Eric J. Velazquez, MD

Professor of Medicine
Affiliate, Duke Global Health Institute
Member in the Duke Clinical Research Institute
Campus mail 2400 Pratt St, Durham, NC 27705
Phone (919) 668-8700
Email address

Eric J. Velazquez, MD, is a Professor of Medicine with tenure at Duke University.  As section chief for Cardiovascular Imaging in the Division of Cardiology and director of the Cardiac Diagnostic Unit and Echocardiography Laboratories for Duke University Health System, he coordinates a high-volume enterprise and an outstanding group of clinician-investigators and clinical staff who make important contributions across patient care, research and educational domains.  A long-time faculty leader in the Duke Clinical Research Institute, he manages its portfolio of government-funded clinical trials.  Dr. Velazquez is a member of the Duke Global Health Institute and leads the university’s cardiovascular global health efforts.  He serves on several institutional committees and is an Associate Director of the Duke Heart Center.

Dr. Velazquez received his medical degree from the Albert Einstein College of Medicine of Yeshiva University in New York.  He completed a residency in Internal Medicine and fellowships in clinical cardiology, clinical research and echocardiography at Duke University Medical Center.  He served as a visiting registrar at Oxford University’s John Radcliffe Hospital and joined Duke’s Department of Medicine faculty in 2001 where he was named the Joseph Greenfield Scholar in Cardiology. Dr. Velazquez is board certified in Cardiovascular Diseases and is a Fellow in the American College of Cardiology, American College of Physicians, American Society of Echocardiography and American Heart Association.  He is a globally recognized authority on heart failure, cardiovascular clinical trials and cardiac imaging.

Clinical Research
Dr. Velazquez’s research comprises the evaluation and management of heart failure, particularly with coronary artery disease, hypertension, valve and ischemic heart disease, global clinical trials and cardiovascular imaging.  He has led numerous global clinical trials including STICH, the landmark study of surgical treatment for ischemic heart failure, VALIANT, ACCOMPLISH and the Heart Failure Network.  As principal investigator, he led an NHLBI-funded Global Health Program for Chronic Cardiovascular Diseases in Eldoret, Kenya which established the first intensive cardiac care and training program in Western Kenya.  Currently he is principal investigator for the NHLBI-funded STICHES Program.  Dr. Velazquez directs the Duke Echo Lab Database, one of the world’s largest digital repositories with over 200,000 images, and leads research to expand understanding of heart disease and imaging techniques.

In 2014, Dr. Velazquez was inducted into the American Society of Clinical Investigation, an honor society dedicated to advancing research, translating findings into clinical practice and mentoring future generations of physician-scientists.  He has co-authored over 250 peer-reviewed publications, including recent manuscripts in the New England Journal of Medicine, Journal of the American Medical Association, Circulation and European Heart Journal.  He has served as Chair of the American Society of Echocardiography Taskforce on International Echocardiography.  A dedicated mentor, Dr. Velazquez has guided numerous physician-scientists, cardiology fellows, medical students and health care professionals in building unique careers and providing outstanding patient care through clinical, academic and research excellence.

In Their Words

Education and Training

  • Research Fellow, Medicine/Echocardiography Laboratory, Duke University, 1999 - 2001
  • Clinical Research Fellow, Medicine/Dcri, Duke University, 1999 - 2001
  • Clinical Cardiology Fellow, Medicine, Duke University, 1997 - 2001
  • Medical Resident, Medicine, Duke University, 1994 - 1997
  • M.D., Yeshiva University New York, 1994


Velazquez, EJ, Morrow, DA, DeVore, AD, Ambrosy, AP, Duffy, CI, McCague, K, Hernandez, AF, Rocha, RA, and Braunwald, E. "Rationale and design of the comParIson Of sacubitril/valsartaN versus Enalapril on Effect on nt-pRo-bnp in patients stabilized from an acute Heart Failure episode (PIONEER-HF) trial." American Heart Journal 198 (April 1, 2018): 145-151.

