Harvey Jay Cohen, MD

Professor of Medicine
Walter Kempner Professor of Medicine, in the School of Medicine
Director, Center for the Study of Aging & Human Development
Faculty Research Scholar of DuPRI's Center for Population Health & Aging
Member of the Duke Cancer Institute
Campus mail 3502 Blue Zone Duke Clinic, Center for Aging, Trent Drive, Durham, NC 27710
Phone (919) 660-7502
Email address harvey.cohen@duke.edu

Dr. Cohen's research program includes clinical research relating to aspects of the pathways to functional decline with aging, geriatric assessment, and cancer in the elderly.

Pathways to functional decline are being explored through the NIA funded Claude Pepper Older Americans Independence Center, and includes studies of the contributions of age related physiologic change, in particular changes in inflammatory parameters, comorbid diseases and conditions, environment, genetics, and the interactionas among them. Data are derived from several current studies as well as previously collected data sets from the Established Populations for Epidemiologic Studies of the Elderly (EPESE), National Long Term Care Survey, and the Chinese Longevity Study (with Dr. Zeng Yi). Previous work has demonstrated the important contributions of age related inflammation and coagulation activation to functional status.

Geriatric assessment approaches have been studied in a number of randomized and controlled studies and work is now concentrating on the application of Comprehensive Geriatric Assessment tools to the evaluation and treatment of elderly patients with cancer. This is an extension and continuation of a long standing interest in geriatric oncology. Previous studies have elucidated age-related patterns of disease presentation, treatment approaches, clinical trials, survivorship, quality of life, impact of comrobidities and functional outcomes. Dr. Cohen is co-chair of the Cancer in the Elderly Committee of Cancer and Acute Luekemia Group B (CALGB). A number of active studies and ongoing data bases aree being utilized to address these questions.

Education and Training

  • M.D., State University of New York at Brooklyn, 1965

Publications

Hurria, A, Naylor, M, and Cohen, HJ. "Improving the Quality of Cancer Care in an Aging Population Recommendations From an IOM Report." JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 310, no. 17 (November 6, 2013): 1795-1796.

PMID
24193075
Full Text

Povsic, TJ, Sloane, R, Green, JB, Zhou, J, Pieper, CF, Pearson, MP, Peterson, ED, Cohen, HJ, and Morey, MC. "Depletion of circulating progenitor cells precedes overt diabetes: A substudy from the VA enhanced fitness trial." Journal of Diabetes and its Complications 27, no. 6 (November 1, 2013): 633-636.

Full Text

Povsic, TJ, Sloane, R, Green, JB, Zhou, J, Pieper, CF, Pearson, MP, Peterson, ED, Cohen, HJ, and Morey, MC. "Depletion of circulating progenitor cells precedes overt diabetes: a substudy from the VA enhanced fitness trial." J Diabetes Complications 27, no. 6 (November 2013): 633-636.

PMID
24055327
Full Text

Wildiers, H, Mauer, M, Pallis, A, Hurria, A, Mohile, SG, Luciani, A, Curigliano, G, Extermann, M, Lichtman, SM, Ballman, K, Cohen, HJ, Muss, H, and Wedding, U. "End points and trial design in geriatric oncology research: a joint European organisation for research and treatment of cancer--Alliance for Clinical Trials in Oncology--International Society Of Geriatric Oncology position article." J Clin Oncol 31, no. 29 (October 10, 2013): 3711-3718.

PMID
24019549
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Whitson, HE, Whitaker, D, Potter, G, McConnell, E, Tripp, F, Sanders, LL, Muir, KW, Cohen, HJ, and Cousins, SW. "A low-vision rehabilitation program for patients with mild cognitive deficits." JAMA Ophthalmol 131, no. 7 (July 2013): 912-919.

PMID
23619914
Full Text

Kuchibhatla, MN, Fillenbaum, GG, Kraus, WE, Cohen, HJ, and Blazer, DG. "Trajectory classes of body mass index in a representative elderly community sample." J Gerontol A Biol Sci Med Sci 68, no. 6 (June 2013): 699-704.

PMID
23089335
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Freedman, RA, Pitcher, B, Keating, NL, Ballman, KV, Mandelblatt, J, Kornblith, AB, Kimmick, GG, Hurria, A, Winer, EP, Hudis, CA, Cohen, HJ, Muss, HB, and Alliance for Clinical Trials in Oncology, . "Cognitive function in older women with breast cancer treated with standard chemotherapy and capecitabine on Cancer and Leukemia Group B 49907." Breast Cancer Res Treat 139, no. 2 (June 2013): 607-616.

PMID
23681403
Full Text

Unroe, KT, and Cohen, HJ. "Multidisciplinary Models of Care." (January 2, 2013): 487-497. (Chapter)

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Freedman, RA, Pitcher, B, Keating, NL, Ballman, KV, Mandelblatt, J, Kornblith, AB, Kimmick, GG, Hurria, A, Winer, EP, Hudis, CA, Cohen, HJ, and Muss, HB. "Cognitive function in older women with breast cancer treated with standard chemotherapy and capecitabine on Cancer and Leukemia Group B 49907." Breast Cancer Research and Treatment 139, no. 2 (2013): 607-616.

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Mandelblatt, JS, Makgoeng, SB, Luta, G, Hurria, A, Kimmick, G, Isaacs, C, Tallarico, M, Barry, WT, Pitcher, B, Winer, EP, and al, E. "A planned, prospective comparison of short-term quality of life outcomes among older breast cancer patients treated with standard chemotherapy in a randomized clinical trial vs. an observational study: CALGB #49907 and #369901." Journal of Geriatric Oncology (2013).

PMID
24472479
Full Text

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