Harvey Jay Cohen, MD

Professor of Medicine
Walter Kempner Professor of Medicine, in the School of Medicine
Director, Center for the Study of Aging & Human Development
Faculty Research Scholar of DuPRI's Center for Population Health & Aging
Member of the Duke Cancer Institute
Campus mail 3502 Blue Zone Duke Clinic, Center For Aging, Trent Drive, Durham, NC 27710
Phone (919) 660-7502
Email address harvey.cohen@duke.edu

Dr. Cohen's research program includes clinical research relating to aspects of the pathways to functional decline with aging, geriatric assessment, and cancer in the elderly.

Pathways to functional decline are being explored through the NIA funded Claude Pepper Older Americans Independence Center, and includes studies of the contributions of age related physiologic change, in particular changes in inflammatory parameters, comorbid diseases and conditions, environment, genetics, and the interactionas among them. Data are derived from several current studies as well as previously collected data sets from the Established Populations for Epidemiologic Studies of the Elderly (EPESE), National Long Term Care Survey, and the Chinese Longevity Study (with Dr. Zeng Yi). Previous work has demonstrated the important contributions of age related inflammation and coagulation activation to functional status.

Geriatric assessment approaches have been studied in a number of randomized and controlled studies and work is now concentrating on the application of Comprehensive Geriatric Assessment tools to the evaluation and treatment of elderly patients with cancer. This is an extension and continuation of a long standing interest in geriatric oncology. Previous studies have elucidated age-related patterns of disease presentation, treatment approaches, clinical trials, survivorship, quality of life, impact of comrobidities and functional outcomes. Dr. Cohen is co-chair of the Cancer in the Elderly Committee of Cancer and Acute Luekemia Group B (CALGB). A number of active studies and ongoing data bases aree being utilized to address these questions.

Education and Training

  • M.D., State University of New York at Brooklyn, 1965

Publications

Cohen, HJ. "An Accidental Career in Geriatrics." Journal of the American Geriatrics Society 63, no. 9 (September 2015): 1945-1948.

PMID
26277439
Full Text

Berger, M, Nadler, JW, Browndyke, J, Terrando, N, Ponnusamy, V, Cohen, HJ, Whitson, HE, and Mathew, JP. "Postoperative Cognitive Dysfunction: Minding the Gaps in Our Knowledge of a Common Postoperative Complication in the Elderly." Anesthesiology Clinics 33, no. 3 (September 2015): 517-550. (Review)

PMID
26315636
Full Text

Belsky, DW, Caspi, A, Houts, R, Cohen, HJ, Corcoran, DL, Danese, A, Harrington, H, Israel, S, Levine, ME, Schaefer, JD, Sugden, K, Williams, B, Yashin, AI, Poulton, R, and Moffitt, TE. "Quantification of biological aging in young adults." Proceedings of the National Academy of Sciences of the United States of America 112, no. 30 (July 6, 2015): E4104-E4110.

PMID
26150497
Full Text

Gajra, A, McCall, L, Muss, HB, Cohen, HJ, Jatoi, A, Ballman, KV, Partridge, AH, Sutton, L, Parker, BA, Magrinat, G, Lafky, JM, and Hurria, A. "Abstract P5-15-07: Association of patient preference for adjuvant chemotherapy (chemo) at baseline (BL) with toxicity, mental health, function, quality of life (QoL) and survival in older women with early stage breast cancer (ESBC) [CALGB 49907 Alliance]." May 1, 2015.

Full Text

Koenig, HG, Pearce, MJ, Nelson, B, Shaw, SF, Robins, CJ, Daher, NS, Cohen, HJ, Berk, LS, Bellinger, DL, Pargament, KI, Rosmarin, DH, Vasegh, S, Kristeller, J, Juthani, N, Nies, D, and King, MB. "Religious vs. conventional cognitive behavioral therapy for major depression in persons with chronic medical illness: a pilot randomized trial." The Journal of Nervous and Mental Disease 203, no. 4 (April 2015): 243-251.

PMID
25816046
Full Text

Pearce, MJ, Koenig, HG, Robins, CJ, Nelson, B, Shaw, SF, Cohen, HJ, and King, MB. "Religiously integrated cognitive behavioral therapy: a new method of treatment for major depression in patients with chronic medical illness." Psychotherapy (Chicago, Ill.) 52, no. 1 (March 2015): 56-66.

PMID
25365155
Full Text

Lamont, EB, Schilsky, RL, He, Y, Muss, H, Cohen, HJ, Hurria, A, Meilleur, A, Kindler, HL, Venook, A, Lilenbaum, R, Niell, H, Goldberg, RM, Joffe, S, and Alliance for Clinical Trials in Oncology, . "Generalizability of trial results to elderly Medicare patients with advanced solid tumors (Alliance 70802)." Journal of the National Cancer Institute 107, no. 1 (January 2015): 336-null.

PMID
25432408
Full Text

Pearce, MJ, Koenig, HG, Robins, CJ, Daher, N, Shaw, SF, Nelson, B, Berk, LS, Bellinger, D, Cohen, HJ, and King, MB. "Effects of religious versus conventional cognitive-behavioral therapy on generosity in major depression and chronic medical illness: A randomized clinical trial." Spirituality in Clinical Practice 2, no. 3 (2015): 202-215.

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Price, E, Artz, AS, Barnhart, H, Sapp, S, Chelune, G, Ershler, WB, Walston, JD, Gordeuk, VR, Berger, NA, Reuben, D, Prchal, J, Rao, SV, Roy, CN, Supiano, MA, Schrier, SL, and Cohen, HJ. "A prospective randomized wait list control trial of intravenous iron sucrose in older adults with unexplained anemia and serum ferritin 20-200ng/mL." Blood Cells, Molecules, and Diseases 53, no. 4 (December 1, 2014): 221-230.

Full Text

Faul, LA, Luta, G, Luta, G, Sheppard, V, Isaacs, C, Cohen, HJ, Muss, HB, Yung, R, Clapp, JD, Winer, E, Hudis, C, Tallarico, M, Wang, J, Barry, WT, and Mandelblatt, JS. "Associations among survivorship care plans, experiences of survivorship care, and functioning in older breast cancer survivors: CALGB/Alliance 369901." Journal of cancer survivorship : research and practice 8, no. 4 (December 2014): 627-637.

PMID
24917307
Full Text

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