James Enlou Tcheng, MD

Professor of Medicine
Assistant Dean for Academic Appointments
Professor of Family Medicine and Community Health
Campus mail Duke Box 2708, Durham, NC 27710
Phone (919) 668-8796
Email address tchen001@mc.duke.edu

In addition to my clinical responsibilities as an interventional cardiologist, my research interests include the study of antithrombotic therapies in cardiovascular disease and biomedical informatics and information technologies.

My research is applied (clinical research), primarily focusing on the evaluation of technologies in the clinical arena.

I have participated in numerous clinical trials and have also conducted several multicenter studies, including the EPIC, PROLOG, EPILOG, EPISTENT, IMPACT, IMPACT II, TOTAL, PRIDE, ESPRIT, MEND-1, and ELECT Trials.

My areas of expertise are an outgrowth of my clinical research, and includes use of the new antiplatelet therapeutics in the treatment of coronary artery disease; treatment of unstable angina and acute myocardial infarction; quality assurance and quality improvement; application of informatics and information technology to the delivery of care; and the application of excimer laser coronary angioplasty in the treatment of coronary artery disease.

Key words: angioplasty, excimer laser, platelet glycoproteins, computers, clinical trials.

Education and Training

  • Fellow, Cardiology, Duke University School of Medicine, 1986 - 1988
  • Resident, Internal Medicine, Barnes Hospital, 1983 - 1985
  • Intern, Internal Medicine, Barnes Hospital, 1982 - 1983
  • M.D., Johns Hopkins University, 1982

Grants

Publications

Stack, R. S., R. M. Califf, H. R. Phillips, D. B. Pryor, P. J. Quigley, R. P. Bauman, J. E. Tcheng, and J. C. Greenfield. “Interventional Cardiac Catheterization at Duke Medical Center - The Duke Interventional Cardiac Catheterization Program.” American Journal of Cardiology 62, no. 10 PART II (January 1, 1988).

Scholars@Duke

Stack, R. S., R. M. Califf, H. R. Phillips, D. B. Pryor, P. J. Quigley, R. P. Bauman, J. E. Tcheng, and J. C. Greenfield. “New international technology: The autoperfusion balloon catheter.” American Journal of Cardiology 62, no. 10 PART II (January 1, 1988).

Scholars@Duke

Stack, R. S., R. M. Califf, H. R. Phillips, D. B. Pryor, P. J. Quigley, R. P. Bauman, J. E. Tcheng, and J. C. Greenfield. “Limitations of balloon angioplasty: Possible causes of restenosis.” American Journal of Cardiology 62, no. 10 PART II (January 1, 1988).

Scholars@Duke

Stack, R. S., R. M. Califf, H. R. Phillips, D. B. Pryor, P. J. Quigley, R. P. Bauman, J. E. Tcheng, and J. C. G. Jr. “Balloon angioplasty in acute myocardial infarction - Limitations of thrombolytic therapy when used alone.” American Journal of Cardiology 62, no. 10 PART II (1988): 4F-4F.

Scholars@Duke

Kunkel, T. A., J. E. Tcheng, and R. R. Meyer. “Purification and properties of DNA polymerase-beta from guinea pig liver..” Biochim Biophys Acta 520, no. 2 (September 27, 1978): 302–16. https://doi.org/10.1016/0005-2787(78)90229-0.

PMID
708739
Full Text

Mosbaugh, D. W., T. A. Kunkel, D. M. Stalker, J. E. Tcheng, and R. R. Meyer. “Novikoff hepatoma deoxyribonucleic acid polymerase. Sensitivity of the beta-polymerase to sulfhydryl blocking agents..” Nucleic Acids Res 3, no. 9 (September 1976): 2341–52. https://doi.org/10.1093/nar/3.9.2341.

PMID
9624
Full Text

Pages