John Wiley Williams, MD

Professor of Medicine
Professor of Psychiatry and Behavioral Sciences
Campus mail 200 Morris Street, 3rd Floor, Durham, NC 27701
Phone (919) 684-7611

John Williams, MD, MHS, is a Professor of Medicine at Duke University Medical Center and a past recipient of VA Health Services Career Development and a Robert Wood Johnson Foundation Generalist Faculty Scholar Awards. He received his bachelor and MD degrees from the University of North Carolina. Dr. Williams completed residency training at the University of Iowa and a research fellowship at Duke University. He is a primary care internist who is trained in epidemiology, biostatistics, and literature synthesis. Dr. Williams’ topical interests include depression, mental health services, dementia and implementation of best practices. He is a medical editor for the Patient Centered Outcomes Research Institute and the Evidence-base Practice Program. Dr. Williams is Senior Science Advisor to the Durham VA Evidence Synthesis Program and has led numerous systematic reviews, many focusing on mental health services. Dr. Williams is board certified in Internal Medicine and active in clinical practice and resident physician education at the Durham VAMC.

Education and Training

  • Fellow in General Internal Medicine, Medicine, University of Iowa, 1987 - 1988
  • Medical Resident, Medicine, University of Iowa, 1984 - 1987
  • M.D., University of North Carolina - Chapel Hill, 1984

Publications

Crowley, Matthew J., John W. Williams, Andrzej S. Kosinski, David A. D’Alessio, and John B. Buse. “Metformin Use May Moderate the Effect of DPP-4 Inhibitors on Cardiovascular Outcomes.” Diabetes Care 40, no. 12 (December 2017): 1787–89. https://doi.org/10.2337/dc17-1528.

PMID
29051159
Full Text

Nieuwsma, Jason A., John W. Williams, Natasha Namdari, Jeffrey B. Washam, Giselle Raitz, James A. Blumenthal, Wei Jiang, et al. “Diagnostic Accuracy of Screening Tests and Treatment for Post-Acute Coronary Syndrome Depression: A Systematic Review.” Ann Intern Med 167, no. 10 (November 21, 2017): 725–35. https://doi.org/10.7326/M17-1811.

PMID
29132152
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Shepherd-Banigan, M., K. M. Goldstein, R. R. Coeytaux, J. R. McDuffie, A. P. Goode, A. S. Kosinski, M. G. Van Noord, et al. “Improving vasomotor symptoms; psychological symptoms; and health-related quality of life in peri- or post-menopausal women through yoga: An umbrella systematic review and meta-analysis.” Complement Ther Med 34 (October 2017): 156–64. https://doi.org/10.1016/j.ctim.2017.08.011.

PMID
28917368
Full Text

El Husseini, Nada, Larry B. Goldstein, Eric D. Peterson, Xin Zhao, DaiWai M. Olson, John W. Williams, Cheryl Bushnell, and Daniel T. Laskowitz. “Depression Status Is Associated with Functional Decline Over 1-Year Following Acute Stroke.” J Stroke Cerebrovasc Dis 26, no. 7 (July 2017): 1393–99. https://doi.org/10.1016/j.jstrokecerebrovasdis.2017.03.026.

PMID
28389192
Full Text

Patel, Sachin, John W. Williams, and Robert B. Wallace. “What We Do (and Don't) Know About the Health Effects of Cannabis and Whether Marijuana Is Medicine.” Ann Intern Med 166, no. 10 (May 16, 2017): 747–48. https://doi.org/10.7326/M17-0501.

PMID
28384665
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Goldstein, K. M., M. Shepherd-Banigan, R. R. Coeytaux, J. R. McDuffie, S. Adam, D. Befus, A. P. Goode, A. S. Kosinski, V. Masilamani, and J. W. Williams. “Use of mindfulness, meditation and relaxation to treat vasomotor symptoms.” Climacteric 20, no. 2 (April 2017): 178–82. https://doi.org/10.1080/13697137.2017.1283685.

PMID
28286985
Full Text

Crowley, Matthew J., Clarissa J. Diamantidis, Jennifer R. McDuffie, C Blake Cameron, John W. Stanifer, Clare K. Mock, Xianwei Wang, et al. “Clinical Outcomes of Metformin Use in Populations With Chronic Kidney Disease, Congestive Heart Failure, or Chronic Liver Disease: A Systematic Review.” Ann Intern Med 166, no. 3 (February 7, 2017): 191–200. https://doi.org/10.7326/M16-1901.

PMID
28055049
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Goode, Adam P., Katherine S. Hall, Bryan C. Batch, Kim M. Huffman, S Nicole Hastings, Kelli D. Allen, Ryan J. Shaw, et al. “The Impact of Interventions that Integrate Accelerometers on Physical Activity and Weight Loss: A Systematic Review.” Ann Behav Med 51, no. 1 (February 2017): 79–93. https://doi.org/10.1007/s12160-016-9829-1.

PMID
27565168
Full Text

Duan-Porter, Wei, Karen M. Goldstein, Jennifer R. McDuffie, Jaime M. Hughes, Megan E. B. Clowse, Ruth S. Klap, Varsha Masilamani, et al. “Reporting of Sex Effects by Systematic Reviews on Interventions for Depression, Diabetes, and Chronic Pain.” Ann Intern Med 165, no. 3 (August 2, 2016): 184–93. https://doi.org/10.7326/M15-2877.

PMID
27111355
Full Text

Gayer, Christopher C., Matthew J. Crowley, William F. Lawrence, Jennifer M. Gierisch, Bridget Gaglio, John W. Williams, Evan R. Myers, Amy Kendrick, Jean Slutsky, and Gillian D. Sanders. “An overview and discussion of the Patient-Centered Outcomes Research Institute's decision aid portfolio.” J Comp Eff Res 5, no. 4 (July 2016): 407–15. https://doi.org/10.2217/cer-2016-0002.

PMID
27298206
Full Text

Pages