John J. Strouse, MD, PhD

Associate Professor of Medicine
Associate Professor in the Department of Pediatrics
Email address john.strouse@duke.edu

My research has focused on the epidemiology, risk factors, and prevention of the pulmonary and central nervous system complications of sickle cell disease and includes retrospective and prospective cohort studies and clinical trials.  I received my Ph.D. in clinical investigation from the Johns Hopkins Bloomberg School of Public Health for a series of studies to identify predictors of cognitive function in children with sickle cell disease.  This work has expanded to the evaluation of the interaction between environment and disease in both children and adults with sickle cell disease.  My other research interests include the application of large clinical, research, and administrative databases to the study of rare hematological diseases and interventions to improve quality of and access to care for sickle cell disease. I serve on the American Society of Hematology Sickle Cell Taskforce and Sickle Cell Pain Guideline Panel and am co-chair of the American Society of Hematology Healthcare Professional Education and Training Work Group.

 

Education and Training

  • Fellow in Pediatric Hematology, Nci, National Institutes of Health, 2001 - 2004
  • Fellow in Pediatric Hematology/Oncology, Johns Hopkins University, 2001 - 2004
  • Fellow in Hematology, Nhlbi, National Institutes of Health, 2000 - 2004
  • Combined Internal Medicine/Pediatrics Residency, University of Rochester, 1996 - 2000
  • Ph.D., Johns Hopkins University, 2009
  • M.D., Johns Hopkins University School of Medicine, 1996

Publications

Strouse, John J., Sophie Lanzkron, Mary Catherine Beach, Carlton Haywood, Haeseong Park, Catherine Witkop, Renee F. Wilson, Eric B. Bass, and Jodi B. Segal. “Hydroxyurea for sickle cell disease: a systematic review for efficacy and toxicity in children.” Pediatrics 122, no. 6 (December 2008): 1332–42. https://doi.org/10.1542/peds.2008-0441.

PMID
19047254
Full Text

Strouse, John J., Joshua Field, Regina D. Crawford, and Sophie Lanzkron. “Antecedent Transfusion and Primary Hemorrhagic Stroke in Adults with Sickle Cell Disease.” Blood 112, no. 11 (November 16, 2008): 512–512.

Scholars@Duke

Lanzkron, Sophie, John J. Strouse, Renee Wilson, Mary Catherine Beach, Carlton Haywood, HaeSong Park, Catherine Witkop, Eric B. Bass, and Jodi B. Segal. “Systematic review: Hydroxyurea for the treatment of adults with sickle cell disease.” Ann Intern Med 148, no. 12 (June 17, 2008): 939–55. https://doi.org/10.7326/0003-4819-148-12-200806170-00221.

PMID
18458272
Full Text

Finberg, Karin E., Matthew M. Heeney, Dean R. Campagna, Yeşim Aydinok, Howard A. Pearson, Kip R. Hartman, Mary M. Mayo, et al. “Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA).” Nat Genet 40, no. 5 (May 2008): 569–71. https://doi.org/10.1038/ng.130.

PMID
18408718
Full Text

Gamper, Christopher J., Clifford M. Takemoto, Jeffrey Schowinsky, Michael J. Borowitz, Marshall S. Horwitz, and John J. Strouse. “Lymphadenopathy as the primary manifestation of malignant transformation in two patients with severe congenital neutropenia.” Pediatr Blood Cancer 50, no. 5 (May 2008): 1072–75. https://doi.org/10.1002/pbc.21485.

PMID
18213714
Full Text

Strouse, John J., Clifford M. Takemoto, Jeffrey R. Keefer, Gregory J. Kato, and James F. Casella. “Corticosteroids and increased risk of readmission after acute chest syndrome in children with sickle cell disease.” Pediatr Blood Cancer 50, no. 5 (May 2008): 1006–12. https://doi.org/10.1002/pbc.21336.

PMID
17849474
Full Text

Beach, M. C., C. Haywood, S. Lanzkron, J. Strouse, R. F. Wilson, H. Park, C. Witkop, E. Bass, and J. Segal. “Effective pain management for patients with sickle cell vaso-occlusive crisis: A systematic review of barriers and interventions to improve quality.” In Journal of General Internal Medicine, 23:295–96. SPRINGER, 2008.

Scholars@Duke

Segal, Jodi B., John J. Strouse, Mary Catherine Beach, Carlton Haywood, Catherine Witkop, Haeseong Park, Renee F. Wilson, Eric B. Bass, and Sophie Lanzkron. “Hydroxyurea for the treatment of sickle cell disease.” Evid Rep Technol Assess (Full Rep), no. 165 (March 2008): 1–95.

PMID
18457478
Scholars@Duke

Strouse, John J., Carlton Haywood, and Sophie Lanzkron. “Predictors of In-Hospital Mortality and Charges in Sickle Cell Disease: Results from the California Discharge Databases 1998–2005.” In Blood, 110:432–432. American Society of Hematology, 2007. https://doi.org/10.1182/blood.v110.11.432.432.

Full Text

Strouse, John J., Joshua J. Field, and Sophie Lanzkron. “Risk factors for primary hemorrhagic stroke in adults with sickle cell disease.” Blood 110, no. 11 (November 16, 2007): 19B-20B.

Scholars@Duke

Pages