David A D'Alessio, MD

Professor of Medicine
Chief, Division of Endocrinology and Metabolism
Member of Duke Molecular Physiology Institute
Campus mail 300 North Duke Street, Durham, NC 27701
Phone (919) 684-4005
Email address david.d'alessio@duke.edu

Education and Training

  • Research Fellowship, Metabolism, Endocrinology And Nutrition, University of Washington, School of Medicine, 1987 - 1990
  • Resident, Temple University, School of Medicine, 1983 - 1986
  • M.D., University of Wisconsin - Madison, 1983

Publications

Inge, Thomas H., Ronald L. Prigeon, Deborah A. Elder, Todd M. Jenkins, Robert M. Cohen, Stavra A. Xanthakos, Stephen C. Benoit, Lawrence M. Dolan, Stephen R. Daniels, and David A. D’Alessio. “Insulin Sensitivity and β-Cell Function Improve after Gastric Bypass in Severely Obese Adolescents.” J Pediatr 167, no. 5 (November 2015): 1042-8.e1. https://doi.org/10.1016/j.jpeds.2015.08.020.

PMID
26363548
Full Text

Ghosal, Sriparna, Amanda Nunley, Parinaz Mahbod, Alfor G. Lewis, Eric P. Smith, Jenny Tong, David A. D’Alessio, and James P. Herman. “Mouse handling limits the impact of stress on metabolic endpoints.” Physiol Behav 150 (October 15, 2015): 31–37. https://doi.org/10.1016/j.physbeh.2015.06.021.

PMID
26079207
Full Text

Salehi, Marzieh, Stephen C. Woods, and David A. D’Alessio. “Gastric bypass alters both glucose-dependent and glucose-independent regulation of islet hormone secretion.” Obesity (Silver Spring) 23, no. 10 (October 2015): 2046–52. https://doi.org/10.1002/oby.21186.

PMID
26316298
Full Text

Begg, Denovan P., Aaron A. May, Joram D. Mul, Min Liu, David A. D’Alessio, Randy J. Seeley, and Stephen C. Woods. “Insulin Detemir Is Transported From Blood to Cerebrospinal Fluid and Has Prolonged Central Anorectic Action Relative to NPH Insulin.” Diabetes 64, no. 7 (July 2015): 2457–66. https://doi.org/10.2337/db14-1364.

PMID
25667307
Full Text

Beamish, Andrew J., David A. D’Alessio, and Thomas H. Inge. “Controversial Issues: When the drugs don't work, can surgery provide a different outcome for diabetic adolescents?” Surg Obes Relat Dis 11, no. 4 (July 2015): 946–48. https://doi.org/10.1016/j.soard.2015.03.006.

PMID
25980332
Full Text

Tong, Jenny, and David D’Alessio. “Surgical Treatment of Diabetes: Making a Case for a Pragmatic Approach.” J Clin Endocrinol Metab 100, no. 7 (July 2015): 2536–38. https://doi.org/10.1210/jc.2015-2551.

PMID
26151399
Full Text

Rosario, Wilfredo, and David D’Alessio. “An Innate Disposition for a Healthier Gut: GLP-1R Signaling in Intestinal Epithelial Lymphocytes.” Diabetes 64, no. 7 (July 2015): 2329–31. https://doi.org/10.2337/db15-0436.

PMID
26106193
Full Text

Koska, Juraj, Michelle Sands, Camelia Burciu, Karen M. D’Souza, Kalyani Raravikar, James Liu, Seth Truran, et al. “Exenatide Protects Against Glucose- and Lipid-Induced Endothelial Dysfunction: Evidence for Direct Vasodilation Effect of GLP-1 Receptor Agonists in Humans.” Diabetes 64, no. 7 (July 2015): 2624–35. https://doi.org/10.2337/db14-0976.

PMID
25720388
Full Text

Ottaway, Nickki, Parinaz Mahbod, Belen Rivero, Lee Ann Norman, Arieh Gertler, David A. D’Alessio, and Diego Perez-Tilve. “Diet-induced obese mice retain endogenous leptin action.” Cell Metab 21, no. 6 (June 2, 2015): 877–82. https://doi.org/10.1016/j.cmet.2015.04.015.

PMID
25980347
Full Text

Aulinger, Benedikt A., Torsten P. Vahl, Hilary E. Wilson-Pérez, Ron L. Prigeon, and David A. D’Alessio. “β-Cell Sensitivity to GLP-1 in Healthy Humans Is Variable and Proportional to Insulin Sensitivity.” J Clin Endocrinol Metab 100, no. 6 (June 2015): 2489–96. https://doi.org/10.1210/jc.2014-4009.

PMID
25825945
Full Text

Pages