Christopher Vine Plowe, MD

Professor of Medicine
Director, Duke Global Health Institute
Research Professor of Global Health
Professor in the Department of Molecular Genetics and Microbiology
Email address chris.plowe@duke.edu

Education and Training

  • Clinical Infectious Diseases Fellowship, Medicine, Johns Hopkins University School of Medicine, 1994 - 1995
  • Clinical & Research Associate, NIAID, Laboratory Of Malaria Research, National Institutes of Health, 1991 - 1994
  • Internal Medicine Chief Resident, Columbia University College of Physicians and Surgeons, 1990 - 1991
  • International Fellows Program, Columbia University College of Physicians and Surgeons, 1989 - 1990
  • Internal Medicine Internship and Residency, Columbia University, 1986 - 1989
  • M.P.H., Columbia University, 1991
  • M.D., Weill Cornell Medical College, 1986

Publications

Chaorattanakawee, Suwanna, David L. Saunders, Darapiseth Sea, Nitima Chanarat, Kritsanai Yingyuen, Siratchana Sundrakes, Piyaporn Saingam, et al. “Ex Vivo Drug Susceptibility Testing and Molecular Profiling of Clinical Plasmodium falciparum Isolates from Cambodia from 2008 to 2013 Suggest Emerging Piperaquine Resistance..” Antimicrob Agents Chemother 59, no. 8 (August 2015): 4631–43. https://doi.org/10.1128/AAC.00366-15.

PMID
26014942
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Travassos, Mark A., Drissa Coulibaly, Jason A. Bailey, Amadou Niangaly, Matthew Adams, Myaing M. Nyunt, Amed Ouattara, et al. “Differential recognition of terminal extracellular Plasmodium falciparum VAR2CSA domains by sera from multigravid, malaria-exposed Malian women..” Am J Trop Med Hyg 92, no. 6 (June 2015): 1190–94. https://doi.org/10.4269/ajtmh.14-0524.

PMID
25918203
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Ouattara, Amed, Aminatou Kone, Matthew Adams, Bakary Fofana, Amelia Walling Maiga, Shay Hampton, Drissa Coulibaly, et al. “Polymorphisms in the K13-propeller gene in artemisinin-susceptible Plasmodium falciparum parasites from Bougoula-Hameau and Bandiagara, Mali..” Am J Trop Med Hyg 92, no. 6 (June 2015): 1202–6. https://doi.org/10.4269/ajtmh.14-0605.

PMID
25918205
Full Text

White, Lisa J., Jennifer A. Flegg, Aung Pyae Phyo, Ja Hser Wiladpai-ngern, Delia Bethell, Christopher Plowe, Tim Anderson, et al. “Defining the in vivo phenotype of artemisinin-resistant falciparum malaria: a modelling approach..” Plos Med 12, no. 4 (April 2015). https://doi.org/10.1371/journal.pmed.1001823.

PMID
25919029
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Takala-Harrison, Shannon, Christopher G. Jacob, Cesar Arze, Michael P. Cummings, Joana C. Silva, Arjen M. Dondorp, Mark M. Fukuda, et al. “Independent emergence of artemisinin resistance mutations among Plasmodium falciparum in Southeast Asia..” J Infect Dis 211, no. 5 (March 1, 2015): 670–79. https://doi.org/10.1093/infdis/jiu491.

PMID
25180241
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Brown, Tyler S., Christopher G. Jacob, Joana C. Silva, Shannon Takala-Harrison, Abdoulaye Djimdé, Arjen M. Dondorp, Mark Fukuda, et al. “Plasmodium falciparum field isolates from areas of repeated emergence of drug resistant malaria show no evidence of hypermutator phenotype..” Infect Genet Evol 30 (March 2015): 318–22. https://doi.org/10.1016/j.meegid.2014.12.010.

PMID
25514047
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Miotto, Olivo, Roberto Amato, Elizabeth A. Ashley, Bronwyn MacInnis, Jacob Almagro-Garcia, Chanaki Amaratunga, Pharath Lim, et al. “Genetic architecture of artemisinin-resistant Plasmodium falciparum..” Nat Genet 47, no. 3 (March 2015): 226–34. https://doi.org/10.1038/ng.3189.

PMID
25599401
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Bailey, Jason A., Jozelyn Pablo, Amadou Niangaly, Mark A. Travassos, Amed Ouattara, Drissa Coulibaly, Matthew B. Laurens, et al. “Seroreactivity to a large panel of field-derived Plasmodium falciparum apical membrane antigen 1 and merozoite surface protein 1 variants reflects seasonal and lifetime acquired responses to malaria..” Am J Trop Med Hyg 92, no. 1 (January 2015): 9–12. https://doi.org/10.4269/ajtmh.14-0140.

PMID
25294612
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Frosch, Anne E. P., Miriam K. Laufer, Don P. Mathanga, Shannon Takala-Harrison, Jacek Skarbinski, Cassidy W. Claassen, Fraction K. Dzinjalamala, and Christopher V. Plowe. “Return of widespread chloroquine-sensitive Plasmodium falciparum to Malawi..” J Infect Dis 210, no. 7 (October 1, 2014): 1110–14. https://doi.org/10.1093/infdis/jiu216.

PMID
24723474
Full Text

Pages