Jon Paul Gockerman, MD

Professor Emeritus of Medicine
Campus mail 25154 Morris Bldg, Durham, NC 27710
Phone (919) 684-8964
Email address gocke002@mc.duke.edu

My research effort is involved in clinical research studies through the CALGB as well as several sub interests. My interest is the use of 131I MIBG in the treatment of carcinoids. We have completed a dose seeking study to determine the maximum tolerated dose. This has been completed and this paper is in preparation for publication. We plan to do an additional study of randomization in patients with this agent to see if we can determine an objective response rate in a controlled group of patients.

The secondary issue is that of high dose chemotherapy in lymphoma. We have completed a study involving use of high dose chemotherapy in a transplant setting in patients with refractory lymphoma. This study has treated over 100 patients and is in the process of being written up.

Education and Training

  • M.D., The University of Chicago, 1967

Publications

Laughlin, M. J., D. S. McGaughey, J. R. Crews, N. J. Chao, D. Rizzieri, M. Ross, J. Gockerman, et al. “Secondary myelodysplasia and acute leukemia in breast cancer patients after autologous bone marrow transplant.” J Clin Oncol 16, no. 3 (March 1998): 1008–12. https://doi.org/10.1200/JCO.1998.16.3.1008.

PMID
9508184
Full Text

Shami, P. J., J. O. Moore, J. P. Gockerman, J. W. Hathorn, M. A. Misukonis, and J. B. Weinberg. “Nitric oxide modulation of the growth and differentiation of freshly isolated acute non-lymphocytic leukemia cells.” Leuk Res 19, no. 8 (August 1995): 527–33. https://doi.org/10.1016/0145-2126(95)00013-e.

PMID
7658698
Full Text

Brown, M. T., R. E. McClendon, and J. P. Gockerman. “Primary central nervous system lymphoma with systemic metastasis: case report and review.” J Neurooncol 23, no. 3 (1995): 207–21. https://doi.org/10.1007/BF01059952.

PMID
7673983
Full Text

Lachance, D. H., D. M. Brizel, J. P. Gockerman, E. C. Halperin, P. C. Burger, O. B. Boyko, M. T. Brown, and S. C. Schold. “Cyclophosphamide, doxorubicin, vincristine, and prednisone for primary central nervous system lymphoma: short-duration response and multifocal intracerebral recurrence preceding radiotherapy.” Neurology 44, no. 9 (September 1994): 1721–27. https://doi.org/10.1212/wnl.44.9.1721.

PMID
7936304
Full Text

Brizel, D. M., J. P. Gockerman, J. Crawford, J. W. Hathorn, J. O. Moore, B. Osborne, and L. R. Prosnitz. “A pilot study of etoposide, vinblastine, and doxorubicin plus involved field irradiation in advanced, previously untreated Hodgkin's disease.” Cancer 74, no. 1 (July 1, 1994): 159–63. https://doi.org/10.1002/1097-0142(19940701)74:1<159::aid-cncr2820740125>3.0.co;2-x.

PMID
8004571
Full Text

Glantz, M. J., H. Biran, M. E. Myers, J. P. Gockerman, and M. H. Friedberg. “The radiographic diagnosis and treatment of paraneoplastic central nervous system disease.” Cancer 73, no. 1 (January 1, 1994): 168–75. https://doi.org/10.1002/1097-0142(19940101)73:1<168::aid-cncr2820730129>3.0.co;2-z.

PMID
8275420
Full Text

Gockerman, J. P., E. C. Halperin, G. C. Magrinat, B. M. Hendrix, and W. P. Peters. “Physician-assisted suicide and advance directives concerning life support.” N C Med J 54, no. 7 (July 1993): 312–16.

PMID
8394511
Scholars@Duke

Ortel, T. L., J. P. Gockerman, R. M. Califf, R. L. McCann, C. M. O’Connor, D. M. Metzler, and C. S. Greenberg. “Parenteral anticoagulation with the heparinoid Lomoparan (Org 10172) in patients with heparin induced thrombocytopenia and thrombosis.” Thromb Haemost 67, no. 3 (March 2, 1992): 292–96.

PMID
1379384
Scholars@Duke

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