James Wharam, MBBCh

Instructor in the Department of Medicine
Campus mail Box 31256 Med Ctr, Durham, NC 27710
Phone (919) 684-8111
Email address james.wharam@duke.edu

Dr. Frank Wharam is a general internist and health policy researcher. He studies the impact of national and state policies on the health outcomes of chronically ill and vulnerable populations. His research often examines effects of health insurance benefit designs such as value-based, consumer-directed, and high-deductible health plans. Dr. Wharam also focuses on interventions that affect people with substance use disorders, diabetes, obesity, mental illness, and respiratory diseases. Other interests include the adverse effects of wasteful health care spending on medical and non-medical outcomes. He has expertise in rigorous quasi-experiment research designs, causal inference in observational data, and large claims data analyses.

Dr. Wharam is core faculty member in the Margolis Center and Professor of Medicine in the Division of General Internal Medicine. He directs a new center devoted to analyzing large-scale health policy effects in order to inform a more efficient and equitable health care system.   

Dr. Wharam joins Duke after 17 years at the Harvard Medical School Department of Population Medicine. There he held the Martin Robison Delany endowed chair and was Director of the Division of Health Policy and Insurance Research. Before Harvard, he completed Internal Medicine residency at Duke in 2004. 

Education and Training

  • Fellowship, Medical Ethics, Harvard Medical School, 2005 - 2006
  • Fellowship, Internal Medicine, Harvard Medical School, 2004 - 2007
  • Residency, Internal Medicine, Duke University, 2001 - 2004
  • M.B.B.Ch., University College Dublin (Ireland), 2001

Publications

Wharam, J Frank, Jamie Wallace, Stephanie Argetsinger, Fang Zhang, Christine Y. Lu, Tomasz P. Stryjewski, Dennis Ross-Degnan, and Joseph P. Newhouse. “Diabetes Microvascular Disease Diagnosis and Treatment After High-Deductible Health Plan Enrollment.” Diabetes Care, September 29, 2021. https://doi.org/10.2337/dc21-0407.

PMID
34588211
Full Text

Chou, Shih-Chuan, Arthur S. Hong, Scott G. Weiner, and J Frank Wharam. “Impact of High-Deductible Health Plans on Emergency Department Patients With Nonspecific Chest Pain and Their Subsequent Care.” Circulation 144, no. 5 (August 3, 2021): 336–49. https://doi.org/10.1161/CIRCULATIONAHA.120.052501.

PMID
34176279
Full Text

Chou, Shih-Chuan, Arthur S. Hong, Scott G. Weiner, and J Frank Wharam. “High-deductible health plans and low-value imaging in the emergency department.” Health Serv Res 56, no. 4 (August 2021): 709–20. https://doi.org/10.1111/1475-6773.13569.

PMID
33025604
Full Text

Lu, Christine Y., Alisa B. Busch, Fang Zhang, Jeanne M. Madden, Matthew X. Callahan, Robert F. LeCates, Jamie Wallace, et al. “Impact of High-Deductible Health Plans on Medication Use Among Individuals With Bipolar Disorder.” Psychiatr Serv 72, no. 8 (August 1, 2021): 926–34. https://doi.org/10.1176/appi.ps.202000362.

PMID
33971720
Full Text

Galbraith, Alison A., Dennis Ross-Degnan, Fang Zhang, Ann Chen Wu, Anna Sinaiko, Alon Peltz, Xin Xu, Jamie Wallace, and J Frank Wharam. “Controller Medication Use and Exacerbations for Children and Adults With Asthma in High-Deductible Health Plans.” Jama Pediatr 175, no. 8 (August 1, 2021): 807–16. https://doi.org/10.1001/jamapediatrics.2021.0747.

PMID
33970186
Full Text

Galbraith, Alison A., Dennis Ross-Degnan, Fang Zhang, Ann Chen Wu, Anna Sinaiko, Robert F. LeCates, Jamie Wallace, Alon Peltz, and J Frank Wharam. “Association of Controller Use and Exacerbations for High-Deductible Plan Enrollees with and without Family Members with Asthma.” Ann Am Thorac Soc 18, no. 7 (July 2021): 1255–60. https://doi.org/10.1513/AnnalsATS.202008-1084RL.

PMID
33529568
Full Text

Lewis, Kristina H., David E. Arterburn, Fang Zhang, Katherine Callaway, Jamie Wallace, Adolfo Fernandez, Dennis Ross-Degnan, and James F. Wharam. “Comparative Effectiveness of Vertical Sleeve Gastrectomy Versus Roux-en-Y Gastric Bypass for Diabetes Treatment: A Claims-based Cohort Study.” Ann Surg 273, no. 5 (May 1, 2021): 940–48. https://doi.org/10.1097/SLA.0000000000003391.

PMID
31205064
Full Text

Wharam, J Frank, Jamie Wallace, Robert F. LeCates, Jeanne M. Madden, Fang Zhang, Dennis Ross-Degnan, and Christine Y. Lu. “Out-of-Pocket Spending Inequity Among High-Deductible Health Plan Members with Bipolar Disorder.” J Gen Intern Med, April 12, 2021. https://doi.org/10.1007/s11606-021-06773-x.

PMID
33846944
Full Text

Madden, Jeanne M., Carina Araujo-Lane, Phyllis Foxworth, Christine Y. Lu, J Frank Wharam, Alisa B. Busch, Stephen B. Soumerai, and Dennis Ross-Degnan. “Experiences of health care costs among people with employer-sponsored insurance and bipolar disorder.” J Affect Disord 281 (February 15, 2021): 41–50. https://doi.org/10.1016/j.jad.2020.10.033.

PMID
33290926
Full Text

Madden, Jeanne M., Phyllis M. Foxworth, Dennis Ross-Degnan, Kimberly G. Allen, Alisa B. Busch, Matthew X. Callahan, Christine Y. Lu, and James F. Wharam. “Integrating Stakeholder Engagement With Claims-Based Research on Health Insurance Design and Bipolar Disorder.” Psychiatr Serv 72, no. 2 (February 1, 2021): 186–94. https://doi.org/10.1176/appi.ps.202000177.

PMID
33167814
Full Text

Pages