Jiangbo Wang, PhD

Publications

Wang, J, Mook, RA, Ren, X-R, Zhang, Q, Jing, G, Lu, M, Spasojevic, I, Lyerly, HK, Hsu, D, and Chen, W. "Identification of DK419, a potent inhibitor of Wnt/β-catenin signaling and colorectal cancer growth." Bioorganic & Medicinal Chemistry (September 17, 2018).

PMID
30274939
Full Text

Chen, W, Mook, RA, Premont, RT, and Wang, J. "Niclosamide: Beyond an antihelminthic drug." Cellular signalling 41 (January 2018): 89-96. (Review)

PMID
28389414
Full Text

Mook, RA, Ren, X-R, Wang, J, Piao, H, Barak, LS, Kim Lyerly, H, and Chen, W. "Benzimidazole inhibitors from the Niclosamide chemotype inhibit Wnt/β-catenin signaling with selectivity over effects on ATP homeostasis." Bioorganic & medicinal chemistry 25, no. 6 (March 2017): 1804-1816.

PMID
28233680
Full Text

Ren, XR, Wang, J, Osada, T, Mook, RA, Morse, MA, Barak, LS, Lyerly, HK, and Chen, W. "Perhexiline promotes HER3 ablation through receptor internalization and inhibits tumor growth." Breast cancer research : BCR 17, no. 1 (December 2015): 528-.

PMID
25778364
Scholars@Duke

Mook, RA, Wang, J, Ren, X-R, Chen, M, Spasojevic, I, Barak, LS, Lyerly, HK, and Chen, W. "Structure-activity studies of Wnt/β-catenin inhibition in the Niclosamide chemotype: Identification of derivatives with improved drug exposure." Bioorganic & Medicinal Chemistry 23, no. 17 (September 2015): 5829-5838.

PMID
26272032
Full Text

Barak, LS, Bai, Y, Snyder, JC, Wang, J, Chen, W, and Caron, MG. "Triphenylmethane dye activation of beta-arrestin." Biochemistry 52, no. 32 (August 2013): 5403-5414.

PMID
23865508
Full Text

Lu, J, Chen, M, Ren, X-R, Wang, J, Lyerly, HK, Barak, L, and Chen, W. "Regulation of hedgehog signaling by Myc-interacting zinc finger protein 1, Miz1. (Published online)" PLoS One 8, no. 5 (2013): e63353-.

PMID
23671675
Full Text

Wang, J, Mook, RA, Lu, J, Gooden, DM, Ribeiro, A, Guo, A, Barak, LS, Lyerly, HK, and Chen, W. "Identification of a novel Smoothened antagonist that potently suppresses Hedgehog signaling." Bioorg Med Chem 20, no. 22 (November 15, 2012): 6751-6757.

PMID
23063522
Full Text

Wang, J, Lu, J, Mook, RA, Zhang, M, Zhao, S, Barak, LS, Freedman, JH, Lyerly, HK, and Chen, W. "The insecticide synergist piperonyl butoxide inhibits hedgehog signaling: assessing chemical risks." Toxicological Sciences : an Official Journal of the Society of Toxicology 128, no. 2 (August 2012): 517-523.

PMID
22552772
Full Text

Ren, X-R, Wei, J, Lei, G, Wang, J, Lu, J, Xia, W, Spector, N, Barak, LS, Clay, TM, Osada, T, Hamilton, E, Blackwell, K, Hobeika, AC, Morse, MA, Lyerly, HK, and Chen, W. "Polyclonal HER2-specific antibodies induced by vaccination mediate receptor internalization and degradation in tumor cells. (Published online)" Breast Cancer Res 14, no. 3 (June 7, 2012): R89-.

PMID
22676470
Full Text

Pages