Gwynn Douglas Long, MD

Professor of Medicine
Campus mail Box 3961 Med Ctr, Durham, NC 27710
Phone (919) 668-1000
Email address gwynn.long@duke.edu

1. High dose therapy and autologous and allogeneic stem cell rescue for hematologic malignancies (especially multiple myeloma) and solid tumors.
2. Non-myeloablative allogeneic transplants for hematologic malignancies and solid tumors.
3. Supportive care for hematopoietic stem cell transplants.
4. Prevention and therapy of graft versus host disease.

Education and Training

  • Fellow in Medical Oncology, Medicine, Stanford University, 1987 - 1990
  • Medical Resident, Medicine, Vanderbilt University, 1983 - 1986
  • M.D., Wake Forest University, 1983
  • M.S., Wake Forest University, 1979

Publications

Horwitz, M. E., G. Long, P. Holman, E. Libby, G. C. Calandra, and J. R. Schriber. “Efficacy and safety of hematopoietic stem cell remobilization with plerixafor+G-CSF in adult patients with germ cell tumors..” Bone Marrow Transplant 47, no. 10 (October 2012): 1283–86. https://doi.org/10.1038/bmt.2012.21.

PMID
22343676
Full Text

Horwitz, M. E., J. P. Chute, C. Gasparetto, G. D. Long, C. McDonald, A. Morris, D. A. Rizzieri, K. M. Sullivan, and N. J. Chao. “Preemptive dosing of plerixafor given to poor stem cell mobilizers on day 5 of G-CSF administration..” Bone Marrow Transplant 47, no. 8 (August 2012): 1051–55. https://doi.org/10.1038/bmt.2011.217.

PMID
22080963
Full Text

Chen, D. -. F., V. K. Prasad, G. Broadwater, N. L. Reinsmoen, A. DeOliveira, A. Clark, K. M. Sullivan, et al. “Differential impact of inhibitory and activating Killer Ig-Like Receptors (KIR) on high-risk patients with myeloid and lymphoid malignancies undergoing reduced intensity transplantation from haploidentical related donors..” Bone Marrow Transplant 47, no. 6 (June 2012): 817–23. https://doi.org/10.1038/bmt.2011.181.

PMID
22139069
Full Text

Kanda, J., M. E. Horwitz, G. D. Long, C. Gasparetto, K. M. Sullivan, J. P. Chute, A. Morris, et al. “Outcomes of a 1-day nonmyeloablative salvage regimen for patients with primary graft failure after allogeneic hematopoietic cell transplantation..” Bone Marrow Transplant 47, no. 5 (May 2012): 700–705. https://doi.org/10.1038/bmt.2011.158.

PMID
21804612
Full Text

Kanda, Junya, David A. Rizzieri, Cristina Gasparetto, Gwynn D. Long, John P. Chute, Keith M. Sullivan, Ashley Morris, et al. “Adult dual umbilical cord blood transplantation using myeloablative total body irradiation (1350 cGy) and fludarabine conditioning..” Biol Blood Marrow Transplant 17, no. 6 (June 2011): 867–74. https://doi.org/10.1016/j.bbmt.2010.09.009.

PMID
20868761
Full Text

Craciunescu, Oana I., Beverly A. Steffey, Chris R. Kelsey, Nicole A. Larrier, Cathy J. Paarz-Largay, Robert G. Prosnitz, Nelson Chao, et al. “Renal shielding and dosimetry for patients with severe systemic sclerosis receiving immunoablation with total body irradiation in the scleroderma: cyclophosphamide or transplantation trial..” Int J Radiat Oncol Biol Phys 79, no. 4 (March 15, 2011): 1248–55. https://doi.org/10.1016/j.ijrobp.2010.05.036.

PMID
20800376
Full Text

Rizzieri, David A., Christopher Crout, Robert Storms, Jared Golob, Gwynn D. Long, Cristina Gasparetto, Keith M. Sullivan, et al. “Feasibility of low-dose interleukin-2 therapy following T-cell-depleted nonmyeloablative allogeneic hematopoietic stem cell transplantation from HLA-matched or -mismatched family member donors..” Cancer Invest 29, no. 1 (January 2011): 56–61. https://doi.org/10.3109/07357907.2010.535055.

PMID
21166499
Full Text

Rizzieri, David A., Robert Storms, Dong-Feng Chen, Gwynn Long, Yiping Yang, Daniel A. Nikcevich, Cristina Gasparetto, et al. “Natural killer cell-enriched donor lymphocyte infusions from A 3-6/6 HLA matched family member following nonmyeloablative allogeneic stem cell transplantation..” Biol Blood Marrow Transplant 16, no. 8 (August 2010): 1107–14. https://doi.org/10.1016/j.bbmt.2010.02.018.

PMID
20188202
Full Text

Crout, Christopher A., Liang-Piu Koh, Jon P. Gockerman, Joseph O. Moore, Carlos Decastro, Gwynn D. Long, Louis Diehl, et al. “Overcoming drug resistance in mantle cell lymphoma using a combination of dose-dense and intense therapy..” Cancer Invest 28, no. 6 (July 2010): 654–60. https://doi.org/10.3109/07357901003631015.

PMID
20521909
Full Text

Gasparetto, Cristina, Jon P. Gockerman, Louis F. Diehl, Carlos M. de Castro, Joseph O. Moore, Gwynn D. Long, Mitchell E. Horwitz, et al. “"Short course" bortezomib plus melphalan and prednisone as induction prior to transplant or as frontline therapy for nontransplant candidates in patients with previously untreated multiple myeloma..” Biol Blood Marrow Transplant 16, no. 1 (January 2010): 70–77. https://doi.org/10.1016/j.bbmt.2009.08.017.

PMID
19733251
Full Text

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