David A D'Alessio, MD

Professor of Medicine
Chief, Division of Endocrinology and Metabolism
Member of Duke Molecular Physiology Institute
Campus mail 300 North Duke Street, Durham, NC 27701
Phone (919) 684-4005
Email address david.d'alessio@duke.edu

Education and Training

  • Research Fellowship, Metabolism, Endocrinology And Nutrition, University of Washington School of Medicine, 1987 - 1990
  • Resident, Temple University School of Medicine, 1983 - 1986
  • M.D., University of Wisconsin at Madison, 1983

Publications

Mahbod, P, Smith, E, Wagner, C, Lewis, AG, Benoit, SC, Elmquist, JK, Zigman, JM, D'Alessio, DA, and Tong, J. "Ghrelin Signaling in the Central Nervous System and/or beta-Cells Is Important for the Regulation of Insulin Secretion and Glucose Tolerance in Mice." DIABETES 62 (July 2013): A511-A511.

Scholars@Duke

Tong, J, Dave, N, Mugundu, GM, Davis, HW, Gaylinn, BD, Thorner, MO, Tschöp, MH, D'Alessio, D, and Desai, PB. "The pharmacokinetics of acyl, des-acyl, and total ghrelin in healthy human subjects." European journal of endocrinology 168, no. 6 (June 2013): 821-828.

PMID
23482590
Full Text

Tong, J, Prigeon, RL, Davis, HW, Bidlingmaier, M, Tschöp, MH, and D'Alessio, D. "Physiologic concentrations of exogenously infused ghrelin reduces insulin secretion without affecting insulin sensitivity in healthy humans." The Journal of clinical endocrinology and metabolism 98, no. 6 (June 2013): 2536-2543.

PMID
23589527
Full Text

Habegger, KM, Stemmer, K, Cheng, C, Müller, TD, Heppner, KM, Ottaway, N, Holland, J, Hembree, JL, Smiley, D, Gelfanov, V, Krishna, R, Arafat, AM, Konkar, A, Belli, S, Kapps, M, Woods, SC, Hofmann, SM, D'Alessio, D, Pfluger, PT, Perez-Tilve, D, Seeley, RJ, Konishi, M, Itoh, N, Kharitonenkov, A, Spranger, J, DiMarchi, RD, and Tschöp, MH. "Fibroblast growth factor 21 mediates specific glucagon actions." Diabetes 62, no. 5 (May 2013): 1453-1463.

PMID
23305646
Full Text

Begg, DP, Mul, JD, Liu, M, Reedy, BM, D'Alessio, DA, Seeley, RJ, and Woods, SC. "Reversal of diet-induced obesity increases insulin transport into cerebrospinal fluid and restores sensitivity to the anorexic action of central insulin in male rats." Endocrinology 154, no. 3 (March 2013): 1047-1054.

PMID
23337529
Full Text

Cummings, BP, Bremer, AA, Kieffer, TJ, D'Alessio, D, and Havel, PJ. "Investigation of the mechanisms contributing to the compensatory increase in insulin secretion during dexamethasone-induced insulin resistance in rhesus macaques." The Journal of endocrinology 216, no. 2 (February 2013): 207-215.

PMID
23151361
Full Text

Jessen, L, Aulinger, BA, Hassel, JL, Roy, KJ, Smith, EP, Greer, TM, Woods, SC, Seeley, RJ, and D'Alessio, DA. "Suppression of food intake by glucagon-like peptide-1 receptor agonists: relative potencies and role of dipeptidyl peptidase-4." Endocrinology 153, no. 12 (December 2012): 5735-5745.

PMID
23033273
Full Text

Salehi, M, Aulinger, B, and D'Alessio, DA. "Effect of glycemia on plasma incretins and the incretin effect during oral glucose tolerance test." Diabetes 61, no. 11 (November 2012): 2728-2733.

PMID
22733799
Full Text

Chambers, AP, Wilson-Perez, HE, McGrath, S, Grayson, BE, Ryan, KK, D'Alessio, DA, Woods, SC, Sandoval, DA, and Seeley, RJ. "Effect of vertical sleeve gastrectomy on food selection and satiation in rats." American journal of physiology. Endocrinology and metabolism 303, no. 8 (October 2012): E1076-E1084.

PMID
22932782
Full Text

Tong, J, D'Alessio, D, Ramisch, J, Davis, HW, Stambrook, E, Tschöp, MH, and Bidlingmaier, M. "Ghrelin stimulation of growth hormone isoforms: parallel secretion of total and 20-kDa growth hormone and relation to insulin sensitivity in healthy humans." The Journal of clinical endocrinology and metabolism 97, no. 9 (September 2012): 3366-3374.

PMID
22745239
Full Text

Pages