Connie Watkins Bales, PhD

Professor in Medicine
Senior Fellow in the Center for the Study of Aging and Human Development
Campus mail 2508 Busse Bldg, Durham, NC 27710
Phone (919) 660-7519
Email address bales001@mc.duke.edu

Research in our laboratory focuses on the role of nutrition (particularly vitamins and minerals) in the prevention and management of chronic diseases in older adults. Previous studies have concerned trace elements and cardiovascular disease, calcium and osteoporosis, and renal synthesis of vitamin D as it relates to bone health. Some of our newest work emphasizes the role of micronutrients as antioxidants and their interaction with the aging process. We are also working on various aspects of energy balance in older adults, ranging from failure to thrive in stroke patients with dysphagia to exercise and nutrition effects in overweight subjects who begin physical training. Thus we have a number of clinical and epidemiological projects on-going, many of which include a strong emphasis on nutrition assessment techniques in middle-aged and elderly subjects.

Education and Training

  • Ph.D., University of Tennessee at Knoxville, 1981

Publications

Freeland-Graves, J. H., F. Behmardi, C. W. Bales, V. Dougherty, P. H. Lin, J. B. Crosby, and P. C. Trickett. “Metabolic balance of manganese in young men consuming diets containing five levels of dietary manganese..” The Journal of Nutrition 118, no. 6 (June 1988): 764–73. https://doi.org/10.1093/jn/118.6.764.

PMID
3373341
Full Text

Bales, C. W., T. A. Davis, and R. E. Beauchene. “Long-term protein and calorie restriction: alterations in nucleic acid levels of organs of male rats..” Experimental Gerontology 23, no. 3 (January 1988): 189–96. https://doi.org/10.1016/0531-5565(88)90006-x.

PMID
2462506
Full Text

Friedman, B. J., J. H. Freeland-Graves, C. W. Bales, F. Behmardi, R. L. Shorey-Kutschke, R. A. Willis, J. B. Crosby, P. C. Trickett, and S. D. Houston. “Manganese balance and clinical observations in young men fed a manganese-deficient diet..” The Journal of Nutrition 117, no. 1 (January 1987): 133–43. https://doi.org/10.1093/jn/117.1.133.

PMID
3819860
Full Text

Bales, C. W., L. C. Steinman, J. H. Freeland-Graves, J. M. Stone, and R. K. Young. “The effect of age on plasma zinc uptake and taste acuity..” The American Journal of Clinical Nutrition 44, no. 5 (November 1986): 664–69. https://doi.org/10.1093/ajcn/44.5.664.

PMID
3766451
Full Text

Bales, C. W., M. C. Wang, J. H. Freeland-Graves, and R. S. Pobocik. “The effect of zinc deficiency and food restriction on prostaglandin E2 and thromboxane B2 in saliva and plasma of rats..” Prostaglandins 31, no. 5 (May 1986): 859–68. https://doi.org/10.1016/0090-6980(86)90019-5.

PMID
3460117
Full Text

Beauchene, R. E., C. W. Bales, C. S. Bragg, S. T. Hawkins, and R. L. Mason. “Effect of age of initiation of feed restriction on growth, body composition, and longevity of rats..” Journal of Gerontology 41, no. 1 (January 1986): 13–19. https://doi.org/10.1093/geronj/41.1.13.

PMID
3941250
Full Text

Bales, C. W., M. L. Chen, and J. H. Freeland-Graves. “The effects of a manganese deficiency on plasma amino acid concentrations in young adult males.” Federation Proceedings 44, no. 6 (January 1, 1985).

Scholars@Duke

Hurd, S., R. L. Shorey, J. Freeland-Graves, and C. Bales. “Formula diets omitting manganese promote a decline in total plasma cholesterol.” Federation Proceedings 43, no. 4 (January 1, 1984).

Scholars@Duke

Bales, C. W., J. H. Freeland-Graves, and J. J. Fickel. “Saliva concentrations of zinc, magnesium and copper in a human population.” Federation Proceedings 43, no. 3 (January 1, 1984).

Scholars@Duke

Davis, T. A., C. W. Bales, and R. E. Beauchene. “Differential effects of dietary caloric and protein restriction in the aging rat..” Experimental Gerontology 18, no. 6 (January 1983): 427–35. https://doi.org/10.1016/0531-5565(83)90021-9.

PMID
6673988
Full Text

Pages