James Abbruzzese, MD

Professor of Medicine
D. C. I. Professor of Medical Oncology
Chief, Division of Medical Oncology
Member of the Duke Cancer Institute
Campus mail 440 Mudd Building, Box 3406, Durham, NC 27710
Email address james.abbruzzese@duke.edu

My research interests include the clinical study and treatment of pancreatic cancer.

In Their Words

Education and Training

  • Resident, Internal Medicine, Johns Hopkins University School of Medicine, 1979 - 1981
  • Intern, Internal Medicine, Johns Hopkins University School of Medicine, 1978 - 1979
  • M.D., University of Chicago, 1978

Publications

Weeks, A. E., J. L. Abbruzzese, and B. Levin. “Current status of chemotherapy for colorectal cancer.” Drug Therapy 19, no. 6 (December 1, 1989): 36–55.

Scholars@Duke

Abbruzzese, J. L., B. Levin, J. A. Ajani, J. S. Faintuch, S. Saks, Y. Z. Patt, C. Edwards, K. Ende, and J. U. Gutterman. “Phase I trial of recombinant human gamma-interferon and recombinant human tumor necrosis factor in patients with advanced gastrointestinal cancer..” Cancer Res 49, no. 14 (July 15, 1989): 4057–61.

PMID
2500234
Scholars@Duke

Abbruzzese, J. L., S. Schmidt, M. N. Raber, J. K. Levy, A. M. Castellanos, S. S. Legha, and I. H. Krakoff. “Phase I trial of 1-(2'-deoxy-2'-fluoro-1-beta-D-arabinofuranosyl)-5-methyluracil (FMAU) terminated by severe neurologic toxicity..” Invest New Drugs 7, no. 2–3 (July 1989): 195–201. https://doi.org/10.1007/bf00170857.

PMID
2793372
Full Text

Ajani, J. A., A. A. Rios, K. Ende, J. L. Abbruzzese, C. Edwards, J. S. Faintuch, S. Saks, J. U. Gutterman, and B. Levin. “Phase I and II studies of the combination of recombinant human interferon-gamma and 5-fluorouracil in patients with advanced colorectal carcinoma..” J Biol Response Mod 8, no. 2 (April 1989): 140–46.

PMID
2499663
Scholars@Duke

Abbruzzese, J. L., and B. Levin. “Treatment of advanced colorectal cancer..” Hematol Oncol Clin North Am 3, no. 1 (March 1989): 135–53.

PMID
2465291
Scholars@Duke

Rich, T. A., L. L. Hughes, J. M. Jessup, D. M. Ota, F. C. Ames, D. C. Hohn, R. G. Martin, J. A. Ajani, and J. L. Abbruzzese. “Conservative management of anal and low rectal cancers with combined modality therapy.” Cancer Bulletin 41, no. 2 (January 1, 1989): 71–74.

Scholars@Duke

Ajani, J. A., P. Goudeau, B. Levin, J. S. Faintuch, J. L. Abbruzzese, B. M. Boman, and M. D. Kanojia. “Phase II study of adriamycin with sequential methotrexate and 5-fluorouracil (AMF) in gastric carcinoma..” Cancer Chemother Pharmacol 24, no. 1 (1989): 41–44. https://doi.org/10.1007/bf00254103.

PMID
2720890
Full Text

Ajani, J. A., J. L. Abbruzzese, P. Goudeau, J. S. Faintuch, A. C. Yeomans, B. M. Boman, C. Nicaise, and B. Levin. “Ifosfamide and mesna: marginally active in patients with advanced carcinoma of the pancreas..” J Clin Oncol 6, no. 11 (November 1988): 1703–7. https://doi.org/10.1200/JCO.1988.6.11.1703.

PMID
3141592
Full Text

Ajani, J. A., J. L. Abbruzzese, J. S. Faintuch, R. Blackburn, B. Levin, and B. M. Boman. “Phase II study of fludarabine phosphate in patients with advanced colorectal carcinoma..” Invest New Drugs 6, no. 1 (April 1988): 47–50. https://doi.org/10.1007/bf00170780.

PMID
2457566
Full Text

Abbruzzese, J. L. “Recent approaches to the systemic therapy of advanced colorectal carcinoma.” Cancer Bulletin 40, no. 4 (January 1, 1988): 238–43.

Scholars@Duke

Pages