James Abbruzzese, MD

Professor of Medicine
D. C. I. Distinguished Professor of Medical Oncology
Chief, Division of Medical Oncology
Member of the Duke Cancer Institute
Campus mail 440 Mudd Building, Box 3406, Durham, NC 27710
Email address james.abbruzzese@duke.edu

My research interests include the clinical study and treatment of pancreatic cancer.

In Their Words

Education and Training

  • Resident, Internal Medicine, Johns Hopkins University School of Medicine, 1979 - 1981
  • Intern, Internal Medicine, Johns Hopkins University School of Medicine, 1978 - 1979
  • M.D., The University of Chicago, 1978

Publications

Capello, Michela, Leonidas E. Bantis, Ghislaine Scelo, Yang Zhao, Peng Li, Dilsher S. Dhillon, Nikul J. Patel, et al. “Sequential Validation of Blood-Based Protein Biomarker Candidates for Early-Stage Pancreatic Cancer.” J Natl Cancer Inst 109, no. 4 (April 1, 2017). https://doi.org/10.1093/jnci/djw266.

PMID
28376157
Full Text

Capello, Michela, Leonidas E. Bantis, Ghislaine Scelo, Yang Zhao, Peng Li, Dilsher S. Dhillon, Nikul J. Patel, et al. “Sequential Validation of Blood-Based Protein Biomarker Candidates for Early-Stage Pancreatic Cancer.” J Natl Cancer Inst 109, no. 4 (April 2017). https://doi.org/10.1093/jnci/djw266.

PMID
27986802
Full Text

Cloyd, Jordan M., Matthew H. G. Katz, Laura Prakash, Gauri R. Varadhachary, Robert A. Wolff, Rachna T. Shroff, Milind Javle, et al. “Preoperative Therapy and Pancreatoduodenectomy for Pancreatic Ductal Adenocarcinoma: a 25-Year Single-Institution Experience.” J Gastrointest Surg 21, no. 1 (January 2017): 164–74. https://doi.org/10.1007/s11605-016-3265-1.

PMID
27778257
Full Text

Ye, Min, Weiqin Lu, Xiaojie Wang, Cong Wang, James L. Abbruzzese, Guang Liang, Xiaokun Li, and Yongde Luo. “FGF21-FGFR1 Coordinates Phospholipid Homeostasis, Lipid Droplet Function, and ER Stress in Obesity.” Endocrinology 157, no. 12 (December 2016): 4754–69. https://doi.org/10.1210/en.2016-1710.

PMID
27690692
Full Text

Palta, M., B. Czito, J. Abbruzzese, H. Uronis, E. A. Duffy, D. T. Blazer, and C. G. Willett. “Interim Acute Toxicity Analysis and Surgical Outcomes of Neoadjuvant Gemcitabine/nab-Paclitaxel and Hypofractionated Image Guided Intensity Modulated Radiation Therapy in Resectable and Borderline Resectable Pancreatic Cancer (ANCHOR) Study.” Int J Radiat Oncol Biol Phys 96, no. 2S (October 1, 2016): S204–5. https://doi.org/10.1016/j.ijrobp.2016.06.509.

PMID
27675789
Full Text

Palta, M., B. Czito, J. Abbruzzese, H. Uronis, E. A. Duffy, D. T. Blazer, and C. G. Willett. “Interim Acute Toxicity Analysis and Surgical Outcomes of Neoadjuvant Gemcitabine/nab-Paclitaxel and Hypofractionated Image Guided Intensity Modulated Radiation Therapy in Resectable and Borderline Resectable Pancreatic Cancer (ANCHOR) Study.” In International Journal of Radiation Oncology Biology Physics, 96:S204–5, 2016.

Scholars@Duke

Zhang, Tian, Rengasamy Boominathan, Brad Foulk, Chandra Rao, Gabor Kemeny, John H. Strickler, James L. Abbruzzese, et al. “Development of a Novel c-MET-Based CTC Detection Platform.” Mol Cancer Res 14, no. 6 (June 2016): 539–47. https://doi.org/10.1158/1541-7786.MCR-16-0011.

PMID
26951228
Full Text

Overman, M. J., V. Morris, B. Kee, D. Fogelman, L. Xiao, C. Eng, A. Dasari, et al. “Utility of a molecular prescreening program in advanced colorectal cancer for enrollment on biomarker-selected clinical trials.” Ann Oncol 27, no. 6 (June 2016): 1068–74. https://doi.org/10.1093/annonc/mdw073.

PMID
27045102
Full Text

Parsons, Henrique A., Vickie E. Baracos, David S. Hong, James Abbruzzese, Eduardo Bruera, and Razelle Kurzrock. “The effects of curcumin (diferuloylmethane) on body composition of patients with advanced pancreatic cancer.” Oncotarget 7, no. 15 (April 12, 2016): 20293–304. https://doi.org/10.18632/oncotarget.7773.

PMID
26934122
Full Text

Li, Donghui, Jennifer Moughan, Christopher Crane, John P. Hoffman, William F. Regine, Ross A. Abrams, Howard Safran, et al. “RECQ1 A159C Polymorphism Is Associated With Overall Survival of Patients With Resected Pancreatic Cancer: A Replication Study in NRG Oncology Radiation Therapy Oncology Group 9704.” Int J Radiat Oncol Biol Phys 94, no. 3 (March 1, 2016): 554–60. https://doi.org/10.1016/j.ijrobp.2015.10.062.

PMID
26725729
Full Text

Pages