John J. Strouse, MD, PhD

Associate Professor of Medicine
Associate Professor in the Department of Pediatrics
Email address john.strouse@duke.edu

My research has focused on the epidemiology, risk factors, and prevention of the pulmonary and central nervous system complications of sickle cell disease and includes retrospective and prospective cohort studies and clinical trials.  I received my Ph.D. in clinical investigation from the Johns Hopkins Bloomberg School of Public Health for a series of studies to identify predictors of cognitive function in children with sickle cell disease.  This work has expanded to the evaluation of the interaction between environment and disease in both children and adults with sickle cell disease.  My other research interests include the application of large clinical, research, and administrative databases to the study of rare hematological diseases and interventions to improve quality of and access to care for sickle cell disease. I serve on the American Society of Hematology Sickle Cell Taskforce and Sickle Cell Pain Guideline Panel and am co-chair of the American Society of Hematology Healthcare Professional Education and Training Work Group.

 

Education and Training

  • Fellow in Pediatric Hematology, Nci, National Institutes of Health, 2001 - 2004
  • Fellow in Pediatric Hematology/Oncology, Johns Hopkins University, 2001 - 2004
  • Fellow in Hematology, Nhlbi, National Institutes of Health, 2000 - 2004
  • Combined Internal Medicine/Pediatrics Residency, University of Rochester, 1996 - 2000
  • Ph.D., Johns Hopkins University, 2009
  • M.D., Johns Hopkins University School of Medicine, 1996

Publications

Reller, M. E., C. Bodinayake, A. Nagahawatte, V. Devasiri, W. Kodikara-Arachichi, J. J. Strouse, J. E. Flom, T. Østbye, C. W. Woods, and J. S. Dumler. “Unsuspected rickettsioses among patients with acute febrile Illness, Sri Lanka, 2007.” Emerging Infectious Diseases 18, no. 5 (2012): 825–29. https://doi.org/10.3201/eid1805/111563.

Full Text

Strouse, John J., Sophie Lanzkron, and Victor Urrutia. “The epidemiology, evaluation and treatment of stroke in adults with sickle cell disease..” Expert Rev Hematol 4, no. 6 (December 2011): 597–606. https://doi.org/10.1586/ehm.11.61.

PMID
22077524
Full Text

Wun, Ted, Charles L. Knupp, Lillian E. McMahon, John J. Strouse, Chunmei Zhou, Lori E. Heath, Chuke E. Nwachuku, Joseph A. Jakubowski, Kenneth J. Winters, and Jeffrey S. Riesmeyer. “Biomarkers of Hemostatic Activation in a Randomized, Double-Blind, Phase 2 Study of Prasugrel Compared to Placebo in Adults with Sickle Cell Disease.” In Blood, 118:931–32. AMER SOC HEMATOLOGY, 2011.

Scholars@Duke

Bembea, Melania M., William Savage, John J. Strouse, Jamie McElrath Schwartz, Ernest Graham, Carol B. Thompson, and Allen Everett. “Glial fibrillary acidic protein as a brain injury biomarker in children undergoing extracorporeal membrane oxygenation..” Pediatr Crit Care Med 12, no. 5 (September 2011): 572–79. https://doi.org/10.1097/PCC.0b013e3181fe3ec7.

PMID
21057367
Full Text

Reller, Megan E., Champika Bodinayake, Ajith Nagahawatte, Vasantha Devasiri, Wasantha Kodikara-Arachichi, John J. Strouse, Judith E. Flom, J Stephen Dumler, and Christopher W. Woods. “Leptospirosis as frequent cause of acute febrile illness in southern Sri Lanka..” Emerg Infect Dis 17, no. 9 (September 2011): 1678–84. https://doi.org/10.3201/eid1709.100915.

PMID
21888794
Full Text

Bundy, David G., John J. Strouse, James F. Casella, and Marlene R. Miller. “Urgency of emergency department visits by children with sickle cell disease: a comparison of 3 chronic conditions..” Acad Pediatr 11, no. 4 (July 2011): 333–41. https://doi.org/10.1016/j.acap.2011.04.006.

PMID
21764017
Full Text

Raabe, Eric H., Jeffrey R. Keefer, Sally E. Mitchell, Kelvin Hong, Marc DiFazio, and John J. Strouse. “Subtotal splenic embolization is a safe and effective treatment for isolated splenic vascular tumors associated with consumptive coagulopathy..” J Pediatr Hematol Oncol 33, no. 5 (July 2011): 383–86. https://doi.org/10.1097/MPH.0b013e3182172515.

PMID
21606851
Full Text

Qin, Qin, John J. Strouse, and Peter C. M. van Zijl. “Fast measurement of blood T1 in the human jugular vein at 3 Tesla..” Magn Reson Med 65, no. 5 (May 2011): 1297–1304. https://doi.org/10.1002/mrm.22723.

PMID
21500258
Full Text

Williams, Lisa M., Zongming Fu, Pratima Dulloor, Kun Yan, John J. Strouse, William Savage, Emily Barron-Casella, et al. “Identification of Thrombospondin-1 and L-Selectin as Potential Plasma Biomarkers of Silent Cerebral Infarct In Children with Sickle Cell Disease Using a Proteomic-Based Approach.” In Blood, 116:119–119. AMER SOC HEMATOLOGY, 2010.

Scholars@Duke

Vichinsky, Elliott, Lynne Neumayr, Jeffrey I. Gold, Michael W. Weiner, Jeffrey Kasten, Diana Truran, Cathie Snyder, et al. “A Randomized Trial of the Safety and Benefit of Transfusion Vs. Standard Care In the Prevention of Sickle Cell-Related Complications In Adults: a Preliminary Report From the Phase II NHLBI Comprehensive Sickle Cell Centers (CSCC) Study of Neuropsychological Dysfunction and Neuroimaging Abnormalities In Neurologically Intact Adult Patients with Sickle Cell Disease.” In Blood, 116:1321–1321. AMER SOC HEMATOLOGY, 2010.

Scholars@Duke

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