David James Easterhoff, PhD

Publications

Bonsignori, Mattia, Eric Scott, Kevin Wiehe, David Easterhoff, S Munir Alam, Kwan-Ki Hwang, Melissa Cooper, et al. “Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier..” Immunity 49, no. 6 (December 18, 2018): 1162-1174.e8. https://doi.org/10.1016/j.immuni.2018.10.015.

PMID
30552024
Full Text

Williams, LaTonya, Matthew Zirui Tay, Xiaoying Shen, Sheetal Sawant, Lindsay Dahora, Nicole Yates, David Easterhoff, et al. “Delayed and Repetitive Boosting of RV144 Vaccinees Improves Antiviral Immunity Associated With Correlates of HIV-1 Infection Risk.” In Aids Research and Human Retroviruses, 34:88–88. MARY ANN LIEBERT, INC, 2018.

Scholars@Duke

Peachman, Kristina, David Easterhoff, Siriwat Akapirat, Supachai Rerks-Ngarm, Punnee Pittisuttithum, Sorachai Nitayaphan, Sanjay Phogat, et al. “Prolonged Intervals Between Boosts Induces High Magnitude Transient V2-specific Functional Antibodies That Inhibit the Binding of V2 to alpha 4 beta 7 Integrin.” In Aids Research and Human Retroviruses, 34:127–127. MARY ANN LIEBERT, INC, 2018.

Scholars@Duke

Bonsignori, Mattia, Eric Scott, Kevin Wiehe, David Easterhoff, S Munir Alam, Kwan-Ki Hwang, David C. Montefiori, et al. “Dual Maturation Pathways from the Unmutated Common Ancestor of HIV-1 Envelope Broadly Neutralizing Antibodies Overcome Glycan Barriers.” In Aids Research and Human Retroviruses, 34:111–111. MARY ANN LIEBERT, INC, 2018.

Scholars@Duke

Wiehe, Kevin, Todd Bradley, R Ryan Meyerhoff, Connor Hart, Wilton B. Williams, David Easterhoff, William J. Faison, et al. “Functional Relevance of Improbable Antibody Mutations for HIV Broadly Neutralizing Antibody Development..” Cell Host Microbe 23, no. 6 (June 13, 2018): 759-765.e6. https://doi.org/10.1016/j.chom.2018.04.018.

PMID
29861171
Full Text

Ding, Shilei, Myriam M. Verly, Amy Princiotto, Bruno Melillo, Anthony M. Moody, Todd Bradley, David Easterhoff, et al. “Short Communication: Small-Molecule CD4 Mimetics Sensitize HIV-1-Infected Cells to Antibody-Dependent Cellular Cytotoxicity by Antibodies Elicited by Multiple Envelope Glycoprotein Immunogens in Nonhuman Primates..” Aids Res Hum Retroviruses 33, no. 5 (May 2017): 428–31. https://doi.org/10.1089/AID.2016.0246.

PMID
27846736
Full Text

Easterhoff, David, M Anthony Moody, Daniela Fera, Hao Cheng, Margaret Ackerman, Kevin Wiehe, Kevin O. Saunders, et al. “Boosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial..” Plos Pathog 13, no. 2 (February 2017). https://doi.org/10.1371/journal.ppat.1006182.

PMID
28235027
Full Text

Luo, Kan, Hua-Xin Liao, Ruijun Zhang, David Easterhoff, Kevin Wiehe, Thaddeus C. Gurley, Lawrence C. Armand, et al. “Tissue memory B cell repertoire analysis after ALVAC/AIDSVAX B/E gp120 immunization of rhesus macaques..” Jci Insight 1, no. 20 (December 8, 2016). https://doi.org/10.1172/jci.insight.88522.

PMID
27942585
Full Text

Madani, Navid, Amy Princiotto, David Easterhoff, Todd Bradley, Kan Luo, M Anthony Moody, Ganesh Phad, et al. “Prevention of Vaginal Transmission of Simian-Human Immunodeficiency Virus (SHIV) in Rhesus Monkeys by Small-molecule CD4-mimetic Compounds.” In Aids Research and Human Retroviruses, 32:129–129. MARY ANN LIEBERT, INC, 2016.

Scholars@Duke

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