Hans-Ewald Hohmeier, MD, PhD

Associate Professor in Medicine
Member of Sarah W. Stedman Nutrition and Metabolism Center
Affiliate of the Regeneration Next Initiative
Campus mail 300 N Duke Street, Durham, NC 27701
Phone (919) 479-2342
Email address hans.hohmeier@duke.edu

Education and Training

  • Postdoctoral Fellow, Biochemistry, UT Southwestern Medical School, 1995 - 1997
  • Postdoctoral Fellow, Immunology, UT Southwestern Medical School, 1991 - 1995
  • Ph.D., Georg August Universitat Gottingen (Germany), 1992
  • M.D., University of Hannover (Germany), 1986

Publications

Yang, Shumin, Ulrika Fransson, Lillian Fagerhus, Lena Stenson Holst, Hans E. Hohmeier, Erik Renström, and Hindrik Mulder. “Enhanced cAMP protein kinase A signaling determines improved insulin secretion in a clonal insulin-producing beta-cell line (INS-1 832/13)..” Mol Endocrinol 18, no. 9 (September 2004): 2312–20. https://doi.org/10.1210/me.2004-0148.

PMID
15166255
Full Text

Newgard, Christopher B., Hans E. Hohmeier, Danhong Lu, Mette Valentin Jensen, Veronique V. Tran, Guoxun Chen, Shawn Burgess, and A Dean Sherry. “Understanding of basic mechanisms of beta-cell function and survival: prelude to new diabetes therapies..” Cell Biochem Biophys 40, no. 3 Suppl (2004): 159–68.

PMID
15289651
Scholars@Duke

Hohmeier, H. E., V. V. Tran, G. Chen, R. Gasa, and C. B. Newgard. “Inflammatory mechanisms in diabetes: lessons from the beta-cell..” Int J Obes Relat Metab Disord 27 Suppl 3 (December 2003): S12–16. https://doi.org/10.1038/sj.ijo.0802493.

PMID
14704737
Full Text

Tran, Veronique Vien, Guoxun Chen, Christopher B. Newgard, and Hans E. Hohmeier. “Discrete and complementary mechanisms of protection of beta-cells against cytokine-induced and oxidative damage achieved by bcl-2 overexpression and a cytokine selection strategy..” Diabetes 52, no. 6 (June 2003): 1423–32. https://doi.org/10.2337/diabetes.52.6.1423.

PMID
12765953
Full Text

Chen, G., H. E. Hohmeier, and C. B. Newgard. “Expression of the transcription factor STAT-1 alpha in insulinoma cells protects against cytotoxic effects of multiple cytokines..” J Biol Chem 276, no. 1 (January 5, 2001): 766–72. https://doi.org/10.1074/jbc.M008330200.

PMID
11024034
Full Text

Chen, G., H. E. Hohmeier, R. Gasa, V. V. Tran, and C. B. Newgard. “Selection of insulinoma cell lines with resistance to interleukin-1beta- and gamma-interferon-induced cytotoxicity..” Diabetes 49, no. 4 (April 2000): 562–70. https://doi.org/10.2337/diabetes.49.4.562.

PMID
10871193
Full Text

Hohmeier, H. E., H. Mulder, G. Chen, R. Henkel-Rieger, M. Prentki, and C. B. Newgard. “Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion..” Diabetes 49, no. 3 (March 2000): 424–30. https://doi.org/10.2337/diabetes.49.3.424.

PMID
10868964
Full Text

Hohmeier, H. E., A. Thigpen, V. V. Tran, R. Davis, and C. B. Newgard. “Stable expression of manganese superoxide dismutase (MnSOD) in insulinoma cells prevents IL-1beta- induced cytotoxicity and reduces nitric oxide production..” J Clin Invest 101, no. 9 (May 1, 1998): 1811–20. https://doi.org/10.1172/JCI1489.

PMID
9576743
Full Text

Pages