Eric Leo Eisenstein

Associate Professor in Medicine
Associate Professor in Family Medicine and Community Health
Member in the Duke Clinical Research Institute
Campus mail 2400 Pratt St, Durham, NC 27705
Phone (919) 668-8984
Email address eisen006@mc.duke.edu

Research Interests:

Dr. Eisenstein is a member of the Duke Clinical Research Institute’s Outcomes Research and Assessment Group, with a special interest in understanding the relationships between complex interventions in health care systems and the long-term clinical and economic outcomes of patients. He has served as Principal Investigator for phase II, III, and IV economic and quality of life studies conducted alongside randomized clinical trials in cardiovascular, emergency, pulmonary, and vascular medicine and surgery. He also has conducted health technology evaluations making use of innovative research methods designed to better understand key relationships in observation (non-randomized) patient data. This work has included evaluations of the long-term clinical outcomes of coronary artery disease patients receiving drug-eluting vs. bare metal intracoronary stents, and how the use of clopidogrel changes those relationships. He also has conducted several studies assessing factors contributing to the costs of and evaluating different design considerations for multi-center randomized clinical trials.

In addition to his working in traditional health technology evaluation, Dr. Eisenstein has an interest in evaluating information technologies as interventions in health care systems. In this regard, he has collaborated in the design and conduct of large-scale, randomized clinical trials to evaluate clinical decision support systems. The research objective in these studies has been to develop methods for evaluating health information technologies in practice-based settings using a “tool kit” of inexpensive, yet highly scalable methods that make use of data sets created as a byproduct of normal clinical and administrative operations. The use of these evaluation methods has been demonstrated in four clinical trials that include care process, clinical, economic, and quality of life measurements.

Education and Training

  • D.B.A., Cleveland State University, 1995

Publications

Bacharova, Ljuba, Samuel J. Bell, Jonathan Lipton, Eric Eisenstein, Gulmira Kudaiberdieva, Marilyn Wagner, Ioana Mozos, Aleksandra Misak, and Nina Hakacova. “The Research Practicum and International Research Interdisciplinary School (IRIS) initiatives: In memory of Professor Galen S. Wagner M.D., PhD..” J Electrocardiol 50, no. 1 (January 2017): 5–10. https://doi.org/10.1016/j.jelectrocard.2016.11.004.

PMID
27894598
Full Text

Eisenstein, Eric L., Janese M. Willis, Rex Edwards, Kevin J. Anstrom, Kensaku Kawamoto, Guilherme Del Fiol, Fred S. Johnson, and David F. Lobach. “Randomized Trial of Population-Based Clinical Decision Support to Facilitate Care Transitions..” Stud Health Technol Inform 234 (2017): 98–103.

PMID
28186023
Scholars@Duke

Eisenstein, Eric L., Amy Harris Nordo, and Meredith Nahm Zozus. “Using Medical Informatics to Improve Clinical Trial Operations..” Stud Health Technol Inform 234 (2017): 93–97.

PMID
28186022
Scholars@Duke

Ammenwerth, Elske, Nicolet De Keizer, Jytte Brender McNair, Catherine K. Craven, Eric Eisenstein, Andrew Georgiou, Saif Khairat, et al. “How to Teach Health IT Evaluation: Recommendations for Health IT Evaluation Courses..” In Stud Health Technol Inform, 243:3–7, 2017.

PMID
28883158
Scholars@Duke

Østbye, Truls, Marissa Stroo, Eric L. Eisenstein, and John M. Dement. “The Effects of Two Workplace Weight Management Programs and Weight Loss on Health Care Utilization and Costs..” J Occup Environ Med 58, no. 2 (February 2016): 162–69. https://doi.org/10.1097/JOM.0000000000000586.

PMID
26849260
Full Text

Bain, Jesse C., David A. Turner, Kyle J. Rehder, Eric L. Eisenstein, R Duane Davis, Ira M. Cheifetz, and David W. Zaas. “Economic Outcomes of Extracorporeal Membrane Oxygenation With and Without Ambulation as a Bridge to Lung Transplantation..” Respir Care 61, no. 1 (January 2016): 1–7. https://doi.org/10.4187/respcare.03729.

PMID
26264415
Full Text

Andrade, Joao de, Marvin Schwarz, Harold R. Collard, Tedryl Gentry-Bumpass, Thomas Colby, David Lynch, Robert J. Kaner, and Robert J. IPFnet Investigators. “The Idiopathic Pulmonary Fibrosis Clinical Research Network (IPFnet): diagnostic and adjudication processes..” Chest 148, no. 4 (October 2015): 1034–42. https://doi.org/10.1378/chest.14-2889.

PMID
26111071
Full Text

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