James Abbruzzese, MD

Professor of Medicine
D. C. I. Professor of Medical Oncology
Chief, Division of Medical Oncology
Member of the Duke Cancer Institute
Campus mail 440 Mudd Building, Box 3406, Durham, NC 27710
Email address james.abbruzzese@duke.edu

My research interests include the clinical study and treatment of pancreatic cancer.

In Their Words

Education and Training

  • Resident, Internal Medicine, Johns Hopkins University School of Medicine, 1979 - 1981
  • Intern, Internal Medicine, Johns Hopkins University School of Medicine, 1978 - 1979
  • M.D., University of Chicago, 1978

Publications

Lenzi, R., M. N. Raber, D. Gravel, P. Frost, and J. L. Abbruzzese. “Phase I and II trials of a laboratory-derived synergistic combination of cisplatin and 2'-deoxy-5-azacytidine.” International Journal of Oncology 6, no. 2 (January 1, 1995): 447–50.

Scholars@Duke

Evans, D. B., J. L. Abbruzzese, J. E. Lee, S. D. Leach, C. Charnsangavej, K. R. Cleary, D. J. Buchholz, and T. A. Rich. “Preoperative chemoradiation for adenocarcinoma of the pancreas: M.D. Anderson experience.” Seminars in Surgical Oncology 11, no. 2 (January 1, 1995): 132–40. https://doi.org/10.1002/ssu.2980110210.

Full Text

Abbruzzese, J. L. “Novel diagnostic and therapeutic approaches to pancreatic cancer.” Cancer Bulletin 46, no. 6 (December 1, 1994): 525–31.

Scholars@Duke

Leach, S. D., T. A. Rich, J. L. Abbruzzese, J. E. Lee, K. R. Cleary, R. L. Katz, C. Charnsangavej, et al. “Preoperative chemoradiotherapy, pancreaticoduodenectomy, and external- beam intraoperative radiotherapy for pancreatic adenocarcinoma: The M.D. Anderson experience.” Cancer Bulletin 46, no. 6 (December 1, 1994): 518–24.

Scholars@Duke

Pazdur, R., Y. Lassere, V. Rhodes, J. A. Ajani, S. M. Sugarman, Y. Z. Patt, D. V. Jones, A. B. Markowitz, J. L. Abbruzzese, and B. Bready. “Phase II trial of uracil and tegafur plus oral leucovorin: an effective oral regimen in the treatment of metastatic colorectal carcinoma..” J Clin Oncol 12, no. 11 (November 1994): 2296–2300. https://doi.org/10.1200/JCO.1994.12.11.2296.

PMID
7964943
Full Text

Abbruzzese, J. L., M. C. Abbruzzese, K. R. Hess, M. N. Raber, R. Lenzi, and P. Frost. “Unknown primary carcinoma: natural history and prognostic factors in 657 consecutive patients..” J Clin Oncol 12, no. 6 (June 1994): 1272–80. https://doi.org/10.1200/JCO.1994.12.6.1272.

PMID
8201389
Full Text

Pazdur, R., Y. Lassere, L. T. Soh, J. A. Ajani, B. Bready, E. Soo, S. Sugarman, Y. Patt, J. L. Abbruzzese, and B. Levin. “Phase II trial of docetaxel (Taxotere) in metastatic colorectal carcinoma..” Ann Oncol 5, no. 5 (May 1994): 468–70. https://doi.org/10.1093/oxfordjournals.annonc.a058883.

PMID
7915537
Full Text

Hubbard, K. P., J. O. Roehm, and J. L. Abbruzzese. “The Bird's Nest Filter. An alternative to long-term oral anticoagulation in patients with advanced malignancies..” Am J Clin Oncol 17, no. 2 (April 1994): 115–17.

PMID
8141103
Scholars@Duke

Moore, D. F., R. Pazdur, J. L. Abbruzzese, J. A. Ajani, D. W. Dubovsky, J. L. Wade, R. J. Belt, C. Mangold, B. Bready, and R. J. Winn. “Phase II trial of edatrexate in patients with advanced pancreatic adenocarcinoma..” Ann Oncol 5, no. 3 (March 1994): 286–87. https://doi.org/10.1093/oxfordjournals.annonc.a058810.

PMID
8186177
Full Text

Fuhrman, G. M., C. Charnsangavej, J. L. Abbruzzese, K. R. Cleary, R. G. Martin, C. J. Fenoglio, and D. B. Evans. “Thin-section contrast-enhanced computed tomography accurately predicts the resectability of malignant pancreatic neoplasms..” Am J Surg 167, no. 1 (January 1994): 104–11. https://doi.org/10.1016/0002-9610(94)90060-4.

PMID
7906097
Full Text

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