Erik Magnus Ohman, MBBS

Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail 7403 Duke North, Durham, NC 27710
Phone (919) 681-2069
Email address ohman001@mc.duke.edu

The main focus of my research is in the management of acute myocardial infarction. My focus has revolved around the use of interventional procedures such as balloon angioplasty, intra-aortic balloon pumping and other support devices for the management of patients with acute myocardial infarction. Through participating and designing a number of randomized trials, we have helped crystallize the management to sustain patency of the infarct-related coronary artery in acute myocardial infarction. Furthermore, I have conducted several large multi-center clinical trials on the use of intra-aortic counterpulsation and angioplasty to better understand the pathophysiology of interventional procedures. Another major focus has been in the area of risk stratification in acute myocardial infarction. Early observations done abroad have led me to use new cardiac markers to identify high and low risk patients. Further research in this area will integrate early and rapid triage along with monitoring of the effect of thrombolysis after reperfusion in patients. A patent in the latter category has already been issued. My continued focus in the performance of multi-center international clinical trials has allowed us to explore different treatment strategies for the management of acute myocardial infarction from an international prospective. We have also collected angioplasty data on nearly 6,000 patients from around North America to further explore international differences in the management of patients using percutaneous interventions.

In Their Words

Education and Training

  • M.B.B.S., Royal College of Surgeons (Ireland), 1981

Publications

Park, D-W, Clare, RM, Schulte, PJ, Pieper, KS, Shaw, LK, Califf, RM, Ohman, EM, Van de Werf, F, Hirji, S, Harrington, RA, Armstrong, PW, Granger, CB, Jeong, M-H, and Patel, MR. "Extent, location, and clinical significance of non-infarct-related coronary artery disease among patients with ST-elevation myocardial infarction." Jama 312, no. 19 (November 2014): 2019-2027.

PMID
25399277
Full Text

Fihn, SD, Blankenship, JC, Alexander, KP, Bittl, JA, Byrne, JG, Fletcher, BJ, Fonarow, GC, Lange, RA, Levine, GN, Maddox, TM, Naidu, SS, Ohman, EM, and Smith, PK. "2014 ACC/AHA/AATS/PCNA/SCAI/STS focused update of the guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines, and the American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons." Journal of the American College of Cardiology 64, no. 18 (November 2014): 1929-1949. (Review)

PMID
25077860
Full Text

Fihn, SD, Blankenship, JC, Alexander, KP, Bittl, JA, Byrne, JG, Fletcher, BJ, Fonarow, GC, Lange, RA, Levine, GN, Maddox, TM, Naidu, SS, Ohman, EM, and Smith, PK. "2014 ACC/AHA/AATS/PCNA/SCAI/STS focused update of the guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines, and the American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons." Circulation 130, no. 19 (November 2014): 1749-1767.

PMID
25070666
Full Text

Magnus Ohman, E. "My approach to evaluation of patients prior to high-risk PCI with left ventricular support devices." Trends in cardiovascular medicine 24, no. 7 (October 2014): 316-317.

PMID
25218672
Full Text

Pershad, A, Fraij, G, Massaro, JM, David, SW, Kleiman, NS, Denktas, AE, Wilson, BH, Dixon, SR, Ohman, EM, Douglas, PS, Moses, JW, and O'Neill, WW. "Comparison of the use of hemodynamic support in patients ≥80 years versus patients <80 years during high-risk percutaneous coronary interventions (from the multicenter protect II randomized study)." American Journal of Cardiology 114, no. 5 (September 1, 2014): 657-664.

Full Text

McDonough, R, and Ohman, EM. "The use of aortic counterpulsation in United States: what can we learn from administrative databases?." American heart journal 168, no. 3 (September 2014): 237-238.

PMID
25173532
Full Text

Ohman, EM, and Alexander, KP. "The challenges with chronic angina." The New England journal of medicine 371, no. 12 (September 2014): 1152-1153.

PMID
25176137
Full Text

Jacobs, AK, Anderson, JL, Halperin, JL, ACC/AHA TASK FORCE MEMBERS, , Anderson, JL, Halperin, JL, Albert, NM, Bozkurt, B, Brindis, RG, Curtis, LH, DeMets, D, Fleisher, LA, Gidding, S, Hochman, JS, Kovacs, RJ, Ohman, EM, Pressler, SJ, Sellke, FW, Shen, W-K, and Wijeysundera, DN. "The evolution and future of ACC/AHA clinical practice guidelines: a 30-year journey: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines." Circulation 130, no. 14 (September 2014): 1208-1217.

PMID
25092464
Full Text

Nishimura, RA, Otto, CM, Bonow, RO, Carabello, BA, Erwin, JP, Guyton, RA, O'Gara, PT, Ruiz, CE, Skubas, NJ, Sorajja, P, Sundt, TM, Thomas, JD, Anderson, JL, Halperin, JL, Albert, NM, Bozkurt, B, Brindis, RG, Creager, MA, Curtis, LH, DeMets, D, Hochman, JS, Kovacs, RJ, Ohman, EM, Pressler, SJ, Sellke, FW, Shen, W-K, Stevenson, WG, Yancy, CW, American College of Cardiology, , American College of Cardiology/American Heart Association, , and American Heart Association, . "2014 AHA/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines." The Journal of Thoracic and Cardiovascular Surgery 148, no. 1 (July 2014): e1-e132. (Review)

PMID
24939033
Full Text

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