Feng Gao, MD

Professor of Medicine
Member of the Duke Human Vaccine Institute
Campus mail 244 Sands Bldg, Box 102359, Durham, NC 27710
Phone (919) 668-6433
Email address feng.gao@duke.edu

Dr. Feng Gao is Professor of Medicine at Duke University. The Gao laboratory has a long-standing interest in elucidating the origins and evolution of human and simian inmmunodeficiency viruses (HIV and SIV), and in studying HIV/SIV gene function and pathogenic mechanisms from the evolutionary perspective. These studies have led to new strategies to better understand HIV origins,  biology, pathogenesis and drug resistance, and to design new AIDS vaccines.

Education and Training

  • M.D., Harbin Medical University (China), 1984

Publications

Rademeyer, Cecilia, Bette Korber, Michael S. Seaman, Elena E. Giorgi, Ruwayhida Thebus, Alexander Robles, Daniel J. Sheward, et al. “Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization..” Plos Pathog 12, no. 7 (July 2016). https://doi.org/10.1371/journal.ppat.1005742.

PMID
27434311
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Zhang, Ruijun, Laurent Verkoczy, Kevin Wiehe, S. Munir Alam, Nathan I. Nicely, Sampa Santra, Todd Bradley, et al. “Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages..” Sci Transl Med 8, no. 336 (April 27, 2016). https://doi.org/10.1126/scitranslmed.aaf0618.

PMID
27122615
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Bonsignori, Mattia, Tongqing Zhou, Zizhang Sheng, Lei Chen, Feng Gao, M Gordon Joyce, Gabriel Ozorowski, et al. “Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody..” Cell 165, no. 2 (April 7, 2016): 449–63. https://doi.org/10.1016/j.cell.2016.02.022.

PMID
26949186
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Zhang, Guoqing, Fangping Cai, Ivette Lorenzana de Rivera, Zhiyong Zhou, Jing Zhang, John Nkengasong, Feng Gao, and Chunfu Yang. “Simultaneous Detection of Major Drug Resistance Mutations of HIV-1 Subtype B Viruses from Dried Blood Spot Specimens by Multiplex Allele-Specific Assay..” J Clin Microbiol 54, no. 1 (January 2016): 220–22. https://doi.org/10.1128/JCM.02833-15.

PMID
26560533
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Hora, Bhavna, Sheila M. Keating, Yue Chen, Ana M. Sanchez, Ester Sabino, Gillian Hunt, Johanna Ledwaba, et al. “Genetic Characterization of a Panel of Diverse HIV-1 Isolates at Seven International Sites..” Plos One 11, no. 6 (2016). https://doi.org/10.1371/journal.pone.0157340.

PMID
27314585
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Chen, Yue, Bhavna Hora, Todd DeMarco, Sharaf Ali Shah, Manzoor Ahmed, Ana M. Sanchez, Chang Su, et al. “Fast Dissemination of New HIV-1 CRF02/A1 Recombinants in Pakistan..” Plos One 11, no. 12 (2016). https://doi.org/10.1371/journal.pone.0167839.

PMID
27973597
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Jiang, Liping, Rongjun Fan, Shiyang Sun, Peihu Fan, Weiheng Su, Yan Zhou, Feng Gao, Fei Xu, Wei Kong, and Chunlai Jiang. “A new EV71 VP3 epitope in norovirus P particle vector displays neutralizing activity and protection in vivo in mice..” Vaccine 33, no. 48 (November 27, 2015): 6596–6603. https://doi.org/10.1016/j.vaccine.2015.10.104.

PMID
26529072
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Hraber, Peter, Bette Korber, Kshitij Wagh, Elena E. Giorgi, Tanmoy Bhattacharya, S. Gnanakaran, Alan S. Lapedes, et al. “Longitudinal Antigenic Sequences and Sites from Intra-Host Evolution (LASSIE) Identifies Immune-Selected HIV Variants..” Viruses 7, no. 10 (October 21, 2015): 5443–75. https://doi.org/10.3390/v7102881.

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26506369
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Moody, M Anthony, Feng Gao, Thaddeus C. Gurley, Joshua D. Amos, Amit Kumar, Bhavna Hora, Dawn J. Marshall, et al. “Strain-Specific V3 and CD4 Binding Site Autologous HIV-1 Neutralizing Antibodies Select Neutralization-Resistant Viruses..” Cell Host Microbe 18, no. 3 (September 9, 2015): 354–62. https://doi.org/10.1016/j.chom.2015.08.006.

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26355218
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Blasi, Maria, J Harris Carpenter, Bala Balakumaran, Andrea Cara, Feng Gao, and Mary E. Klotman. “Identification of HIV-1 genitourinary tract compartmentalization by analyzing the env gene sequences in urine..” Aids 29, no. 13 (August 24, 2015): 1651–57. https://doi.org/10.1097/QAD.0000000000000757.

PMID
26372275
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Pages