James Enlou Tcheng, MD

Professor of Medicine
Professor of Family Medicine and Community Health
Campus mail Duke Box 2708, Durham, NC 27710
Phone (919) 668-8796
Email address tchen001@mc.duke.edu

In addition to my clinical responsibilities as an interventional cardiologist, my research interests include the study of antithrombotic therapies in cardiovascular disease and biomedical informatics and information technologies.

My research is applied (clinical research), primarily focusing on the evaluation of technologies in the clinical arena.

I have participated in numerous clinical trials and have also conducted several multicenter studies, including the EPIC, PROLOG, EPILOG, EPISTENT, IMPACT, IMPACT II, TOTAL, PRIDE, ESPRIT, MEND-1, and ELECT Trials.

My areas of expertise are an outgrowth of my clinical research, and includes use of the new antiplatelet therapeutics in the treatment of coronary artery disease; treatment of unstable angina and acute myocardial infarction; quality assurance and quality improvement; application of informatics and information technology to the delivery of care; and the application of excimer laser coronary angioplasty in the treatment of coronary artery disease.

Key words: angioplasty, excimer laser, platelet glycoproteins, computers, clinical trials.

Education and Training

  • Fellow, Cardiology, Duke University School of Medicine, 1986 - 1988
  • Resident, Internal Medicine, Barnes Hospital, 1983 - 1985
  • Intern, Internal Medicine, Barnes Hospital, 1982 - 1983
  • M.D., Johns Hopkins University, 1982

Publications

Dery, Jean-Pierre, Jeffrey Griffin, Karen S. Pieper, Robert A. Harrington, and James E. Tcheng. “Comparison of outcomes between patients undergoing percutaneous coronary stent implantation with eptifibatide and abciximab: An analysis using propensity score methods.” In American Journal of Cardiology, 100:41L-42L. EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC, 2007.

Scholars@Duke

Rabbani, LeRoy E., Jennifer Stant, Cindy L. Grines, David A. Cox, Eulogio Garcia, James E. Tcheng, John J. Griffin, et al. “Impact of thienopyridine administration prior to primary stealing in acute myocardial infarction.” In American Journal of Cardiology, 100:213L-213L. EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC, 2007.

Scholars@Duke

Dery, J., J. Griffin, K. S. Pieper, R. A. Harrington, and J. E. Tcheng. “Comparison of outcomes between patients undergoing percutaneous coronary stent implantation with eptifibatide and abciximab: An analysis using propensity score methods.” Canadian Journal of Cardiology 23 (October 1, 2007): 59C-59C.

Scholars@Duke

Dery, J. P., J. Griffin, K. S. Pieper, R. A. Harrington, and J. E. Tcheng. “Comparison of outcomes between patients undergoing percutaneous coronary stent implantation with eptifibatide and abciximab: an analysis using propensity score methods.” European Heart Journal 28 (September 1, 2007): 184–184.

Scholars@Duke

Dery, Jean-Pierre, Mark E. Campbell, Jasmine Mathias, Karen S. Pieper, Robert A. Harrington, Mina Madan, C Michael Gibson, et al. “Complementary effects of thienopyridine pretreatment and platelet glycoprotein IIb/IIIa integrin blockade with eptifibatide in coronary stent intervention; results from the ESPRIT trial..” Catheter Cardiovasc Interv 70, no. 1 (July 1, 2007): 43–50. https://doi.org/10.1002/ccd.21059.

PMID
17203469
Full Text

Sorajja, Paul, Bernard J. Gersh, David A. Cox, Michael G. McLaughlin, Peter Zimetbaum, Costantino Costantini, Thomas Stuckey, et al. “Impact of multivessel disease on reperfusion success and clinical outcomes in patients undergoing primary percutaneous coronary intervention for acute myocardial infarction..” Eur Heart J 28, no. 14 (July 2007): 1709–16. https://doi.org/10.1093/eurheartj/ehm184.

PMID
17556348
Full Text

Nikolsky, Eugenia, Cindy L. Grines, David A. Cox, Eulogio Garcia, James E. Tcheng, Mehrdad Sadeghi, Roxana Mehran, Alexandra J. Lansky, Yingbo Na, and Gregg W. Stone. “Impact of baseline platelet count in patients undergoing primary percutaneous coronary intervention in acute myocardial infarction (from the CADILLAC trial)..” Am J Cardiol 99, no. 8 (April 15, 2007): 1055–61. https://doi.org/10.1016/j.amjcard.2006.11.066.

PMID
17437727
Full Text

Prasad, Abhiram, Gregg W. Stone, Thomas D. Stuckey, Costantino O. Costantini, Roxana Mehran, Eulogio Garcia, James E. Tcheng, et al. “Relation between leucocyte count, myonecrosis, myocardial perfusion, and outcomes following primary angioplasty..” Am J Cardiol 99, no. 8 (April 15, 2007): 1067–71. https://doi.org/10.1016/j.amjcard.2006.11.063.

PMID
17437729
Full Text

Radford, Martha J., Paul A. Heidenreich, Steven R. Bailey, David C. Goff, Frederick L. Grover, Edward P. Havranek, Richard E. Kuntz, et al. “ACC/AHA 2007 methodology for the development of clinical data standards: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Data Standards..” J Am Coll Cardiol 49, no. 7 (February 20, 2007): 830–37. https://doi.org/10.1016/j.jacc.2007.01.002.

PMID
17306718
Full Text

Harjai, Kishore J., Gregg W. Stone, Cindy L. Grines, David A. Cox, Eulogio Garcia, James E. Tcheng, Yingbo Na, et al. “Usefulness of routine unfractionated heparin infusion following primary percutaneous coronary intervention for acute myocardial infarction in patients not receiving glycoprotein IIb/IIIa inhibitors..” Am J Cardiol 99, no. 2 (January 15, 2007): 202–7. https://doi.org/10.1016/j.amjcard.2006.07.084.

PMID
17223419
Full Text

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