David Lee Simel, MD

Professor of Medicine
Vice-Chair for Veterans Affairs in the Department of Medicine
Campus mail Room C8010, Durham VA Med Ct., 508 Fulton St, Durham, NC 27705
Phone (919) 286-6941
Email address david.simel@duke.edu

Chief, Medical Service, Durham Veterans Affairs Medical Center

Appropriateness of diagnostic test use, including not just traditional laboratory and radiographic tests, but also the clinical examination. Editor of the "Rational Clinical Examination Series" published in the Journal of the American Medical Association.

Metaanalysis of diagnostic test studies

Education and Training

  • Fellowship in Hematology-Oncology, Medicine, Duke University, 1985 - 1986
  • Chief Medical Resident, Medicine, Duke University, 1984 - 1985
  • Medical Resident, Medicine, Duke University, 1981 - 1984
  • Fellowship in Hematology-Oncology, Medicine, Duke University, 1981 - 1981
  • M.S., Duke University, 1990
  • M.D., Duke University, 1980


Bedlack, R. S., D. L. Simel, H. Bosworth, G. Samsa, B. Tucker-Lipscomb, and D. B. Sanders. “Quantitative myasthenia gravis score: assessment of responsiveness and longitudinal validity.” Neurology 64, no. 11 (June 14, 2005): 1968–70. https://doi.org/10.1212/01.WNL.0000163988.28892.79.

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Call, Stephanie A., Mark A. Vollenweider, Carlton A. Hornung, David L. Simel, and W Paul McKinney. “Does this patient have influenza?” Jama 293, no. 8 (February 23, 2005): 987–97. https://doi.org/10.1001/jama.293.8.987.

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Rothman, R., D. L. Simel, and M. Uhari. “Review: Ear pain and a cloudy, bulging, or distinctly immobile tympanic membrane appear to help diagnose acute otitis media in children.” Evidence Based Medicine 9, no. 2 (March 1, 2004): 58. https://doi.org/10.1136/ebm.9.2.58.

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Whited, John D., Russell P. Hall, Marjorie E. Foy, Laurie E. Marbrey, Steven C. Grambow, Tara K. Dudley, Santanu K. Datta, David L. Simel, and Eugene Z. Oddone. “Patient and clinician satisfaction with a store-and-forward teledermatology consult system.” Telemed J E Health 10, no. 4 (2004): 422–31. https://doi.org/10.1089/tmj.2004.10.422.

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Chunilal, Sanjeev D., John W. Eikelboom, John Attia, Massimo Miniati, Akbar A. Panju, David L. Simel, and Jeffrey S. Ginsberg. “Does this patient have pulmonary embolism?” Jama 290, no. 21 (December 3, 2003): 2849–58. https://doi.org/10.1001/jama.290.21.2849.

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Fowler, Vance G., Keith S. Kaye, David L. Simel, Christopher H. Cabell, Douglas McClachlan, Peter K. Smith, Scott Levin, et al. “Staphylococcus aureus bacteremia after median sternotomy: clinical utility of blood culture results in the identification of postoperative mediastinitis.” Circulation 108, no. 1 (July 8, 2003): 73–78. https://doi.org/10.1161/01.CIR.0000079105.65762.DB.

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Rothman, R. L., T. A. Owens, and D. L. Simel. “"Does this child have Acute Otitis Media (AOM)?" - An evidence-based appraisal of clinical diagnosis.” In Pediatric Research, 53:251A-251A. INT PEDIATRIC RESEARCH FOUNDATION, INC, 2003.