James Enlou Tcheng, MD

Professor of Medicine
Assistant Dean for Academic Appointments
Professor of Family Medicine and Community Health
Campus mail Duke Box 2708, Durham, NC 27710
Phone (919) 668-8796
Email address tchen001@mc.duke.edu

In addition to my clinical responsibilities as an interventional cardiologist, my research interests include the study of antithrombotic therapies in cardiovascular disease and biomedical informatics and information technologies.

My research is applied (clinical research), primarily focusing on the evaluation of technologies in the clinical arena.

I have participated in numerous clinical trials and have also conducted several multicenter studies, including the EPIC, PROLOG, EPILOG, EPISTENT, IMPACT, IMPACT II, TOTAL, PRIDE, ESPRIT, MEND-1, and ELECT Trials.

My areas of expertise are an outgrowth of my clinical research, and includes use of the new antiplatelet therapeutics in the treatment of coronary artery disease; treatment of unstable angina and acute myocardial infarction; quality assurance and quality improvement; application of informatics and information technology to the delivery of care; and the application of excimer laser coronary angioplasty in the treatment of coronary artery disease.

Key words: angioplasty, excimer laser, platelet glycoproteins, computers, clinical trials.

Education and Training

  • Fellow, Cardiology, Duke University School of Medicine, 1986 - 1988
  • Resident, Internal Medicine, Barnes Hospital, 1983 - 1985
  • Intern, Internal Medicine, Barnes Hospital, 1982 - 1983
  • M.D., Johns Hopkins University, 1982

Grants

Publications

Rabbani, Leroy E., Srinivas Iyengar, George D. Dangas, Cindy L. Grines, David A. Cox, Eulogio Garcia, James E. Tcheng, et al. “Impact of thienopyridine administration prior to primary stenting in acute myocardial infarction..” J Interv Cardiol 22, no. 4 (August 2009): 378–84. https://doi.org/10.1111/j.1540-8183.2009.00474.x.

PMID
19496901
Full Text

Madan, Mina, Janarthan Nikhil, Anne S. Hellkamp, Karen S. Pieper, Marino Labinaz, E. A. Cohen, Christopher E. Buller, et al. “Effect of operator and institutional volume on clinical outcomes after percutaneous coronary interventions performed in Canada and the United States: a brief report from the Enhanced Suppression of the Platelet glycoprotein IIb/IIIa Receptor with Integrilin Therapy (ESPRIT) study..” Can J Cardiol 25, no. 8 (August 2009): e269–72. https://doi.org/10.1016/s0828-282x(09)70120-5.

PMID
19668787
Full Text

Nikolsky, Eugenia, Roxana Mehran, H Mehrdad Sadeghi, Cindy L. Grines, David A. Cox, Eulogio Garcia, James E. Tcheng, et al. “Prognostic impact of blood transfusion after primary angioplasty for acute myocardial infarction: analysis from the CADILLAC (Controlled Abciximab and Device Investigation to Lower Late Angioplasty Complications) Trial..” Jacc Cardiovasc Interv 2, no. 7 (July 2009): 624–32. https://doi.org/10.1016/j.jcin.2009.05.004.

PMID
19628185
Full Text

Tcheng, J. E., and David A. Cox. “Primary Coronary Intervention: The Technical Approach.” In Primary Angioplasty in Acute Myocardial Infarction, 47–47. Springer Science & Business Media, 2009.

Scholars@Duke

Denardo, Scott J., Mustafa H. M. Hassan, Richard S. Schofield, James A. Hill, Keith E. Davis, and James E. Tcheng. “Percutaneous Coronary Intervention for Treatment of Symptomatic Ischemic Heart Failure With Normal Left Ventricular Systolic Function.” Journal of the American College of Cardiology 53, no. 10 (March 10, 2009): A51–A51.

Scholars@Duke

Tcheng, James E., Ing Haan Lim, Shankar Srinivasan, Joseph Jozic, C Michael Gibson, J Conor O’Shea, Joseph A. Puma, and Daniel I. Simon. “Stent parameters predict major adverse clinical events and the response to platelet glycoprotein IIb/IIIa blockade: findings of the ESPRIT trial..” Circ Cardiovasc Interv 2, no. 1 (February 2009): 43–51. https://doi.org/10.1161/CIRCINTERVENTIONS.108.809285.

PMID
20031692
Full Text

Lansky, Alexandra J., Yoshihiro Tsuchiya, Micheal Brener, Roxana Mehran, Ecaterina Cristea, Cody Pietras, Cindy L. Grines, et al. “Comparison between ticlopidine and clopidogrel in patients undergoing primary stenting in acute myocardial infarction: results from the CADILLAC trial..” Catheter Cardiovasc Interv 72, no. 7 (December 1, 2008): 917–24. https://doi.org/10.1002/ccd.21714.

PMID
19016469
Full Text

Mehta, Rajandra H., Kishore J. Harjai, Judy A. Boura, James E. Tcheng, Gregg W. Stone, and Cindy L. Grines. “Is Balloon Angioplasty without Stent Placement Adequate far Patients In Whom Early Coronary Artery Bypass Surgery Is Planned after Primary Percutaneous Coronary Intervention?.” In Circulation, 118:S633–S633. LIPPINCOTT WILLIAMS & WILKINS, 2008.

Scholars@Duke

Kruk, M., C. E. Buller, V. Dzavik, G. B. J. Mancini, P. Kurray, J. E. Tcheng, V. Menon, S. A. Forman, G. A. Lamas, and J. S. Hochman. “Late recanalization of infarct related artery has no impact on clinical outcomes regardless of ejection fraction: Results from the Occluded Artery Trial (OAT).” European Heart Journal 29 (September 1, 2008): 679–679.

Scholars@Duke

Casterella, Peter J., and James E. Tcheng. “Review of the 2005 American College of Cardiology, American Heart Association, and Society for Cardiovascular Interventions guidelines for adjunctive pharmacologic therapy during percutaneous coronary interventions: practical implications, new clinical data, and recommended guideline revisions..” Am Heart J 155, no. 5 (May 2008): 781–90. https://doi.org/10.1016/j.ahj.2007.12.014.

PMID
18440324
Full Text

Pages