Jonathan Solomon Stamler, MD

Adjunct Professor in the Department of Medicine
Campus mail 321 MSRB, Durham, NC 27710
Phone (919) 684-6933
Email address staml001@mc.duke.edu

Biochemistry of nitric oxide and related nitro (so)-compounds
Biochemistry and metabolic functions of biological sulfhydryls
Free radical mechanisms in biology

Education and Training

  • M.D., Icahn School of Medicine at Mount Sinai, 1985

Publications

Stomberski, CT, Hess, DT, and Stamler, JS. "Protein S-Nitrosylation: Determinants of Specificity and Enzymatic Regulation of S-Nitrosothiol-Based Signaling." Antioxidants & Redox Signaling 30, no. 10 (April 2019): 1331-1351.

PMID
29130312
Full Text

Seth, P, Hsieh, PN, Jamal, S, Wang, L, Gygi, SP, Jain, MK, Coller, J, and Stamler, JS. "Regulation of MicroRNA Machinery and Development by Interspecies S-Nitrosylation." Cell 176, no. 5 (February 2019): 1014-1025.e12.

PMID
30794773
Full Text

Stomberski, CT, Zhou, H-L, Wang, L, van den Akker, F, and Stamler, JS. "Molecular recognition of S-nitrosothiol substrate by its cognate protein denitrosylase." The Journal of Biological Chemistry 294, no. 5 (February 2019): 1568-1578.

PMID
30538128
Full Text

Zhou, H-L, Zhang, R, Anand, P, Stomberski, CT, Qian, Z, Hausladen, A, Wang, L, Rhee, EP, Parikh, SM, Karumanchi, SA, and Stamler, JS. "Metabolic reprogramming by the S-nitroso-CoA reductase system protects against kidney injury." Nature 565, no. 7737 (January 2019): 96-100.

PMID
30487609
Full Text

Reynolds, JD, Jenkins, T, Matto, F, Nazemian, R, Farhan, O, Morris, N, Longphre, JM, Hess, DT, Moon, RE, Piantadosi, CA, and Stamler, JS. "Pharmacologic Targeting of Red Blood Cells to Improve Tissue Oxygenation." Clinical Pharmacology and Therapeutics 104, no. 3 (September 2018): 553-563.

PMID
29238951
Full Text

Zhou, HL, Stomberski, CT, and Stamler, JS. "Cross Talk between S-Nitrosylation and Phosphorylation Involving Kinases and Nitrosylases." Circulation Research 122, no. 11 (May 25, 2018): 1485-1487. (Review)

Full Text

Hayashi, H, Hess, DT, Zhang, R, Sugi, K, Gao, H, Tan, BL, Bowles, DE, Milano, CA, Jain, MK, Koch, WJ, and Stamler, JS. "S-Nitrosylation of β-Arrestins Biases Receptor Signaling and Confers Ligand Independence." Molecular Cell 70, no. 3 (May 2018): 473-487.e6.

PMID
29727618
Full Text

Liao, X, Shen, Y, Zhang, R, Sugi, K, Vasudevan, NT, Alaiti, MA, Sweet, DR, Zhou, L, Qing, Y, Gerson, SL, Fu, C, Wynshaw-Boris, A, Hu, R, Schwartz, MA, Fujioka, H, Richardson, B, Cameron, MJ, Hayashi, H, Stamler, JS, and Jain, MK. "Distinct roles of resident and nonresident macrophages in nonischemic cardiomyopathy." Proceedings of the National Academy of Sciences of the United States of America 115, no. 20 (May 2018): E4661-E4669.

PMID
29712858
Full Text

Rizza, S, Cardaci, S, Montagna, C, Di Giacomo, G, De Zio, D, Bordi, M, Maiani, E, Campello, S, Borreca, A, Puca, AA, Stamler, JS, Cecconi, F, and Filomeni, G. "S-nitrosylation drives cell senescence and aging in mammals by controlling mitochondrial dynamics and mitophagy." Proceedings of the National Academy of Sciences of the United States of America 115, no. 15 (April 2018): E3388-E3397.

PMID
29581312
Full Text

Matto, F, Kouretas, PC, Smith, R, Ostrowsky, J, Cina, AJ, Hess, DT, Stamler, JS, and Reynolds, JD. "S-Nitrosohemoglobin Levels and Patient Outcome After Transfusion During Pediatric Bypass Surgery." Clinical and Translational Science 11, no. 2 (March 2018): 237-243.

PMID
29232772
Full Text

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