James Abbruzzese, MD

Professor of Medicine
D. C. I. Professor of Medical Oncology
Chief, Division of Medical Oncology
Member of the Duke Cancer Institute
Campus mail 440 Mudd Building, Box 3406, Durham, NC 27710
Email address james.abbruzzese@duke.edu

My research interests include the clinical study and treatment of pancreatic cancer.

In Their Words

Education and Training

  • Resident, Internal Medicine, Johns Hopkins University School of Medicine, 1979 - 1981
  • Intern, Internal Medicine, Johns Hopkins University School of Medicine, 1978 - 1979
  • M.D., University of Chicago, 1978

Publications

Kaseb, AO, Xiao, L, Hassan, MM, Chae, YK, Lee, J-S, Vauthey, J-N, Krishnan, S, Cheung, S, Hassabo, HM, Aloia, T, Conrad, C, Curley, SA, Vierling, JM, Jalal, P, Raghav, K, Wallace, M, Rashid, A, Abbruzzese, JL, Wolff, RA, and Morris, JS. "Development and validation of insulin-like growth factor-1 score to assess hepatic reserve in hepatocellular carcinoma." JNCI Journal of the National Cancer Institute 106, no. 5 (May 9, 2014).

PMID
24815863
Full Text

Guo, R, Overman, M, Chatterjee, D, Rashid, A, Shroff, S, Wang, H, Katz, MH, Fleming, JB, Varadhachary, GR, Abbruzzese, JL, and Wang, H. "Aberrant expression of p53, p21, cyclin D1, and Bcl2 and their clinicopathological correlation in ampullary adenocarcinoma." Human pathology 45, no. 5 (May 2014): 1015-1023.

PMID
24746206
Full Text

Koay, EJ, Truty, MJ, Cristini, V, Thomas, RM, Chen, R, Chatterjee, D, Kang, Y, Bhosale, PR, Tamm, EP, Crane, CH, Javle, M, Katz, MH, Gottumukkala, VN, Rozner, MA, Shen, H, Lee, JE, Wang, H, Chen, Y, Plunkett, W, Abbruzzese, JL, Wolff, RA, Varadhachary, GR, Ferrari, M, and Fleming, JB. "Transport properties of pancreatic cancer describe gemcitabine delivery and response." The Journal of Clinical Investigation 124, no. 4 (April 2014): 1525-1536.

PMID
24614108
Full Text

Shroff, S, Rashid, A, Wang, H, Katz, MH, Abbruzzese, JL, Fleming, JB, and Wang, H. "SOX9: a useful marker for pancreatic ductal lineage of pancreatic neoplasms." Human pathology 45, no. 3 (March 2014): 456-463.

PMID
24418153
Full Text

Shroff, RT, and Abbruzzese, JL. "Molecular Pathogenesis of Pancreatic Adenocarcinoma." In The Molecular Basis of Cancer: Fourth Edition. March 1, 2014.

Full Text

Estrella, JS, Li, L, Rashid, A, Wang, H, Katz, MH, Fleming, JB, Abbruzzese, JL, and Wang, H. "Solid pseudopapillary neoplasm of the pancreas: clinicopathologic and survival analyses of 64 cases from a single institution." The American Journal of Surgical Pathology 38, no. 2 (February 2014): 147-157.

PMID
24418850
Full Text

Wang, H, Chen, Y, Lin, P, Li, L, Zhou, G, Liu, G, Logsdon, C, Jin, J, Abbruzzese, JL, Tan, T-H, and Wang, H. "The CUL7/F-box and WD repeat domain containing 8 (CUL7/Fbxw8) ubiquitin ligase promotes degradation of hematopoietic progenitor kinase 1." The Journal of biological chemistry 289, no. 7 (February 2014): 4009-4017.

PMID
24362026
Full Text

Estrella, J, Li, L, Rashid, A, Wang, H, Katz, MH, Fleming, JB, Abbruzzese, JL, and Wang, H. "Solid Pseudopapillary Neoplasm of the Pancreas: Clinicopathologic and Survival Analyses of 64 Cases from a Single Institution." February 2014.

Scholars@Duke

Kaseb, AO, Shah, NN, Hassabo, HM, Morris, JS, Xiao, L, Abaza, YM, Soliman, K, Lee, J-S, Vauthey, J-N, Wallace, M, Aloia, TA, Curley, S, Abbruzzese, JL, and Hassan, MM. "Reassessing hepatocellular carcinoma staging in a changing patient population." Oncology 86, no. 2 (January 8, 2014): 63-71.

PMID
24401634
Full Text

Kaseb, AO, Xiao, L, Hassan, MM, Chae, YK, Lee, JS, Vauthey, JN, Krishnan, S, Cheung, S, Hassabo, HM, Aloia, T, Conrad, C, Curley, SA, Vierling, JM, Jalal, P, Raghav, K, Wallace, M, Rashid, A, Abbruzzese, JL, Wolff, RA, and Morris, JS. "Development and validation of insulin-like growth factor-1 score to assess hepatic reserve in hepatocellular carcinoma." Journal of the National Cancer Institute 106, no. 5 (January 1, 2014).

Scholars@Duke

Pages