James Abbruzzese, MD

Professor of Medicine
D. C. I. Distinguished Professor of Medical Oncology
Chief, Division of Medical Oncology
Member of the Duke Cancer Institute
Campus mail 440 Mudd Building, Box 3406, Durham, NC 27710
Email address james.abbruzzese@duke.edu

My research interests include the clinical study and treatment of pancreatic cancer.

In Their Words

Education and Training

  • Resident, Internal Medicine, Johns Hopkins University School of Medicine, 1979 - 1981
  • Intern, Internal Medicine, Johns Hopkins University School of Medicine, 1978 - 1979
  • M.D., The University of Chicago, 1978

Publications

Li, D., Y. Mao, P. Chang, C. Liu, M. M. Hassan, S. J. Yeung, and J. L. Abbruzzese. “Impacts of new-onset and long-term diabetes on clinical outcome of pancreatic cancer.” American Journal of Cancer Research 5, no. 10 (January 1, 2015): 3260–69.

Scholars@Duke

Koay, Eugene J., Flavio E. Baio, Alexander Ondari, Mark J. Truty, Vittorio Cristini, Ryan M. Thomas, Rong Chen, et al. “Intra-tumoral heterogeneity of gemcitabine delivery and mass transport in human pancreatic cancer.” Phys Biol 11, no. 6 (November 26, 2014): 065002. https://doi.org/10.1088/1478-3975/11/6/065002.

PMID
25427073
Full Text

Wang, H., J. S. Estrella, D. Chatterjee, M. H. Katz, A. Rashid, R. A. Wolff, G. R. Varadhachary, et al. “Hepatobiliary/Pancreas Pathology: SY11-3 PANCREATIC DUCTAL ADENOCARCINOMA: NEOADJUVANT THERAPIES AND PATHOLOGY.” Pathology 46 Suppl 2 (October 2014): S25. https://doi.org/10.1097/01.PAT.0000454135.19954.47.

PMID
25188109
Full Text

Kaseb, Ahmed O., Lianchun Xiao, Manal M. Hassan, Young Kwang Chae, Ju-Seog Lee, Jean-Nicolas Vauthey, Sunil Krishnan, et al. “Development and validation of insulin-like growth factor-1 score to assess hepatic reserve in hepatocellular carcinoma.” J Natl Cancer Inst 106, no. 5 (May 9, 2014). https://doi.org/10.1093/jnci/dju088.

PMID
24815863
Full Text

Guo, Rongjun, Michael Overman, Deyali Chatterjee, Asif Rashid, Stuti Shroff, Hua Wang, Matthew H. Katz, et al. “Aberrant expression of p53, p21, cyclin D1, and Bcl2 and their clinicopathological correlation in ampullary adenocarcinoma.” Hum Pathol 45, no. 5 (May 2014): 1015–23. https://doi.org/10.1016/j.humpath.2013.12.016.

PMID
24746206
Full Text

Koay, Eugene J., Mark J. Truty, Vittorio Cristini, Ryan M. Thomas, Rong Chen, Deyali Chatterjee, Ya’an Kang, et al. “Transport properties of pancreatic cancer describe gemcitabine delivery and response.” J Clin Invest 124, no. 4 (April 2014): 1525–36. https://doi.org/10.1172/JCI73455.

PMID
24614108
Full Text

Shroff, Stuti, Asif Rashid, Hua Wang, Matthew H. Katz, James L. Abbruzzese, Jason B. Fleming, and Huamin Wang. “SOX9: a useful marker for pancreatic ductal lineage of pancreatic neoplasms.” Hum Pathol 45, no. 3 (March 2014): 456–63. https://doi.org/10.1016/j.humpath.2013.10.008.

PMID
24418153
Full Text

Wang, Hua, Yue Chen, Ping Lin, Lei Li, Guisheng Zhou, Guangchao Liu, Craig Logsdon, et al. “The CUL7/F-box and WD repeat domain containing 8 (CUL7/Fbxw8) ubiquitin ligase promotes degradation of hematopoietic progenitor kinase 1.” J Biol Chem 289, no. 7 (February 14, 2014): 4009–17. https://doi.org/10.1074/jbc.M113.520106.

PMID
24362026
Full Text

Pages