James Enlou Tcheng, MD

Professor of Medicine
Professor of Family Medicine and Community Health
Campus mail Duke Box 2708, Durham, NC 27710
Phone (919) 668-8796
Email address tchen001@mc.duke.edu

In addition to my clinical responsibilities as an interventional cardiologist, my research interests include the study of antithrombotic therapies in cardiovascular disease and biomedical informatics and information technologies.

My research is applied (clinical research), primarily focusing on the evaluation of technologies in the clinical arena.

I have participated in numerous clinical trials and have also conducted several multicenter studies, including the EPIC, PROLOG, EPILOG, EPISTENT, IMPACT, IMPACT II, TOTAL, PRIDE, ESPRIT, MEND-1, and ELECT Trials.

My areas of expertise are an outgrowth of my clinical research, and includes use of the new antiplatelet therapeutics in the treatment of coronary artery disease; treatment of unstable angina and acute myocardial infarction; quality assurance and quality improvement; application of informatics and information technology to the delivery of care; and the application of excimer laser coronary angioplasty in the treatment of coronary artery disease.

Key words: angioplasty, excimer laser, platelet glycoproteins, computers, clinical trials.

Education and Training

  • Fellow, Cardiology, Duke University School of Medicine, 1986 - 1988
  • Resident, Internal Medicine, Barnes Hospital, 1983 - 1985
  • Intern, Internal Medicine, Barnes Hospital, 1982 - 1983
  • M.D., Johns Hopkins University, 1982

Publications

Murphy, Shawn N., Anil Dubey, Peter J. Embi, Paul A. Harris, Brent G. Richter, Fran Turisco, Griffin M. Weber, James E. Tcheng, and Diane Keogh. “Current state of information technologies for the clinical research enterprise across academic medical centers..” Clin Transl Sci 5, no. 3 (June 2012): 281–84. https://doi.org/10.1111/j.1752-8062.2011.00387.x.

PMID
22686207
Full Text

Tcheng, James E., and Steven M. Mackay. “Prasugrel versus clopidogrel antiplatelet therapy after acute coronary syndrome: matching treatments with patients..” Am J Cardiovasc Drugs 12, no. 2 (April 1, 2012): 83–91. https://doi.org/10.2165/11594600-000000000-00000.

PMID
22316323
Full Text

Mehta, Rajendra H., Jennifer Yu, Jonathan P. Piccini, James E. Tcheng, Michael E. Farkouh, James Reiffel, Martin Fahy, Roxana Mehran, and Gregg W. Stone. “Prognostic significance of postprocedural sustained ventricular tachycardia or fibrillation in patients undergoing primary percutaneous coronary intervention (from the HORIZONS-AMI Trial)..” Am J Cardiol 109, no. 6 (March 15, 2012): 805–12. https://doi.org/10.1016/j.amjcard.2011.10.043.

PMID
22196782
Full Text

Jolicœur, E Marc, Micheal J. Sketch, Daniel M. Wojdyla, Sean P. Javaheri, Shravan Nosib, Yuliya Lokhnygina, Manesh R. Patel, Linda K. Shaw, and James E. Tcheng. “Percutaneous coronary interventions and cardiovascular outcomes for patients with chronic total occlusions..” Catheter Cardiovasc Interv 79, no. 4 (March 1, 2012): 603–12. https://doi.org/10.1002/ccd.23269.

PMID
21805595
Full Text

Denardo, Scott J., Paul L. Carpinone, David M. Vock, James E. Tcheng, Harry R. Phillips, III, Christopher D. Batich, and Carl J. Pepine. “DAMAGE TO POLYMER SURFACE AND DETACHMENT OF POLYMER FRAGMENTS DURING DELIVERY BALLOON EXPANSION OF DRUG-ELUTING STENTS: A PREVIOUSLY UNRECOGNIZED SOURCE FOR ADVERSE OUTCOMES.” In Journal of the American College of Cardiology, 59:E218–E218. Elsevier BV, 2012. https://doi.org/10.1016/s0735-1097(12)60219-8.

Full Text

Writing Committee to Develop Clinical Data Standards for Peripheral Atherosclerotic Vascular Disease, William S., Mark A. Creager, Michael Belkin, Edward I. Bluth, Donald E. Casey, Seemant Chaturvedi, Michael D. Dake, et al. “2012 ACCF/AHA/ACR/SCAI/SIR/STS/SVM/SVN/SVS key data elements and definitions for peripheral atherosclerotic vascular disease: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Clinical Data Standards (Writing Committee to Develop Clinical Data Standards for Peripheral Atherosclerotic Vascular Disease)..” Circulation 125, no. 2 (January 17, 2012): 395–467. https://doi.org/10.1161/CIR.0b013e31823299a1.

PMID
22144570
Full Text

Creager, Mark A., Michael Belkin, Edward I. Bluth, Donald E. Casey, Seemant Chaturvedi, Michael D. Dake, Jerome L. Fleg, et al. “2012 ACCF/AHA/ACR/SCAI/SIR/STS/SVM/SVN/SVS Key data elements and definitions for peripheral atherosclerotic vascular disease: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Clinical Data Standards (Writing Committee to develop Clinical Data Standards for peripheral atherosclerotic vascular disease)..” J Am Coll Cardiol 59, no. 3 (January 17, 2012): 294–357. https://doi.org/10.1016/j.jacc.2011.10.860.

PMID
22153885
Full Text

Denardo, Scott J., David M. Vock, Carsten M. Schmalfuss, Gregory D. Young, James E. Tcheng, Melvin R. Echols, Karen S. Pieper, and Christopher M. O’Connor. “Baseline Hemodynamics with Cardiac Performance Response to Contrast Media During Diagnostic Cardiac Catheterization Enhances Prediction of Adverse Events in Heart Failure Patients.” Circulation 124, no. 21 (November 22, 2011).

Scholars@Duke

Weintraub, William S., Ronald P. Karlsberg, James E. Tcheng, Jeffrey R. Boris, Alfred E. Buxton, James T. Dove, Gregg C. Fonarow, et al. “ACCF/AHA 2011 key data elements and definitions of a base cardiovascular vocabulary for electronic health records: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Clinical Data Standards..” J Am Coll Cardiol 58, no. 2 (July 5, 2011): 202–22. https://doi.org/10.1016/j.jacc.2011.05.001.

PMID
21652161
Full Text

Weintraub, William S., Ronald P. Karlsberg, James E. Tcheng, Jeffrey R. Boris, Alfred E. Buxton, James T. Dove, Gregg C. Fonarow, et al. “ACCF/AHA 2011 key data elements and definitions of a base cardiovascular vocabulary for electronic health records: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Clinical Data Standards..” Circulation 124, no. 1 (July 5, 2011): 103–23. https://doi.org/10.1161/CIR.0b013e31821ccf71.

PMID
21646493
Full Text

Pages