Ian James Welsby, MBBS

Professor of Anesthesiology
Professor of Medicine
Campus mail 2301 Erwin Road, 5691H Hafs Building, Durham, NC 27710
Phone (919) 681-6752
Email address ian.welsby@duke.edu

As a practicing cardiothoracic anesthesiologist, I have contributed to the better understanding of the management and of perioperative thrombosis (particularly HIT). This has been as a Duke site PI for the Rare Thrombotic Diseases Consortium led by Dr T.L Ortel and a clinical collaborator with the basic and translational science approach to HIT led by Dr G Arepally. I have also championed novel approaches to dealing with perioperative HIT such as plasmaperesis.

Similarly, I have been a local leader in establishing management of transfusion approaches to major cardiac surgery including the novel introduction of autologous plateletpheresis to limit exposure to allogeneic platelet transfusions in this highly transfused population, identifying the transfusion requirements during thoracic aortic reconstruction and promoting use of a lower dose of rFVIIa use in this population, changing established clinical practice.

My research interests focus on perioperative transfusion and hematology concerns. Recently, Dr Kor (Mayo Clinic) and I received a multiple PI R-01 award to evaluate point-of-care/bedside washing of packed red blood cells to reduce perioperative lung injury. This novel repurposing of commonly available “cell-saver” technology is, for most surgical cases, the only practical means of delivering a washed product, and promises to be a critical advancement in perioperative transfusion medicine. I also have a longstanding interest in the rejuvenation of RBCs to normalize oxygen delivery capacity of transfused RBCs. Such a development will be of tremendous importance to transfusion practice, particularly for highly transfused populations. 

In summary, I have dedicated my research career to improving the outcome of patients undergoing cardiothoracic surgery, understanding perioperative coagulopathy, and optimizing transfusion practice. 

Education and Training

  • Anaesthetic Registrar, Anaesthetics, Royal London Hospital (United Kingdom), 1995 - 1995
  • Anaesthetic registrar, Anaesthetic, Royal London Hospital (United Kingdom), 1994 - 1995
  • Temporary Registrar, Anaesthetics, Royal London Hospital (United Kingdom), 1993 - 1994
  • Senior House Officer, Anesthetics, Royal London Hospital (United Kingdom), 1992 - 1993
  • Senior House Officer, Intensive Care, Royal London Hospital (United Kingdom), 1992 - 1992
  • Senior House Officer, Accident And Emergency, Royal London Hospital (United Kingdom), 1991 - 1992
  • House Officer, General And Vascular Surgery, Royal London Hospital (United Kingdom), 1991 - 1991
  • House Officer, Chest And General Medicine, Royal London Hospital (United Kingdom), 1990 - 1991
  • Anaesthetic Registrar, Anaesthetics, Royal London Hospital (United Kingdom), 1990 - 1990
  • M.B.B.S., University College London (United Kingdom), 1990