Endocrinology, Metabolism, and Nutrition

David A D'Alessio, MD

Professor of Medicine
Chief, Division of Endocrinology and Metabolism
Member of Duke Molecular Physiology Institute
Campus mail 300 North Duke Street, Durham, NC 27701
Phone (919) 684-4005
Email address david.d'alessio@duke.edu

Education and Training

  • Research Fellowship, Metabolism, Endocrinology And Nutrition, University of Washington School of Medicine, 1987 - 1990
  • Resident, Temple University School of Medicine, 1983 - 1986
  • M.D., University of Wisconsin at Madison, 1983

Grants

Publications

Smith, EP, An, Z, Wagner, C, Lewis, AG, Cohen, EB, Li, B, Mahbod, P, Sandoval, D, Perez-Tilve, D, Tamarina, N, Philipson, LH, Stoffers, DA, Seeley, RJ, and D'Alessio, DA. "The role of β cell glucagon-like peptide-1 signaling in glucose regulation and response to diabetes drugs." Cell Metabolism 19, no. 6 (June 2014): 1050-1057.

PMID
24836562
Full Text

Salehi, M, Gastaldelli, A, and D'Alessio, DA. "Beta-Cell Response to Graded up & Down Glucose Infusion after Gastric Bypass Surgery." ENDOCRINE REVIEWS 35, no. 3 (June 2014).

Scholars@Duke

Salehi, M, Gastaldelli, A, and D'Alessio, DA. "Altered islet function and insulin clearance cause hyperinsulinemia in gastric bypass patients with symptoms of postprandial hypoglycemia." The Journal of Clinical Endocrinology and Metabolism 99, no. 6 (June 2014): 2008-2017.

PMID
24617664
Full Text

Sisley, S, Gutierrez-Aguilar, R, Scott, M, D'Alessio, DA, Sandoval, DA, and Seeley, RJ. "Neuronal GLP1R mediates liraglutide's anorectic but not glucose-lowering effect." The Journal of Clinical Investigation 124, no. 6 (June 2014): 2456-2463.

PMID
24762441
Full Text

Gastaldelli, A, Brodows, RG, and D'Alessio, D. "The effect of chronic twice daily exenatide treatment on β-cell function in new onset type 2 diabetes." Clinical endocrinology 80, no. 4 (April 2014): 545-553.

PMID
23574529
Full Text

Salehi, M, Gastaldelli, A, and D'Alessio, DA. "Blockade of glucagon-like peptide 1 receptor corrects postprandial hypoglycemia after gastric bypass." Gastroenterology 146, no. 3 (March 2014): 669-680.e2.

PMID
24315990
Full Text

Chambers, AP, Smith, EP, Begg, DP, Grayson, BE, Sisley, S, Greer, T, Sorrell, J, Lemmen, L, LaSance, K, Woods, SC, Seeley, RJ, D'Alessio, DA, and Sandoval, DA. "Regulation of gastric emptying rate and its role in nutrient-induced GLP-1 secretion in rats after vertical sleeve gastrectomy." American Journal of Physiology. Endocrinology and Metabolism 306, no. 4 (February 2014): E424-E432.

PMID
24368666
Full Text

Habegger, KM, Heppner, KM, Amburgy, SE, Ottaway, N, Holland, J, Raver, C, Bartley, E, Müller, TD, Pfluger, PT, Berger, J, Toure, M, Benoit, SC, Dimarchi, RD, Perez-Tilve, D, D'Alessio, DA, Seeley, RJ, and Tschöp, MH. "GLP-1R responsiveness predicts individual gastric bypass efficacy on glucose tolerance in rats." Diabetes 63, no. 2 (February 2014): 505-513.

PMID
24186863
Full Text

Gutierrez-Aguilar, R, Kim, D-H, Casimir, M, Dai, X-Q, Pfluger, PT, Park, J, Haller, A, Donelan, E, Park, J, D'Alessio, D, Woods, SC, MacDonald, PE, and Seeley, RJ. "The role of the transcription factor ETV5 in insulin exocytosis." Diabetologia 57, no. 2 (February 2014): 383-391.

PMID
24190582
Full Text

Tong, J, and D'Alessio, D. "Give the receptor a brake: slowing gastric emptying by GLP-1." Diabetes 63, no. 2 (February 2014): 407-409.

PMID
24464721
Full Text

Pages