Christopher Vine Plowe, MD

Professor of Medicine
Director, Duke Global Health Institute
Research Professor of Global Health
Professor in the Department of Molecular Genetics and Microbiology
Email address chris.plowe@duke.edu

Education and Training

  • Clinical Infectious Diseases Fellowship, Medicine, Johns Hopkins University School of Medicine, 1994 - 1995
  • Clinical & Research Associate, NIAID, Laboratory Of Malaria Research, National Institutes of Health, 1991 - 1994
  • Internal Medicine Chief Resident, Columbia University College of Physicians and Surgeons, 1990 - 1991
  • International Fellows Program, Columbia University College of Physicians and Surgeons, 1989 - 1990
  • Internal Medicine Internship and Residency, Columbia University, 1986 - 1989
  • M.P.H., Columbia University, 1991
  • M.D., Weill Cornell Medical College, 1986

Publications

Takala-Harrison, Shannon, Christopher G. Jacob, Cesar Arze, Michael P. Cummings, Joana C. Silva, Arjen M. Dondorp, Mark M. Fukuda, et al. “Independent emergence of artemisinin resistance mutations among Plasmodium falciparum in Southeast Asia..” J Infect Dis 211, no. 5 (March 1, 2015): 670–79. https://doi.org/10.1093/infdis/jiu491.

PMID
25180241
Full Text

Brown, Tyler S., Christopher G. Jacob, Joana C. Silva, Shannon Takala-Harrison, Abdoulaye Djimdé, Arjen M. Dondorp, Mark Fukuda, et al. “Plasmodium falciparum field isolates from areas of repeated emergence of drug resistant malaria show no evidence of hypermutator phenotype..” Infect Genet Evol 30 (March 2015): 318–22. https://doi.org/10.1016/j.meegid.2014.12.010.

PMID
25514047
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Miotto, Olivo, Roberto Amato, Elizabeth A. Ashley, Bronwyn MacInnis, Jacob Almagro-Garcia, Chanaki Amaratunga, Pharath Lim, et al. “Genetic architecture of artemisinin-resistant Plasmodium falciparum..” Nat Genet 47, no. 3 (March 2015): 226–34. https://doi.org/10.1038/ng.3189.

PMID
25599401
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Bailey, Jason A., Jozelyn Pablo, Amadou Niangaly, Mark A. Travassos, Amed Ouattara, Drissa Coulibaly, Matthew B. Laurens, et al. “Seroreactivity to a large panel of field-derived Plasmodium falciparum apical membrane antigen 1 and merozoite surface protein 1 variants reflects seasonal and lifetime acquired responses to malaria..” Am J Trop Med Hyg 92, no. 1 (January 2015): 9–12. https://doi.org/10.4269/ajtmh.14-0140.

PMID
25294612
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Frosch, Anne E. P., Miriam K. Laufer, Don P. Mathanga, Shannon Takala-Harrison, Jacek Skarbinski, Cassidy W. Claassen, Fraction K. Dzinjalamala, and Christopher V. Plowe. “Return of widespread chloroquine-sensitive Plasmodium falciparum to Malawi..” J Infect Dis 210, no. 7 (October 1, 2014): 1110–14. https://doi.org/10.1093/infdis/jiu216.

PMID
24723474
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Venkatesan, Meera, Nahla B. Gadalla, Kasia Stepniewska, Prabin Dahal, Christian Nsanzabana, Clarissa Moriera, Ric N. Price, et al. “Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine..” Am J Trop Med Hyg 91, no. 4 (October 2014): 833–43. https://doi.org/10.4269/ajtmh.14-0031.

PMID
25048375
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Coulibaly, Drissa, Mark A. Travassos, Abdoulaye K. Kone, Youssouf Tolo, Matthew B. Laurens, Karim Traore, Issa Diarra, et al. “Stable malaria incidence despite scaling up control strategies in a malaria vaccine-testing site in Mali..” Malar J 13 (September 19, 2014). https://doi.org/10.1186/1475-2875-13-374.

PMID
25238721
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Shekalaghe, Seif, Mastidia Rutaihwa, Peter F. Billingsley, Mwajuma Chemba, Claudia A. Daubenberger, Eric R. James, Maximillian Mpina, et al. “Controlled human malaria infection of Tanzanians by intradermal injection of aseptic, purified, cryopreserved Plasmodium falciparum sporozoites..” Am J Trop Med Hyg 91, no. 3 (September 2014): 471–80. https://doi.org/10.4269/ajtmh.14-0119.

PMID
25070995
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Jacob, Christopher G., John C. Tan, Becky A. Miller, Asako Tan, Shannon Takala-Harrison, Michael T. Ferdig, and Christopher V. Plowe. “A microarray platform and novel SNP calling algorithm to evaluate Plasmodium falciparum field samples of low DNA quantity..” Bmc Genomics 15 (August 26, 2014). https://doi.org/10.1186/1471-2164-15-719.

PMID
25159520
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Gilliams, Elizabeth A., Jibreel Jumare, Cassidy W. Claassen, Phillip C. Thesing, Osward M. Nyirenda, Fraction K. Dzinjalamala, Terrie Taylor, Christopher V. Plowe, LaRee A. Tracy, and Miriam K. Laufer. “Chloroquine-azithromycin combination antimalarial treatment decreases risk of respiratory- and gastrointestinal-tract infections in Malawian children..” J Infect Dis 210, no. 4 (August 15, 2014): 585–92. https://doi.org/10.1093/infdis/jiu171.

PMID
24652498
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Pages