Erik Magnus Ohman, MBBS

Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail 7403 Duke North, Durham, NC 27710
Phone (919) 681-2069
Email address ohman001@mc.duke.edu

The main focus of my research is in the management of acute myocardial infarction. My focus has revolved around the use of interventional procedures such as balloon angioplasty, intra-aortic balloon pumping and other support devices for the management of patients with acute myocardial infarction. Through participating and designing a number of randomized trials, we have helped crystallize the management to sustain patency of the infarct-related coronary artery in acute myocardial infarction. Furthermore, I have conducted several large multi-center clinical trials on the use of intra-aortic counterpulsation and angioplasty to better understand the pathophysiology of interventional procedures. Another major focus has been in the area of risk stratification in acute myocardial infarction. Early observations done abroad have led me to use new cardiac markers to identify high and low risk patients. Further research in this area will integrate early and rapid triage along with monitoring of the effect of thrombolysis after reperfusion in patients. A patent in the latter category has already been issued. My continued focus in the performance of multi-center international clinical trials has allowed us to explore different treatment strategies for the management of acute myocardial infarction from an international prospective. We have also collected angioplasty data on nearly 6,000 patients from around North America to further explore international differences in the management of patients using percutaneous interventions.

In Their Words

Education and Training

  • M.B.B.S., Royal College of Surgeons (Ireland), 1981

Publications

Ohman, EM, Christenson, R, Clemmensen, P, and Wagner, GS. "Myocardial salvage after reperfusion. Observations from analysis of serial electrocardiograpic and biochemical indices." Journal of Electrocardiology 25, no. SUPPL. (1992): 10-14.

Full Text

Silverman, AJ, Wetmore, RW, and Ohman, EM. "Intraaortic balloon pump and thrombolysis in AMI [1]." American Heart Journal 123, no. 6 (1992): 1720--.

Scholars@Duke

Davidson, CJ, Sheikh, KH, Kisslo, KB, Phillips, HR, Peter, RH, Behar, VS, Kong, YH, Krucoff, M, Ohman, EM, and Tcheng, JE. "Intracoronary ultrasound evaluation of interventional technologies." Am J Cardiol 68, no. 13 (November 15, 1991): 1305-1309.

PMID
1951117
Scholars@Duke

Hellstrom, HR. "Consequences of reocclusion after successful reperfusion therapy in acute myocardial infarction." Circulation 84, no. 3 (September 1991): 1454-1455. (Letter)

PMID
1884472
Full Text

Christenson, RH, Ohman, EM, Vollmer, RT, Clemmensen, P, Grande, P, and Wagner, GS. "Serum release of the creatine kinase tissue-specific isoforms MM3 and MB2 is simultaneous during myocardial reperfusion." Clin Chim Acta 200, no. 1 (August 15, 1991): 23-33.

PMID
1934508
Scholars@Duke

Califf, RM, Fortin, DF, Frid, DJ, Harlan, WR, Ohman, EM, Bengtson, JR, Nelson, CL, Tcheng, JE, Mark, DB, and Stack, RS. "Restenosis after coronary angioplasty: an overview." Journal of the American College of Cardiology 17, no. 6 Suppl B (May 1991): 2B-13B. (Review)

PMID
2016478
Full Text

Ohman, E, Califf, RM, George, BS, Quigley, PJ, Kereiakes, DJ, Harrelson-Woodlief, L, Candela, RJ, Flanagan, C, Stack, RS, and Topol, EJ. "The use of intraaortic balloon pumping as an adjunct to reperfusion therapy in acute myocardial infarction." American Heart Journal 121, no. 3 (March 1991): 895-901.

Full Text

Ohman, EM, Califf, RM, George, BS, Quigley, PJ, Kereiakes, DJ, Harrelson-Woodlief, L, Candela, RJ, Flanagan, C, Stack, RS, and Topol, EJ. "The use of intraaortic balloon pumping as an adjunct to reperfusion therapy in acute myocardial infarction. The Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) Study Group." American Heart Journal 121, no. 3 Pt 1 (March 1991): 895-901.

PMID
1900381
Full Text

Ohman, EM, Califf, RM, Topol, EJ, Stack, RS, and George, BS. "Intra-aortic balloon pumping: Benefits after thrombolytic therapy." Cardiology Board Review 8, no. 11 (January 1, 1991): 41-56.

Scholars@Duke

Clemmensen, P, Ohman, EM, Sevilla, DC, Peck, S, Wagner, NB, Quigley, PS, Grande, P, Lee, KL, and Wagner, GS. "Changes in standard electrocardiographic ST-segment elevation predictive of successful reperfusion in acute myocardial infarction." Am J Cardiol 66, no. 20 (December 15, 1990): 1407-1411.

PMID
2123601
Scholars@Duke

Pages