Hans-Ewald Hohmeier, MD, PhD

Associate Professor in Medicine
Member of Sarah W. Stedman Nutrition and Metabolism Center
Affiliate of the Regeneration Next Initiative
Campus mail 300 N Duke Street, Durham, NC 27701
Phone (919) 479-2342
Email address hans.hohmeier@duke.edu

Education and Training

  • Postdoctoral Fellow, Biochemistry, UT Southwestern Medical School, 1995 - 1997
  • Postdoctoral Fellow, Immunology, UT Southwestern Medical School, 1991 - 1995
  • Ph.D., Georg August Universitat Gottingen (Germany), 1992
  • M.D., University of Hannover (Germany), 1986

Publications

Hohmeier, HE, and Newgard, CB. "Islets for all?." Nat Biotechnol 23, no. 10 (October 2005): 1231-1232.

PMID
16211061
Full Text

Hohmeier, HE, and Newgard, CB. "Cell lines derived from pancreatic islets." Mol Cell Endocrinol 228, no. 1-2 (December 30, 2004): 121-128. (Review)

PMID
15541576
Full Text

Yang, S, Fransson, U, Fagerhus, L, Holst, LS, Hohmeier, HE, Renström, E, and Mulder, H. "Enhanced cAMP protein kinase A signaling determines improved insulin secretion in a clonal insulin-producing β-cell line (INS-1 832/13)." Molecular Endocrinology 18, no. 9 (2004): 2312-2320.

PMID
15166255
Full Text

Newgard, CB, Hohmeier, HE, Lu, D, Jensen, MV, Tran, VV, Chen, G, Burgess, S, and Sherry, AD. "Understanding of basic mechanisms of beta-cell function and survival: prelude to new diabetes therapies." Cell Biochem Biophys 40, no. 3 Suppl (2004): 159-168. (Review)

PMID
15289651
Scholars@Duke

Hohmeier, HE, Tran, VV, Chen, G, Gasa, R, and Newgard, CB. "Inflammatory mechanisms in diabetes: lessons from the beta-cell." Int J Obes Relat Metab Disord 27 Suppl 3 (December 2003): S12-S16. (Review)

PMID
14704737
Full Text

Tran, VV, Chen, G, Newgard, CB, and Hohmeier, HE. "Discrete and complementary mechanisms of protection of beta-cells against cytokine-induced and oxidative damage achieved by bcl-2 overexpression and a cytokine selection strategy." Diabetes 52, no. 6 (June 2003): 1423-1432.

PMID
12765953
Scholars@Duke

Chen, G, Hohmeier, HE, and Newgard, CB. "Expression of the transcription factor STAT-1 alpha in insulinoma cells protects against cytotoxic effects of multiple cytokines." J Biol Chem 276, no. 1 (January 5, 2001): 766-772.

PMID
11024034
Full Text

Chen, G, Hohmeier, HE, Gasa, R, Tran, VV, and Newgard, CB. "Selection of insulinoma cell lines with resistance to interleukin-1beta- and gamma-interferon-induced cytotoxicity." Diabetes 49, no. 4 (April 2000): 562-570.

PMID
10871193
Scholars@Duke

Hohmeier, HE, Mulder, H, Chen, G, Henkel-Rieger, R, Prentki, M, and Newgard, CB. "Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion." Diabetes 49, no. 3 (March 2000): 424-430.

PMID
10868964
Scholars@Duke

Hohmeier, HE, Thigpen, A, Tran, VV, Davis, R, and Newgard, CB. "Stable expression of manganese superoxide dismutase (MnSOD) in insulinoma cells prevents IL-1beta- induced cytotoxicity and reduces nitric oxide production." J Clin Invest 101, no. 9 (May 1, 1998): 1811-1820.

PMID
9576743
Full Text

Pages