Erik Magnus Ohman, MBBS

Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail 7403 Duke North, Durham, NC 27710
Phone (919) 681-2069
Email address ohman001@mc.duke.edu

The main focus of my research is in the management of acute myocardial infarction. My focus has revolved around the use of interventional procedures such as balloon angioplasty, intra-aortic balloon pumping and other support devices for the management of patients with acute myocardial infarction. Through participating and designing a number of randomized trials, we have helped crystallize the management to sustain patency of the infarct-related coronary artery in acute myocardial infarction. Furthermore, I have conducted several large multi-center clinical trials on the use of intra-aortic counterpulsation and angioplasty to better understand the pathophysiology of interventional procedures. Another major focus has been in the area of risk stratification in acute myocardial infarction. Early observations done abroad have led me to use new cardiac markers to identify high and low risk patients. Further research in this area will integrate early and rapid triage along with monitoring of the effect of thrombolysis after reperfusion in patients. A patent in the latter category has already been issued. My continued focus in the performance of multi-center international clinical trials has allowed us to explore different treatment strategies for the management of acute myocardial infarction from an international prospective. We have also collected angioplasty data on nearly 6,000 patients from around North America to further explore international differences in the management of patients using percutaneous interventions.

In Their Words

Education and Training

  • M.B.B.S., Royal College of Surgeons (Ireland), 1981

Publications

Wiviott, SD, White, HD, Ohman, EM, Fox, KAA, Armstrong, PW, Prabhakaran, D, Hafley, G, Lokhnygina, Y, Boden, WE, Hamm, C, Clemmensen, P, Nicolau, JC, Menozzi, A, Ruzyllo, W, Widimsky, P, Oto, A, Leiva-Pons, J, Pavlides, G, Winters, KJ, Roe, MT, and Bhatt, DL. "Prasugrel versus clopidogrel for patients with unstable angina or non-ST-segment elevation myocardial infarction with or without angiography: a secondary, prespecified analysis of the TRILOGY ACS trial." LANCET 382, no. 9892 (August 17, 2013): 605-613.

PMID
23953385
Scholars@Duke

Chan, MY, Sun, J-L, Newby, LK, Lokhnygina, Y, White, HD, Moliterno, DJ, Théroux, P, Ohman, EM, Simoons, ML, Mahaffey, KW, Pieper, KS, Giugliano, RP, Armstrong, PW, Califf, RM, Van de Werf, F, and Harrington, RA. "Trends in clinical trials of non-ST-segment elevation acute coronary syndromes over 15 years." Int J Cardiol 167, no. 2 (July 31, 2013): 548-554. (Review)

PMID
22341697
Full Text

Kern, M, Applegate, R, Bach, RG, Bailey, SR, Bashore, TM, Bass, TA, Bell, M, de Bruyne, B, Garratt, KN, Jeremias, A, Kereiakes, DJ, Klein, LW, Krucoff, MW, Mintz, GS, Morrison, D, Ohman, EM, Pichard, A, Rosenfield, K, Samady, H, Stone, GW, Tommaso, C, Turi, ZG, Uretsky, B, Vetrovec, G, Weiner, BH, Welt, F, and Yeung, AC. "Conversation in cardiology: should FFR and IVUS be counted as PCI?." Catheter Cardiovasc Interv 82, no. 1 (July 1, 2013): 110-115.

PMID
23404738
Full Text

Anderson, JL, Adams, CD, Antman, EM, Bridges, CR, Califf, RM, Casey, DE, Chavey, WE, Fesmire, FM, Hochman, JS, Levin, TN, Lincoff, AM, Peterson, ED, Theroux, P, Wenger, NK, Wright, RS, Jneid, H, Ettinger, SM, Ganiats, TG, Philippides, GJ, Jacobs, AK, Halperin, JL, Albert, NM, Creager, MA, DeMets, D, Guyton, RA, Kushner, FG, Ohman, EM, Stevenson, W, and Yancy, CW. "2012 ACCF/AHA focused update incorporated into the ACCF/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines." J Am Coll Cardiol 61, no. 23 (June 11, 2013): e179-e347. (Review)

PMID
23639841
Full Text

Bahit, MC, Lopes, RD, Clare, RM, Newby, LK, Pieper, KS, Van de Werf, F, Armstrong, PW, Mahaffey, KW, Harrington, RA, Diaz, R, Ohman, EM, White, HD, James, S, and Granger, CB. "Heart failure complicating non-ST-segment elevation acute coronary syndrome: timing, predictors, and clinical outcomes." JACC. Heart failure 1, no. 3 (June 3, 2013): 223-229.

PMID
24621874
Full Text

Barakat, RR, Berchuck, A, Markman, M, and Randall, ME. "Preface." Principles and Practice of Gynecologic Oncology: Sixth Edition (May 8, 2013): xi-xii.

Scholars@Duke

Anderson, JL, Halperin, JL, Albert, NM, Bozkurt, B, Brindis, RG, Curtis, LH, DeMets, D, Guyton, RA, Hochman, JS, Kovacs, RJ, Ohman, EM, Pressler, SJ, Sellke, FW, Shen, W-K, Wann, LS, Curtis, AB, Ellenbogen, KA, Estes, NAM, Ezekowitz, MD, Jackman, WM, January, CT, Lowe, JE, Page, RL, Slotwiner, DJ, Stevenson, WG, Tracy, CM, Fuster, V, Rydén, LE, Cannom, DS, Crijns, HJ, Curtis, AB, Ellenbogen, KA, Le Heuzey, J-Y, Kay, GN, Olsson, SB, Prystowsky, EN, Tamargo, JL, and Wann, S. "Management of patients with atrial fibrillation (compilation of 2006 ACCF/AHA/ESC and 2011 ACCF/AHA/HRS recommendations): a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines." J Am Coll Cardiol 61, no. 18 (May 7, 2013): 1935-1944. (Review)

PMID
23558044
Full Text

Roe, MT, Li, S, Thomas, L, Wang, TY, Alexander, KP, Ohman, EM, and Peterson, ED. "Long-term outcomes after invasive management for older patients with non-ST-segment elevation myocardial infarction." Circ Cardiovasc Qual Outcomes 6, no. 3 (May 1, 2013): 323-332.

PMID
23652734
Full Text

Rose, JJ, Newby, LK, Broderick, S, Chiswell, K, Van de Werf, F, Armstrong, PW, Mahaffey, KW, Harrington, RA, Ohman, EM, Giugliano, RP, Goodman, SG, White, HD, Califf, RM, Granger, CB, and Lopes, RD. "Left bundle branch block in non-ST-segment elevation acute coronary syndromes. Incidence, angiographic characteristics, and clinical outcomes." Journal of the American College of Cardiology 61, no. 13 (April 2013): 1461-1463. (Letter)

PMID
23500249
Full Text

Kumbhani, DJ, Steg, PG, Cannon, CP, Eagle, KA, Jr, SSC, Crowley, K, Goto, S, Ohman, EM, Bakris, GL, Perlstein, TS, Kinlay, S, Bhatt, DL, and Investigators, REACHR. "Resistant hypertension: a frequent and ominous finding among hypertensive patients with atherothrombosis." EUROPEAN HEART JOURNAL 34, no. 16 (April 2013): 1204-1214.

PMID
23144048
Full Text

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