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Agarwal, A, Kirwa, K, Eliot, MN, Alenezi, F, Menya, D, Mitter, SS, Velazquez, EJ, Vedanthan, R, Wellenius, GA, and Bloomfield, GS. "Household Air Pollution Is Associated with Altered Cardiac Function among Women in Kenya." American journal of respiratory and critical care medicine 197, no. 7 (April 2018): 958-961.

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Butler, J, Kalogeropoulos, AP, Anstrom, KJ, Hsue, PY, Kim, RJ, Scherzer, R, Shah, SJ, Shah, SH, Velazquez, EJ, Hernandez, AF, Desvigne-Nickens, P, and Braunwald, E. "Diastolic Dysfunction in Individuals With Human Immunodeficiency Virus Infection: Literature Review, Rationale and Design of the Characterizing Heart Function on Antiretroviral Therapy (CHART) Study." Journal of cardiac failure 24, no. 4 (April 2018): 255-265.

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Sze, E, Samad, Z, Dunning, A, Campbell, KB, Loring, Z, Atwater, BD, Chiswell, K, Kisslo, JA, Velazquez, EJ, and Daubert, JP. "Impaired Recovery of Left Ventricular Function in Patients With Cardiomyopathy and Left Bundle Branch Block (vol 71, pg 306, 2018)." JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 71, no. 11 (March 20, 2018): 1296-1296.


Il'Giovine, ZJ, Mulder, H, Chiswell, K, Arges, K, Tomfohr, J, Hashmi, A, Velazquez, EJ, Kisslo, JA, Samad, Z, and Rajagopal, S. "Right Ventricular Longitudinal Strain Reproducibility Using Vendor-Dependent and Vendor-Independent Software." Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography (March 7, 2018).

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Pokorney, SD, Al-Khatib, SM, Sun, J-L, Schulte, P, O'Connor, CM, Teerlink, JR, Armstrong, PW, Ezekowitz, JA, Starling, RC, Voors, AA, Velazquez, EJ, Hernandez, AF, and Mentz, RJ. "Sudden cardiac death after acute heart failure hospital admission: insights from ASCEND-HF." March 2018.

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Piña, IL, Zheng, Q, She, L, Szwed, H, Lang, IM, Farsky, PS, Castelvecchio, S, Biernat, J, Paraforos, A, Kosevic, D, Favaloro, LE, Nicolau, JC, Varadarajan, P, Velazquez, EJ, Pai, RG, Cyrille, N, Lee, KL, Desvigne-Nickens, P, and STICH Trial Investigators, . "Sex Difference in Patients With Ischemic Heart Failure Undergoing Surgical Revascularization: Results From the STICH Trial (Surgical Treatment for Ischemic Heart Failure)." Circulation 137, no. 8 (February 2018): 771-780.

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Velazquez, EJ, and Petrie, MC. "CABG or PCI for Diabetic Patients With Left Ventricular Dysfunction: Closing in on the Truth?." Journal of the American College of Cardiology 71, no. 8 (February 2018): 828-831.

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Stewart, RAH, Szalewska, D, Stebbins, A, Al-Khalidi, HR, Cleland, JGH, Rynkiewicz, A, Drazner, MH, White, HD, Mark, DB, Roy, A, Kosevic, D, Rajda, M, Jasinski, M, Leng, CY, Tungsubutra, W, Desvigne-Nickens, P, Velazquez, EJ, and Petrie, MC. "Six-minute walk distance after coronary artery bypass grafting compared with medical therapy in ischaemic cardiomyopathy." Open heart 5, no. 1 (January 2018): e000752-.

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Brook, RD, Kaciroti, N, Bakris, G, Dahlöf, B, Pitt, B, Velazquez, E, Weber, M, Zappe, DH, Hau, T, and Jamerson, KA. "Prior medications and the cardiovascular benefits from combination angiotensin-converting enzyme inhibition plus calcium channel blockade among high-risk hypertensive patients." Journal of the American Heart Association 7, no. 1 (January 1, 2018).

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