Harvey Jay Cohen, MD

Professor of Medicine
Walter Kempner Professor of Medicine, in the School of Medicine
Director, Center for the Study of Aging & Human Development
Faculty Research Scholar of DuPRI's Center for Population Health & Aging
Member of the Duke Cancer Institute
Campus mail 3502 Blue Zone Duke Clinic, Center For Aging, Trent Drive, Durham, NC 27710
Phone (919) 660-7502
Email address harvey.cohen@duke.edu

Dr. Cohen's research program includes clinical research relating to aspects of the pathways to functional decline with aging, geriatric assessment, and cancer in the elderly.

Pathways to functional decline are being explored through the NIA funded Claude Pepper Older Americans Independence Center, and includes studies of the contributions of age related physiologic change, in particular changes in inflammatory parameters, comorbid diseases and conditions, environment, genetics, and the interactionas among them. Data are derived from several current studies as well as previously collected data sets from the Established Populations for Epidemiologic Studies of the Elderly (EPESE), National Long Term Care Survey, and the Chinese Longevity Study (with Dr. Zeng Yi). Previous work has demonstrated the important contributions of age related inflammation and coagulation activation to functional status.

Geriatric assessment approaches have been studied in a number of randomized and controlled studies and work is now concentrating on the application of Comprehensive Geriatric Assessment tools to the evaluation and treatment of elderly patients with cancer. This is an extension and continuation of a long standing interest in geriatric oncology. Previous studies have elucidated age-related patterns of disease presentation, treatment approaches, clinical trials, survivorship, quality of life, impact of comrobidities and functional outcomes. Dr. Cohen is co-chair of the Cancer in the Elderly Committee of Cancer and Acute Luekemia Group B (CALGB). A number of active studies and ongoing data bases aree being utilized to address these questions.

Education and Training

  • M.D., State University of New York at Brooklyn, 1965

Publications

Rao, KM, Currie, MS, Ruff, JC, and Cohen, HJ. "Lack of correlation between induction of chemotactic peptide receptors and stimulus-induced actin polymerization in HL-60 cells treated with dibutyryl cyclic adenosine monophosphate or retinoic acid." Cancer Res 48, no. 23 (December 1, 1988): 6721-6726.

PMID
2846157
Scholars@Duke

Rao, KM, Crawford, J, Currie, MS, and Cohen, HJ. "Actin depolymerization and inhibition of capping induced by pentoxifylline in human lymphocytes and neutrophils." J Cell Physiol 137, no. 3 (December 1988): 577-582.

PMID
2848043
Full Text

Rivich, DA, Rosen, GM, and Cohen, HJ. "Membrane protein organization of peripheral blood lymphocytes from healthy young and aged adults." Mech Ageing Dev 45, no. 1 (October 1988): 65-74.

PMID
2851077
Scholars@Duke

Koenig, HG, Meador, KG, Cohen, HJ, and Blazer, DG. "Depression in elderly hospitalized patients with medical illness." Archives of Internal Medicine 148, no. 9 (September 1988): 1929-1936.

PMID
3415405
Full Text

Schwartz, CL, and Cohen, HJ. "Preleukemic syndromes and other syndromes predisposing to leukemia." Pediatric clinics of North America 35, no. 4 (August 1988): 853-871. (Review)

PMID
3047657
Scholars@Duke

Koenig, HG, Meador, KG, Cohen, HJ, and Blazer, DG. "Self-rated depression scales and screening for major depression in the older hospitalized patient with medical illness." J Am Geriatr Soc 36, no. 8 (August 1988): 699-706.

PMID
3042842
Scholars@Duke

Whitin, JC, and Cohen, HJ. "Disorders of respiratory burst termination." Hematology/oncology clinics of North America 2, no. 2 (June 1988): 289-299. (Review)

PMID
2839461
Scholars@Duke

Saltz, CC, McVey, LJ, Becker, PM, Feussner, JR, and Cohen, HJ. "Impact of a geriatric consultation team on discharge placement and repeat hospitalization." Gerontologist 28, no. 3 (June 1988): 344-350.

PMID
3294117
Scholars@Duke

Rao, KM, Misukonis, MA, Cohen, HJ, and Weinberg, JB. "Cooperative effect of tumor necrosis factor and gamma-interferon on chemotactic peptide receptor expression and stimulus-induced actin polymerization in HL-60 cells." Blood 71, no. 4 (April 1988): 1062-1067.

PMID
3128345
Scholars@Duke

Cohen, HJ. "Monoclonal gammopathies and aging." Hosp Pract (Off Ed) 23, no. 3A (March 30, 1988): 75-80.

PMID
3127410
Scholars@Duke

Pages