Medical Oncology

James Abbruzzese, MD

Professor of Medicine
D. C. I. Professor of Medical Oncology
Chief, Division of Medical Oncology
Member of the Duke Cancer Institute
Campus mail 440 Mudd Building, Box 3406, Durham, NC 27710
Email address james.abbruzzese@duke.edu

My research interests include the clinical study and treatment of pancreatic cancer.

In Their Words

Education and Training

  • Resident, Internal Medicine, Johns Hopkins University School of Medicine, 1979 - 1981
  • Intern, Internal Medicine, Johns Hopkins University School of Medicine, 1978 - 1979
  • M.D., University of Chicago, 1978

Grants

Publications

Tzeng, Ching-Wei D., Matthew H. G. Katz, Jason B. Fleming, Jeffrey E. Lee, Peter W. T. Pisters, Holly M. Holmes, Gauri R. Varadhachary, et al. “Morbidity and mortality after pancreaticoduodenectomy in patients with borderline resectable type C clinical classification..” J Gastrointest Surg 18, no. 1 (January 2014): 146–55. https://doi.org/10.1007/s11605-013-2371-6.

PMID
24129825
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Kaseb, Ahmed O., Neeraj N. Shah, Hesham M. Hassabo, Jeffrey S. Morris, Lianchun Xiao, Yasmin M. Abaza, Khalid Soliman, et al. “Reassessing hepatocellular carcinoma staging in a changing patient population..” Oncology 86, no. 2 (2014): 63–71. https://doi.org/10.1159/000356573.

PMID
24401634
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Zenali, Maryam, Michael J. Overman, Asif Rashid, Russell B. Broaddus, Hua Wang, Matthew H. Katz, Jason B. Fleming, James L. Abbruzzese, and Huamin Wang. “Clinicopathologic features and prognosis of duodenal adenocarcinoma and comparison with ampullary and pancreatic ductal adenocarcinoma..” Hum Pathol 44, no. 12 (December 2013): 2792–98. https://doi.org/10.1016/j.humpath.2013.07.030.

PMID
24139211
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Chatterjee, Deyali, Matthew H. Katz, Asif Rashid, Jeannelyn S. Estrella, Hua Wang, Gauri R. Varadhachary, Robert A. Wolff, et al. “Pancreatic intraepithelial neoplasia and histological changes in non-neoplastic pancreas associated with neoadjuvant therapy in patients with pancreatic ductal adenocarcinoma..” Histopathology 63, no. 6 (December 2013): 841–51. https://doi.org/10.1111/his.12234.

PMID
24111684
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Abbott, Daniel E., Ching-Wei David Tzeng, Ryan P. Merkow, Scott B. Cantor, George J. Chang, Matthew Harold Katz, David J. Bentrem, et al. “The cost-effectiveness of neoadjuvant chemoradiation is superior to a surgery-first approach in the treatment of pancreatic head adenocarcinoma..” Ann Surg Oncol 20 Suppl 3 (December 2013): S500–508. https://doi.org/10.1245/s10434-013-2882-0.

PMID
23397153
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Luo, Yongde, Chaofeng Yang, Min Ye, Chengliu Jin, James L. Abbruzzese, Mong-Hong Lee, Sai-Ching J. Yeung, and Wallace L. McKeehan. “Deficiency of metabolic regulator FGFR4 delays breast cancer progression through systemic and microenvironmental metabolic alterations..” Cancer Metab 1, no. 1 (November 25, 2013). https://doi.org/10.1186/2049-3002-1-21.

PMID
24279986
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Stuti, S., S. Shroff, M. J. Overman, A. Rashid, R. T. Shroff, H. Wang, D. Chatterjee, et al. “The expression of pten is associated with improved prognosis in patients with ampullary adenocarcinoma after pancreaticoduodenectomy.” Archives of Pathology and Laboratory Medicine 137, no. 11 (November 1, 2013): 1619–26. https://doi.org/10.5858/arpa.2012-0418-OA).

Full Text

Shroff, Stuti, Michael J. Overman, Asif Rashid, Rachna T. Shroff, Hua Wang, Deyali Chatterjee, Matthew H. Katz, et al. “The expression of PTEN is associated with improved prognosis in patients with ampullary adenocarcinoma after pancreaticoduodenectomy..” Arch Pathol Lab Med 137, no. 11 (November 2013): 1619–26. https://doi.org/10.5858/arpa.2012-0418-OA.

PMID
24168499
Full Text

Hassan, Manal M., Ahmed Kaseb, Carol J. Etzel, Hashem El-Serag, Margaret R. Spitz, Ping Chang, Katherine S. Hale, et al. “Genetic variation in the PNPLA3 gene and hepatocellular carcinoma in USA: risk and prognosis prediction..” Mol Carcinog 52 Suppl 1 (November 2013): E139–47. https://doi.org/10.1002/mc.22057.

PMID
23776098
Full Text

Pages