin Microbiol 54, no. 6 (June 2016): 1638–40. https://doi.org/10.1128/JCM.00318-16.

PMID
27008871
Full Text

Healey, Kelley R., Yanan Zhao, Winder B. Perez, Shawn R. Lockhart, Jack D. Sobel, Dimitrios Farmakiotis, Dimitrios P. Kontoyiannis, et al. “Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance.” Nat Commun 7 (March 29, 2016): 11128. https://doi.org/10.1038/ncomms11128.

PMID
27020939
Full Text

Husain, Shahid, Amparo Sole, Barbara D. Alexander, Saima Aslam, Robin Avery, Christian Benden, Eliane M. Billaud, et al. “The 2015 International Society for Heart and Lung Transplantation Guidelines for the management of fungal infections in mechanical circulatory support and cardiothoracic organ transplant recipients: Executive summary.” J Heart Lung Transplant 35, no. 3 (March 2016): 261–82. https://doi.org/10.1016/j.healun.2016.01.007.

PMID
26970469
Full Text

Swamydas, Muthulekha, Ji-Liang Gao, Timothy J. Break, Melissa D. Johnson, Martin Jaeger, Carlos A. Rodriguez, Jean K. Lim, et al. “CXCR1-mediated neutrophil degranulation and fungal killing promote Candida clearance and host survival.” Sci Transl Med 8, no. 322 (January 20, 2016): 322ra10. https://doi.org/10.1126/scitranslmed.aac7718.

PMID
26791948
Full Text

Lamoth, F., and B. D. Alexander. “Antifungal Susceptibility Testing to Predict Appropriate Initial Antifungal Therapy and Outcome in non-Aspergillus Invasive Mold Infections.” In Mycoses, 58:171–171. WILEY-BLACKWELL, 2015.

Scholars@Duke

Lamoth, Frédéric, and Barbara D. Alexander. “Comparing Etest and Broth Microdilution for Antifungal Susceptibility Testing of the Most-Relevant Pathogenic Molds.” J Clin Microbiol 53, no. 10 (October 2015): 3176–81. https://doi.org/10.1128/JCM.00925-15.

PMID
26202113
Full Text

Lamoth, Frédéric, and Barbara D. Alexander. “Antifungal activities of SCY-078 (MK-3118) and standard antifungal agents against clinical non-Aspergillus mold isolates.” Antimicrob Agents Chemother 59, no. 7 (July 2015): 4308–11. https://doi.org/10.1128/AAC.00234-15.

PMID
25896696
Full Text

McCarty, Todd P., John W. Baddley, Thomas J. Walsh, Barbara D. Alexander, Dimitrios P. Kontoyiannis, Trish M. Perl, Randall Walker, et al. “Phaeohyphomycosis in transplant recipients: Results from the Transplant Associated Infection Surveillance Network (TRANSNET).” Med Mycol 53, no. 5 (June 2015): 440–46. https://doi.org/10.1093/mmy/myv018.

PMID
25908651
Full Text

Lamoth, Frédéric, Barbara D. Alexander, Praveen R. Juvvadi, and William J. Steinbach. “Antifungal activity of compounds targeting the Hsp90-calcineurin pathway against various mould species.” J Antimicrob Chemother 70, no. 5 (May 2015): 1408–11. https://doi.org/10.1093/jac/dku549.

PMID
25558076
Full Text

Patel, Ravi M., Sarah Kandefer, Michele C. Walsh, Edward F. Bell, Waldemar A. Carlo, Abbot R. Laptook, Pablo J. Sánchez, et al. “Causes and timing of death in extremely premature infants from 2000 through 2011.” N Engl J Med 372, no. 4 (January 22, 2015): 331–40. https://doi.org/10.1056/NEJMoa1403489.

PMID
25607427
Full Text

Pages