Jon Paul Gockerman, MD

Professor Emeritus of Medicine
Campus mail 25154 Morris Bldg, Durham, NC 27710
Phone (919) 684-8964
Email address gocke002@mc.duke.edu

My research effort is involved in clinical research studies through the CALGB as well as several sub interests. My interest is the use of 131I MIBG in the treatment of carcinoids. We have completed a dose seeking study to determine the maximum tolerated dose. This has been completed and this paper is in preparation for publication. We plan to do an additional study of randomization in patients with this agent to see if we can determine an objective response rate in a controlled group of patients.

The secondary issue is that of high dose chemotherapy in lymphoma. We have completed a study involving use of high dose chemotherapy in a transplant setting in patients with refractory lymphoma. This study has treated over 100 patients and is in the process of being written up.

Education and Training

  • M.D., The University of Chicago, 1967

Publications

Byrd, John C., Bercedis L. Peterson, Kanti R. Rai, David Hurd, Raymond Hohl, Michael C. Perry, Jon Gockerman, Sreenivasa Nattam, and Richard A. Larson. “Fludarabine followed by alemtuzumab consolidation for previously untreated chronic lymphocytic leukemia: final report of Cancer and Leukemia Group B study 19901.” Leuk Lymphoma 50, no. 10 (October 2009): 1589–96. https://doi.org/10.1080/10428190903150839.

PMID
19863336
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Rizzieri, David A., Jenny A. O’Brien, Gloria Broadwater, Carlos M. Decastro, Prakash Dev, Louis Diehl, Anne Beaven, et al. “Outcomes of patients who undergo aggressive induction therapy for secondary acute myeloid leukemia.” Cancer 115, no. 13 (July 1, 2009): 2922–29. https://doi.org/10.1002/cncr.24379.

PMID
19452542
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Castro, C. de, D. Adams, D. Rizzieri, J. Moore, J. Gockerman, L. Diehl, M. Horwitz, E. Edmonds, and J. Warzecho. “P134 A phase II pilot study of sorafenib in patients with myelodysplastic syndromes.” Leukemia Research 33, no. SUPPL. 1 (May 1, 2009). https://doi.org/10.1016/S0145-2126(09)70215-2.

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Castro, C. de, D. Adams, D. Rizzieri, J. Moore, J. Gockerman, L. Diehl, M. Horwitz, E. Edmonds, and J. Warzecho. “P129 A pilot study of decitabine in combination with arsenic trioxide for patients with myelodysplastic syndromes.” Leukemia Research 33, no. SUPPL. 1 (May 1, 2009). https://doi.org/10.1016/S0145-2126(09)70210-3.

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Lanasa, Mark C., Sallie D. Allgood, Karen M. Bond, Jon P. Gockerman, Marc C. Levesque, and J Brice Weinberg. “Oligoclonal TRBV gene usage among CD8(+) T cells in monoclonal B lymphocytosis and CLL.” Br J Haematol 145, no. 4 (May 2009): 535–37. https://doi.org/10.1111/j.1365-2141.2009.07635.x.

PMID
19298246
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Shea, Thomas C., Anne W. Beaven, Dominic T. Moore, Jonathan S. Serody, Don A. Gabriel, Nelson Chao, Jon P. Gockerman, Reynaldo A. Garcia, and David A. Rizzieri. “Sequential high-dose ifosfamide, carboplatin and etoposide with rituximab for relapsed Hodgkin and large B-cell non-Hodgkin lymphoma: increased toxicity without improvement in progression-free survival.” Leuk Lymphoma 50, no. 5 (May 2009): 741–48. https://doi.org/10.1080/10428190902853136.

PMID
19358012
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Weinberg, J. B., A. D. Volkheimer, M. Mihovilovic, N. Jiang, Y. Chen, K. Bond, J. O. Moore, et al. “Apolipoprotein E genotype as a determinant of survival in chronic lymphocytic leukemia.” Leukemia 22, no. 12 (December 2008): 2184–92. https://doi.org/10.1038/leu.2008.241.

PMID
18784741
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Ettinger, David S., Mark Agulnik, Mihaela Cristea, Keith Eaton, Panagiotis M. Fidias, Jon P. Gockerman, Omar Hameed, et al. “Occult primary.” J Natl Compr Canc Netw 6, no. 10 (November 2008): 1026–60. https://doi.org/10.6004/jnccn.2008.0078.

PMID
19176200
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Armstrong, Andrew J., Patricia Creel, James Turnbull, Cassandra Moore, Tracy A. Jaffe, Sherri Haley, William Petros, et al. “A phase I-II study of docetaxel and atrasentan in men with castration-resistant metastatic prostate cancer.” Clin Cancer Res 14, no. 19 (October 1, 2008): 6270–76. https://doi.org/10.1158/1078-0432.CCR-08-1085.

PMID
18829508
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Rao, Arati V., Islam R. Younis, Gregory J. Sand, Ivan Spasojevic, David J. Adams, Carlos M. Decastro, John P. Gockerman, et al. “Phase I evaluation of gemcitabine, mitoxantrone, and their effect on plasma disposition of fludarabine in patients with relapsed or refractory acute myeloid leukemia.” Leuk Lymphoma 49, no. 8 (August 2008): 1523–29. https://doi.org/10.1080/10428190802210700.

PMID
18766965
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