Harvey Jay Cohen, MD

Professor of Medicine
Walter Kempner Professor of Medicine, in the School of Medicine
Director, Center for the Study of Aging & Human Development
Faculty Research Scholar of DuPRI's Center for Population Health & Aging
Member of the Duke Cancer Institute
Campus mail 3502 Blue Zone Duke Clinic, Center For Aging, Trent Drive, Durham, NC 27710
Phone (919) 660-7502
Email address harvey.cohen@duke.edu

Dr. Cohen's research program includes clinical research relating to aspects of the pathways to functional decline with aging, geriatric assessment, and cancer in the elderly.

Pathways to functional decline are being explored through the NIA funded Claude Pepper Older Americans Independence Center, and includes studies of the contributions of age related physiologic change, in particular changes in inflammatory parameters, comorbid diseases and conditions, environment, genetics, and the interactionas among them. Data are derived from several current studies as well as previously collected data sets from the Established Populations for Epidemiologic Studies of the Elderly (EPESE), National Long Term Care Survey, and the Chinese Longevity Study (with Dr. Zeng Yi). Previous work has demonstrated the important contributions of age related inflammation and coagulation activation to functional status.

Geriatric assessment approaches have been studied in a number of randomized and controlled studies and work is now concentrating on the application of Comprehensive Geriatric Assessment tools to the evaluation and treatment of elderly patients with cancer. This is an extension and continuation of a long standing interest in geriatric oncology. Previous studies have elucidated age-related patterns of disease presentation, treatment approaches, clinical trials, survivorship, quality of life, impact of comrobidities and functional outcomes. Dr. Cohen is co-chair of the Cancer in the Elderly Committee of Cancer and Acute Luekemia Group B (CALGB). A number of active studies and ongoing data bases aree being utilized to address these questions.

Education and Training

  • M.D., State University of New York at Brooklyn, 1965

Publications

Tuchman, SA, Shapiro, GR, Ershler, WB, Badros, A, Cohen, HJ, Dispenzieri, A, Flores, IQ, Kanapuru, B, Jurivich, D, Longo, DL, Nourbakhsh, A, Palumbo, A, Walston, J, and Yates, JW. "Multiple myeloma in the very old: an IASIA conference report." Journal of the National Cancer Institute 106, no. 5 (April 3, 2014).

PMID
24700806
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Kanesvaran, R, Wang, W, Yang, Y, Wei, Z, Jia, L, Li, F, Wu, S, Bai, C, Xie, H, Zhang, H, Yang, G, Sloane, R, Li, P, and Cohen, HJ. "Characteristics and treatment options of elderly Chinese patients with cancer as determined by Comprehensive Geriatric Assessment (CGA)." Journal of geriatric oncology 5, no. 2 (April 2014): 171-178.

PMID
24486112
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Ballman, KV, Mauer, M, Wedding, U, Mohile, SG, Muss, H, Extermann, M, Luciani, A, Cohen, HJ, Hurria, A, Lichtman, SM, Curigliano, G, and Wildiers, H. "Reply to L.K. Mell et al." Journal of clinical oncology : official journal of the American Society of Clinical Oncology 32, no. 10 (April 2014): 1090-1091. (Letter)

PMID
24550420
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Cohen, HJ, Naylor, M, and Hurria, A. "Underrepresentation of older adults in cancer trials--reply." JAMA 311, no. 9 (March 2014): 966-967. (Letter)

PMID
24595790
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George, LK, Palmore, E, and Cohen, HJ. "The Duke Center for the Study of Aging: one of our earliest roots." Gerontologist 54, no. 1 (February 2014): 59-66.

PMID
23733867
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Hurria, A, Wildes, T, Blair, SL, Browner, IS, Cohen, HJ, De Shazo, M, Dotan, E, Edil, BH, Extermann, M, Ganti, AKP, Holmes, HM, Jagsi, R, Karlekar, MB, Keating, NL, Korc-Grodzicki, B, McKoy, JM, Medeiros, BC, Mrozek, E, O'Connor, T, Rugo, HS, Rupper, RW, Silliman, RA, Stirewalt, DL, Tew, WP, Walter, LC, Weir, AB, Bergman, MA, and Sundar, H. "Senior adult oncology, version 2.2014: Clinical practice guidelines in oncology." JNCCN Journal of the National Comprehensive Cancer Network 12, no. 1 (January 1, 2014): 82-126.

Scholars@Duke

Blair, CK, Morey, MC, Desmond, RA, Cohen, HJ, Sloane, R, Snyder, DC, and Demark-Wahnefried, W. "Light-intensity activity attenuates functional decline in older cancer survivors." Medicine and Science in Sports and Exercise 46, no. 7 (January 1, 2014): 1375-1383.

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Koenig, HG, Berk, LS, Daher, NS, Pearce, MJ, Bellinger, DL, Robins, CJ, Nelson, B, Shaw, SF, Cohen, HJ, and King, MB. "Religious involvement is associated with greater purpose, optimism, generosity and gratitude in persons with major depression and chronic medical illness." Journal of Psychosomatic Research 77, no. 2 (January 1, 2014): 135-143.

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Fu, C, Tan, Z, Liu, R, Hao, S, Li, Z, Chen, P, Jang, T, Merchant, M, Whitin, JC, Wang, O, Guo, M, Cohen, HJ, Recht, L, and Ling, XB. "CSF protein dynamic driver network: At the crossroads of brain tumorigenesis." January 1, 2014.

Full Text

Hurria, A, Wildes, T, Blair, SL, Browner, IS, Cohen, HJ, Deshazo, M, Dotan, E, Edil, BH, Extermann, M, Ganti, AKP, Holmes, HM, Jagsi, R, Karlekar, MB, Keating, NL, Korc-Grodzicki, B, McKoy, JM, Medeiros, BC, Mrozek, E, O'Connor, T, Rugo, HS, Rupper, RW, Silliman, RA, Stirewalt, DL, Tew, WP, Walter, LC, Weir, AB, Bergman, MA, and Sundar, H. "Senior adult oncology, version 2.2014: clinical practice guidelines in oncology ." Journal of the National Comprehensive Cancer Network : JNCCN 12, no. 1 (January 2014): 82-126.

PMID
24453295
Full Text

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