Endocrinology, Metabolism, and Nutrition

David A D'Alessio, MD

Professor of Medicine
Chief, Division of Endocrinology and Metabolism
Member of Duke Molecular Physiology Institute
Campus mail 300 North Duke Street, Durham, NC 27701
Phone (919) 684-4005
Email address david.d'alessio@duke.edu

Education and Training

  • Research Fellowship, Metabolism, Endocrinology And Nutrition, University of Washington School of Medicine, 1987 - 1990
  • Resident, Temple University School of Medicine, 1983 - 1986
  • M.D., University of Wisconsin at Madison, 1983

Grants

Publications

Koska, J, Sands, M, Burciu, C, D'Souza, KM, Raravikar, K, Liu, J, Truran, S, Franco, DA, Schwartz, EA, Schwenke, DC, D'Alessio, D, Migrino, RQ, and Reaven, PD. "Exenatide Protects Against Glucose- and Lipid-Induced Endothelial Dysfunction: Evidence for Direct Vasodilation Effect of GLP-1 Receptor Agonists in Humans." Diabetes 64, no. 7 (July 2015): 2624-2635.

PMID
25720388
Full Text

Aulinger, BA, Vahl, TP, Wilson-Pérez, HE, Prigeon, RL, and D'Alessio, DA. "β-Cell Sensitivity to GLP-1 in Healthy Humans Is Variable and Proportional to Insulin Sensitivity." The Journal of Clinical Endocrinology and Metabolism 100, no. 6 (June 2015): 2489-2496.

PMID
25825945
Full Text

Müller, TD, Nogueiras, R, Andermann, ML, Andrews, ZB, Anker, SD, Argente, J, Batterham, RL, Benoit, SC, Bowers, CY, Broglio, F, Casanueva, FF, D'Alessio, D, Depoortere, I, Geliebter, A, Ghigo, E, Cole, PA, Cowley, M, Cummings, DE, Dagher, A, Diano, S, Dickson, SL, Diéguez, C, Granata, R, Grill, HJ, Grove, K, Habegger, KM, Heppner, K, Heiman, ML, Holsen, L, Holst, B, Inui, A, Jansson, JO, Kirchner, H, Korbonits, M, Laferrère, B, LeRoux, CW, Lopez, M, Morin, S, Nakazato, M, Nass, R, Perez-Tilve, D, Pfluger, PT, Schwartz, TW, Seeley, RJ, Sleeman, M, Sun, Y, Sussel, L, Tong, J, Thorner, MO, van der Lely, AJ, van der Ploeg, LHT, Zigman, JM, Kojima, M, Kangawa, K, Smith, RG, Horvath, T, and Tschöp, MH. "Ghrelin." Molecular Metabolism 4, no. 6 (June 2015): 437-460. (Review)

PMID
26042199
Full Text

Ottaway, N, Mahbod, P, Rivero, B, Norman, LA, Gertler, A, D'Alessio, DA, and Perez-Tilve, D. "Diet-induced obese mice retain endogenous leptin action." Cell Metabolism 21, no. 6 (June 2015): 877-882.

PMID
25980347
Full Text

Sandoval, DA, and D'Alessio, DA. "Physiology of proglucagon peptides: role of glucagon and GLP-1 in health and disease." Physiological Reviews 95, no. 2 (April 2015): 513-548. (Review)

PMID
25834231
Full Text

Elder, DA, Hornung, LN, Herbers, PM, Prigeon, R, Woo, JG, and D'Alessio, DA. "Rapid deterioration of insulin secretion in obese adolescents preceding the onset of type 2 diabetes." The Journal of Pediatrics 166, no. 3 (March 2015): 672-678.

PMID
25557969
Full Text

D'Alessio, D, Häring, H-U, Charbonnel, B, de Pablos-Velasco, P, Candelas, C, Dain, M-P, Vincent, M, Pilorget, V, Yki-Järvinen, H, and EAGLE Investigators, . "Comparison of insulin glargine and liraglutide added to oral agents in patients with poorly controlled type 2 diabetes." Diabetes, obesity & metabolism 17, no. 2 (February 2015): 170-178.

PMID
25359159
Full Text

Tong, J, and D'Alessio, D. "Ghrelin and hypothalamic development: too little and too much of a good thing." The Journal of Clinical Investigation 125, no. 2 (February 2015): 490-492.

PMID
25607837
Full Text

Elder, DA, Hornung, LN, Herbers, PM, Prigeon, R, Woo, JG, and D'Alessio, DA. "Rapid deterioration of insulin secretion in obese adolescents preceding the onset of type 2 diabetes." Journal of Pediatrics 166, no. 3 (January 1, 2015): 672-678.

Full Text

Vahl, TP, Aulinger, BA, Smith, EP, Drazen, DL, Ulrich-Lai, Y, Seeley, RJ, Woods, SC, and D'Alessio, DA. "Meal feeding improves oral glucose tolerance in male rats and causes adaptations in postprandial islet hormone secretion that are independent of plasma incretins or glycemia." American Journal of Physiology. Endocrinology and Metabolism 307, no. 9 (November 2014): E784-E792.

PMID
25159330
Full Text

Pages