Jiangbo Wang, PhD

Publications

Wang, Jiangbo, Xiu-Rong Ren, Hailan Piao, Shengli Zhao, Takuya Osada, Richard T. Premont, Robert A. Mook, Michael A. Morse, Herbert Kim Lyerly, and Wei Chen. “Niclosamide-induced Wnt signaling inhibition in colorectal cancer is mediated by autophagy..” The Biochemical Journal 476, no. 3 (February 8, 2019): 535–46. https://doi.org/10.1042/bcj20180385.

PMID
30635359
Full Text

Wang, Jiangbo, Robert A. Mook, Xiu-Rong Ren, Qingfu Zhang, Genevieve Jing, Min Lu, Ivan Spasojevic, H Kim Lyerly, David Hsu, and Wei Chen. “Identification of DK419, a potent inhibitor of Wnt/β-catenin signaling and colorectal cancer growth..” Bioorganic & Medicinal Chemistry 26, no. 20 (November 2018): 5435–42. https://doi.org/10.1016/j.bmc.2018.09.016.

PMID
30274939
Full Text

Mook, Robert A., Xiu-Rong Ren, Jiangbo Wang, Hailan Piao, Larry S. Barak, H. Kim Lyerly, and Wei Chen. “Benzimidazole inhibitors from the Niclosamide chemotype inhibit Wnt/β-catenin signaling with selectivity over effects on ATP homeostasis..” Bioorganic & Medicinal Chemistry 25, no. 6 (March 2017): 1804–16. https://doi.org/10.1016/j.bmc.2017.01.046.

PMID
28233680
Full Text

Ren, X. R., J. Wang, T. Osada, R. A. Mook, M. A. Morse, L. S. Barak, H. K. Lyerly, and W. Chen. “Perhexiline promotes HER3 ablation through receptor internalization and inhibits tumor growth..” Breast Cancer Research : Bcr 17, no. 1 (December 2015).

PMID
25778364
Scholars@Duke

Mook, Robert A., Jiangbo Wang, Xiu-Rong Ren, Minyong Chen, Ivan Spasojevic, Larry S. Barak, H Kim Lyerly, and Wei Chen. “Structure-activity studies of Wnt/β-catenin inhibition in the Niclosamide chemotype: Identification of derivatives with improved drug exposure..” Bioorg Med Chem 23, no. 17 (September 1, 2015): 5829–38. https://doi.org/10.1016/j.bmc.2015.07.001.

PMID
26272032
Full Text

Barak, Larry S., Yushi Bai, Joshua C. Snyder, Jiangbo Wang, Wei Chen, and Marc G. Caron. “Triphenylmethane dye activation of beta-arrestin..” Biochemistry 52, no. 32 (August 2013): 5403–14. https://doi.org/10.1021/bi400217r.

PMID
23865508
Full Text

Lu, Jiuyi, Minyong Chen, Xiu-Rong Ren, Jiangbo Wang, H Kim Lyerly, Larry Barak, and Wei Chen. “Regulation of hedgehog signaling by Myc-interacting zinc finger protein 1, Miz1..” Plos One 8, no. 5 (January 2013). https://doi.org/10.1371/journal.pone.0063353.

PMID
23671675
Full Text

Wang, Jiangbo, Robert A. Mook, Jiuyi Lu, David M. Gooden, Anthony Ribeiro, Anchen Guo, Larry S. Barak, H Kim Lyerly, and Wei Chen. “Identification of a novel Smoothened antagonist that potently suppresses Hedgehog signaling..” Bioorganic & Medicinal Chemistry 20, no. 22 (November 2012): 6751–57. https://doi.org/10.1016/j.bmc.2012.09.030.

PMID
23063522
Full Text

Wang, Jiangbo, Jiuyi Lu, Robert A. Mook, Min Zhang, Shengli Zhao, Larry S. Barak, Jonathan H. Freedman, H Kim Lyerly, and Wei Chen. “The insecticide synergist piperonyl butoxide inhibits hedgehog signaling: assessing chemical risks..” Toxicological Sciences : An Official Journal of the Society of Toxicology 128, no. 2 (August 2012): 517–23. https://doi.org/10.1093/toxsci/kfs165.

PMID
22552772
Full Text

Pages