Jon Paul Gockerman, MD

Professor Emeritus of Medicine
Campus mail 25154 Morris Bldg, Durham, NC 27710
Phone (919) 684-8964
Email address gocke002@mc.duke.edu

My research effort is involved in clinical research studies through the CALGB as well as several sub interests. My interest is the use of 131I MIBG in the treatment of carcinoids. We have completed a dose seeking study to determine the maximum tolerated dose. This has been completed and this paper is in preparation for publication. We plan to do an additional study of randomization in patients with this agent to see if we can determine an objective response rate in a controlled group of patients.

The secondary issue is that of high dose chemotherapy in lymphoma. We have completed a study involving use of high dose chemotherapy in a transplant setting in patients with refractory lymphoma. This study has treated over 100 patients and is in the process of being written up.

Education and Training

  • M.D., The University of Chicago, 1967

Publications

Levesque, Marc C., Dipak K. Ghosh, Bethany E. Beasley, Youwei Chen, Alicia D. Volkheimer, Charles W. O’Loughlin, Jon P. Gockerman, Joseph O. Moore, and J Brice Weinberg. “CLL cell apoptosis induced by nitric oxide synthase inhibitors: correlation with lipid solubility and NOS1 dissociation constant.” Leuk Res 32, no. 7 (July 2008): 1061–70. https://doi.org/10.1016/j.leukres.2007.11.026.

PMID
18180035
Full Text

Zelenetz, Andrew D., Ranjana H. Advani, John C. Byrd, Myron S. Czuczman, Lloyd E. Damon, Madeleine Duvic, Luis Fayad, et al. “Non-Hodgkin's lymphomas.” J Natl Compr Canc Netw 6, no. 4 (April 2008): 356–421. https://doi.org/10.6004/jnccn.2008.0030.

PMID
18433606
Full Text

Sevilla, Deborah W., Jerald Z. Gong, Barbara K. Goodman, Patrick J. Buckley, Philip Rosoff, Jon P. Gockerman, and Anand S. Lagoo. “Clinicopathologic findings in high-grade B-cell lymphomas with typical Burkitt morphologic features but lacking the MYC translocation.” Am J Clin Pathol 128, no. 6 (December 2007): 981–91. https://doi.org/10.1309/C1PP15P7CDB8UY39.

PMID
18024324
Full Text

Weinberg, J Brice, Alicia D. Volkheimer, Youwei Chen, Bethany E. Beasley, Ning Jiang, Mark C. Lanasa, Daphne Friedman, et al. “Clinical and molecular predictors of disease severity and survival in chronic lymphocytic leukemia.” Am J Hematol 82, no. 12 (December 2007): 1063–70. https://doi.org/10.1002/ajh.20987.

PMID
17654680
Full Text

DeAngelo, Daniel J., Daohai Yu, Jeffrey L. Johnson, Steven E. Coutre, Richard M. Stone, Alison T. Stopeck, Jon P. Gockerman, Beverly S. Mitchell, Frederick R. Appelbaum, and Richard A. Larson. “Nelarabine induces complete remissions in adults with relapsed or refractory T-lineage acute lymphoblastic leukemia or lymphoblastic lymphoma: Cancer and Leukemia Group B study 19801.” Blood 109, no. 12 (June 15, 2007): 5136–42. https://doi.org/10.1182/blood-2006-11-056754.

PMID
17344466
Full Text

Peterson, Bruce A., Jeffrey Johnson, Margaret A. Shipp, Maurice Barcos, Jon P. Gockerman, George P. Canellos, and George P. Cancer and Leukemia Group B 9351. “High dose CHOP: a phase II study of initial treatment in aggressive non-Hodgkin lymphoma. Cancer and Leukemia Group B 9351.” Leuk Lymphoma 48, no. 5 (May 2007): 870–80. https://doi.org/10.1080/10428190701259758.

PMID
17487729
Full Text

Rizzieri, David A., Liang Piu Koh, Gwynn D. Long, Cristina Gasparetto, Keith M. Sullivan, Mitchell Horwitz, John Chute, et al. “Partially matched, nonmyeloablative allogeneic transplantation: clinical outcomes and immune reconstitution.” J Clin Oncol 25, no. 6 (February 20, 2007): 690–97. https://doi.org/10.1200/JCO.2006.07.0953.

PMID
17228020
Full Text

Volkheimer, Alicia D., J Brice Weinberg, Bethany E. Beasley, John F. Whitesides, Jon P. Gockerman, Joseph O. Moore, Garnett Kelsoe, Barbara K. Goodman, and Marc C. Levesque. “Progressive immunoglobulin gene mutations in chronic lymphocytic leukemia: evidence for antigen-driven intraclonal diversification.” Blood 109, no. 4 (February 15, 2007): 1559–67. https://doi.org/10.1182/blood-2006-05-020644.

PMID
17082314
Full Text

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