Harvey Jay Cohen, MD

Professor of Medicine
Walter Kempner Professor of Medicine, in the School of Medicine
Director, Center for the Study of Aging & Human Development
Faculty Research Scholar of DuPRI's Center for Population Health & Aging
Member of the Duke Cancer Institute
Campus mail 3502 Blue Zone Duke Clinic, Center for Aging, Trent Drive, Durham, NC 27710
Phone (919) 660-7502
Email address harvey.cohen@duke.edu

Dr. Cohen's research program includes clinical research relating to aspects of the pathways to functional decline with aging, geriatric assessment, and cancer in the elderly.

Pathways to functional decline are being explored through the NIA funded Claude Pepper Older Americans Independence Center, and includes studies of the contributions of age related physiologic change, in particular changes in inflammatory parameters, comorbid diseases and conditions, environment, genetics, and the interactionas among them. Data are derived from several current studies as well as previously collected data sets from the Established Populations for Epidemiologic Studies of the Elderly (EPESE), National Long Term Care Survey, and the Chinese Longevity Study (with Dr. Zeng Yi). Previous work has demonstrated the important contributions of age related inflammation and coagulation activation to functional status.

Geriatric assessment approaches have been studied in a number of randomized and controlled studies and work is now concentrating on the application of Comprehensive Geriatric Assessment tools to the evaluation and treatment of elderly patients with cancer. This is an extension and continuation of a long standing interest in geriatric oncology. Previous studies have elucidated age-related patterns of disease presentation, treatment approaches, clinical trials, survivorship, quality of life, impact of comrobidities and functional outcomes. Dr. Cohen is co-chair of the Cancer in the Elderly Committee of Cancer and Acute Luekemia Group B (CALGB). A number of active studies and ongoing data bases aree being utilized to address these questions.

Education and Training

  • M.D., State University of New York at Brooklyn, 1965

Publications

Hauch, T. W., J. D. Shelbourne, H. J. Cohen, D. Mason, and W. B. Kremer. “Meningeal mycosis fungoides: clinical and cellular characteristics..” Ann Intern Med 82, no. 4 (April 1975): 499–505.

PMID
1168035
Scholars@Duke

Paris, S., W. B. Kremer, and H. J. Cohen. “Familial lymhoid malignancy: impaired immunologic responses in uninvolved family members.” Clin.Res. 23, no. 3 (January 1, 1975).

Scholars@Duke

Cohen, H. J., and L. G. Lefer. “Intranuclear inclusions in Bence Jones lambda plasma cell myeloma..” Blood 45, no. 1 (January 1975): 131–39.

PMID
803105
Scholars@Duke

Cohen, H. J., and R. W. Rundles. “Managing the complications of plasma cell myeloma..” Arch Intern Med 135, no. 1 (January 1975): 177–84.

PMID
122891
Scholars@Duke

Cohen, H. J. “Human lymphocyte surface immunoglobulin capping. Normal characteristics and anomalous behavior of chronic lymphocytic leukemic lymphocytes..” J Clin Invest 55, no. 1 (January 1975): 84–93. https://doi.org/10.1172/JCI107921.

PMID
1088910
Full Text

Cohen, H. J., J. L. Johnson, and K. V. Rajagopalan. “Molecular basis of the biological function of molybdenum. Developmental patterns of sulfite oxidase and xanthine oxidase in the rat..” Arch Biochem Biophys 164, no. 2 (October 1974): 440–46.

PMID
4376662
Scholars@Duke

Johnson, J. L., W. R. Waud, H. J. Cohen, and K. V. Rajagopalan. “Molecular basis of the biological function of molybdenum. Molybdenum-free xanthine oxidase from livers of tungsten-treated rats..” J Biol Chem 249, no. 16 (August 25, 1974): 5056–61.

PMID
4368927
Scholars@Duke

Johnson, J. L., H. J. Cohen, and K. V. Rajagopalan. “Molecular basis of the biological function of molybdenum. Molybdenum-free sulfite oxidase from livers of tungsten-treated rats..” J Biol Chem 249, no. 16 (August 25, 1974): 5046–55.

PMID
4368926
Scholars@Duke

Minkin, W., S. B. Frank, S. R. Wolman, and H. J. Cohen. “Lymphedema in Noonan's syndrome..” Int J Dermatol 13, no. 3 (July 1974): 179–83.

PMID
4429607
Scholars@Duke

Pages