Daniel Christopher Parker, MD

Assistant Professor of Medicine
Assistant Professor in Neurology
Senior Fellow of the Center for the Study of Aging and Human Development
Campus mail Rm 1510 Blue Zone Duke South, Box 3003, Durham, NC 27705
Phone (919) 660-7692
Email address daniel.parker@duke.edu

Biological aging is the greatest risk factor for most chronic diseases, including frailty and dementia. The geroscience hypothesis posits that interventions that target aspects of biological aging may delay or prevent many of these diseases simultaneously. My research centers on understanding the mechanisms of interventions that affect biological aging, like exercise training and caloric restriction and using that understanding to develop therapies that maintain cognitive and physical function in older adults.

Education and Training

  • Post-Doctoral Research Fellowship, Duke Center For The Study Of Aging And Human Development, Duke University School of Medicine, 2017 - 2019
  • Internal Medicine Residency, Eastern Virginia Medical School, 2013 - 2016
  • Advanced Fellowship in Geriatric Medicine, Medicine, ,, 0018
  • M.D., Eastern Virginia Medical School, 2013

Publications

Ross, Leanna M., Roshan Tourani, Sisi Ma, Steven Shen, Daniel C. Parker, Kim M. Huffman, Virginia B. Kraus, Constantin F. Aliferis, and William E. Kraus. “Utilizing Causal Pathway Analysis To Predict Change In Cardiorespiratory Fitness In The STRRIDE Randomized Trials.” In Medicine and Science in Sports and Exercise, 52:503–503, 2020.

Scholars@Duke

Parker, D. C., C. Colon-Emeric, and K. Huffman. “Biomarkers of Metabolic Dysregulation, Inflammation, and Cellular Senescence are Associated with Impaired Physical Resilience After Hip Fracture.” In Journal of the American Geriatrics Society, 68:S7–S7. WILEY, 2020.

Scholars@Duke

Parker, D., R. Faldowski, M. Morey, R. Sloane, C. Pieper, K. Hall, and H. J. Cohen. “Association of Plasma Biomarkers of Alzheimer's Disease and Neurodegeneration with Physical Performance in Older Adults without Dementia.” In Journal of the American Geriatrics Society, 70:S11–S11, 2020.

Scholars@Duke

Parker, D., S. McDonald, K. Starr, D. Blazer, A. Kirk, and S. Lagoo-Deenadayalan. “Pre-Operative Biological Age Advancement is Associated with Longer Post-Operative Length of Stay.” In Journal of the American Geriatrics Society, 70:S137–S137, 2020.

Scholars@Duke

Colón-Emeric, Cathleen, Heather E. Whitson, Carl F. Pieper, Richard Sloane, Denise Orwig, Kim M. Huffman, Janet Prvu Bettger, et al. “Resiliency Groups Following Hip Fracture in Older Adults.” J Am Geriatr Soc 67, no. 12 (December 2019): 2519–27. https://doi.org/10.1111/jgs.16152.

PMID
31469411
Full Text

Parker, D. C., W. E. Kraus, C. Pieper, H. J. Cohen, and K. M. Huffman. “Data-Driven Cluster Analysis Identifies Unique Inflammatory and Metabolic Signatures Associated with Self-Rated Health, Cognitive Performance, and Function.” In Journal of the American Geriatrics Society, 67:S10–S10. WILEY, 2019.

Scholars@Duke

Parker, D. C., J. Counts, G. Upchurch, M. Krol, and M. Heflin. “Evaluation of an Online Community Resource Referral Platform for Older Adults.” In Journal of the American Geriatrics Society, 67:S37–S37. WILEY, 2019.

Scholars@Duke

Parker, D. C., D. W. Belsky, and V. B. Kraus. “Quantifications of biological aging predict disability and mortality in older adults in the Duke EPESE.” In Journal of the American Geriatrics Society, 67:S145–S145. WILEY, 2019.

Scholars@Duke

Parker, Daniel, Richard Sloane, Carl F. Pieper, Katherine S. Hall, Virginia B. Kraus, William E. Kraus, Janet L. Huebner, et al. “Age-Related Adverse Inflammatory and Metabolic Changes Begin Early in Adulthood.” J Gerontol a Biol Sci Med Sci 74, no. 3 (February 15, 2019): 283–89. https://doi.org/10.1093/gerona/gly121.

PMID
29985987
Full Text

Zhou, Jin, Daniel C. Parker, James P. White, Andrea Lim, Kim M. Huffman, Jia Pei Ho, Paul M. Yen, and William E. Kraus. “Thyroid Hormone Status Regulates Skeletal Muscle Response to Chronic Motor Nerve Stimulation.” Front Physiol 10 (2019): 1363. https://doi.org/10.3389/fphys.2019.01363.

PMID
31736784
Full Text

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