Connie Watkins Bales, PhD

Professor in Medicine
Senior Fellow in the Center for the Study of Aging and Human Development
Campus mail 2508 Busse Bldg, Durham, NC 27710
Phone (919) 660-7519
Email address bales001@mc.duke.edu

Research in our laboratory focuses on the role of nutrition (particularly vitamins and minerals) in the prevention and management of chronic diseases in older adults. Previous studies have concerned trace elements and cardiovascular disease, calcium and osteoporosis, and renal synthesis of vitamin D as it relates to bone health. Some of our newest work emphasizes the role of micronutrients as antioxidants and their interaction with the aging process. We are also working on various aspects of energy balance in older adults, ranging from failure to thrive in stroke patients with dysphagia to exercise and nutrition effects in overweight subjects who begin physical training. Thus we have a number of clinical and epidemiological projects on-going, many of which include a strong emphasis on nutrition assessment techniques in middle-aged and elderly subjects.

Education and Training

  • Ph.D., University of Tennessee at Knoxville, 1981

Publications

Huffman, K., M. Orenduff, G. P. Samsa, W. E. Kraus, and C. W. Bales. “Relationship of glycemic load to cardiovascular risk factors and high sensitivity C reactive protein (hsCRP) in sedentary men and women with the metabolic syndrome.” In Faseb Journal, 20:A579–A579. FEDERATION AMER SOC EXP BIOL, 2006.

Scholars@Duke

Slentz, Cris A., Lori B. Aiken, Joseph A. Houmard, Connie W. Bales, Johanna L. Johnson, Charles J. Tanner, Brian D. Duscha, and William E. Kraus. “Inactivity, exercise, and visceral fat. STRRIDE: a randomized, controlled study of exercise intensity and amount.” J Appl Physiol (1985) 99, no. 4 (October 2005): 1613–18. https://doi.org/10.1152/japplphysiol.00124.2005.

PMID
16002776
Full Text

Bales, C. W., and J. L. Purser. “Achieving a healthy body weight: Diet and exercise interventions for type 2 diabetes.” In Nutrition and Diabetes: Pathophysiology and Management, 43–56, 2005.

Scholars@Duke

White, Heidi K., Eleanor S. McConnell, Connie W. Bales, and Maragatha Kuchibhatla. “A 6-month observational study of the relationship between weight loss and behavioral symptoms in institutionalized Alzheimer's disease subjects.” J Am Med Dir Assoc 5, no. 2 (March 2004): 89–97. https://doi.org/10.1097/01.JAM.0000110646.48753.EF.

PMID
14984619
Full Text

Slentz, Cris A., Brian D. Duscha, Johanna L. Johnson, Kevin Ketchum, Lori B. Aiken, Gregory P. Samsa, Joseph A. Houmard, Connie W. Bales, and William E. Kraus. “Effects of the amount of exercise on body weight, body composition, and measures of central obesity: STRRIDE--a randomized controlled study.” Arch Intern Med 164, no. 1 (January 12, 2004): 31–39. https://doi.org/10.1001/archinte.164.1.31.

PMID
14718319
Full Text

Bales, C. W., J. G. Fischer, and M. C. Orenduff. “Nutritional interventions for age-related chronic disease.” Generations 28, no. 3 (January 1, 2004): 54–60.

Scholars@Duke

Kraus, William E., Joseph A. Houmard, Brian D. Duscha, Kenneth J. Knetzger, Michelle B. Wharton, Jennifer S. McCartney, Connie W. Bales, et al. “Effects of the amount and intensity of exercise on plasma lipoproteins.” N Engl J Med 347, no. 19 (November 7, 2002): 1483–92. https://doi.org/10.1056/NEJMoa020194.

PMID
12421890
Full Text

Bales, Connie W. “Alternative diet therapy for elderly patients. Unique concerns for a high-risk population.” Clin Geriatr Med 18, no. 4 (November 2002): 841–51. https://doi.org/10.1016/s0749-0690(02)00039-3.

PMID
12608508
Full Text

Bales, C. W., P. C. Moschella, C. Slentz, K. Knetzger, K. Ketchum, B. Duscha, G. Samsa, J. Houmard, and W. E. Kraus. “Sustained effects of chronic exercise on blood lipids in adults aged 40-65 years: The Studies of a Targeted Risk Reduction Intervention through Defined Exercise (STRIDDE) trial.” In Faseb Journal, 16:A241–A241. FEDERATION AMER SOC EXP BIOL, 2002.

Scholars@Duke

Pages