Julia Jarrard Scialla, MD

Associate Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail 2400 Pratt Street, Rm 7042, Durham, NC 27705
Phone (919) 668-8764
Email address julia.scialla@duke.edu

Dr. Scialla is an Associate Professor of Medicine in Nephrology at Duke University and a faculty member at the Duke Clinical Research Institute.  Dr. Scialla trained in Internal Medicine, Nephrology, and Clinical Epidemiology at the Johns Hopkins University School of Medicine and the Johns Hopkins Bloomberg School of Public Health.  Her research focuses on chronic kidney disease (CKD) epidemiology and prevention, with an emphasis on the role of metabolic complications and nutrition. Current studies are focused on treatment and prevention of abnormal phosphate homeostasis, acid-base physiology, diabetic and other forms of kidney disease, and outcomes in end-stage kidney disease. 

Dr. Scialla’s work engages a number of study designs including prospective cohort studies, observational comparative effectiveness studies, and patient-oriented physiologic studies. She has worked closely with multiple chronic disease cohorts including the Chronic Renal Insufficiency Cohort (CRIC) Study, the African American Study of Kidney Disease and Hypertension (AASK), the Jackson Heart Study (JHS), and secondary analyses in clinical trials. Studies in electronic health records (EHR) and registries have engaged dialysis EHR data, the United States Renal Data System, and public registries, such as the National Health and Nutrition Examination Survey. Physiologic studies include the Acid Base Complication in CKD Study, secondary analyses in the DASH Mechanism Study, and the newly launched MURDOCK Kidney Health Study.

Education and Training

  • Nephrology, Fellowship, Johns Hopkins University School of Medicine, 2006 - 2010
  • Residency, Internal Medicine, Johns Hopkins University School of Medicine, 2003 - 2006
  • M.H.S., Johns Hopkins Bloomberg School of Public Health, 2010
  • M.D., University of Pennsylvania, 2003

Publications

Isakova, T, Craven, TE, Scialla, JJ, Nickolas, TL, Schnall, A, Barzilay, J, Schwartz, AV, and Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial, . "Change in estimated glomerular filtration rate and fracture risk in the Action to Control Cardiovascular Risk in Diabetes Trial." Bone 78 (September 2015): 23-27.

PMID
25937184
Full Text

Scialla, JJ, and Wolf, M. "When there will never be a randomized controlled trial." Kidney International 88, no. 2 (August 2015): 220-222.

PMID
26230199
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Scialla, JJ. "The balance of the evidence on acid-base homeostasis and progression of chronic kidney disease." Kidney international 88, no. 1 (July 2015): 9-11.

PMID
26126088
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Scialla, JJ. "Epidemiologic insights on the role of fibroblast growth factor 23 in cardiovascular disease." Current Opinion in Nephrology and Hypertension 24, no. 3 (May 2015): 260-267. (Review)

PMID
26066475
Full Text

Dobre, M, Yang, W, Pan, Q, Appel, L, Bellovich, K, Chen, J, Feldman, H, Fischer, MJ, Ham, LL, Hostetter, T, Jaar, BG, Kallem, RR, Rosas, SE, Scialla, JJ, Wolf, M, Rahman, M, and CRIC Study Investigators, . "Persistent high serum bicarbonate and the risk of heart failure in patients with chronic kidney disease (CKD): A report from the Chronic Renal Insufficiency Cohort (CRIC) study." Journal of the American Heart Association 4, no. 4 (April 20, 2015).

PMID
25896890
Full Text

Tangri, N, Miskulin, DC, Zhou, J, Bandeen-Roche, K, Michels, WM, Ephraim, PL, McDermott, A, Crews, DC, Scialla, JJ, Sozio, SM, Shafi, T, Jaar, BG, Meyer, K, Boulware, LE, and DEcIDE Network Patient Outcomes in End-Stage Renal Disease Study Investigators, . "Effect of intravenous iron use on hospitalizations in patients undergoing hemodialysis: a comparative effectiveness analysis from the DEcIDE-ESRD study." Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association European Renal Association 30, no. 4 (April 2015): 667-675.

PMID
25366328
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Isakova, T, Craven, TE, Lee, J, Scialla, JJ, Xie, H, Wahl, P, Marcovina, SM, Byington, RP, and Wolf, M. "Fibroblast growth factor 23 and incident CKD in type 2 diabetes." Clinical Journal of the American Society of Nephrology : Cjasn 10, no. 1 (January 2015): 29-38.

PMID
25343949
Full Text

Scialla, JJ, Parekh, RS, Eustace, JA, Astor, BC, Plantinga, L, Jaar, BG, Shafi, T, Coresh, J, Powe, NR, and Melamed, ML. "Race, Mineral Homeostasis and Mortality in Patients with End-Stage Renal Disease on Dialysis." American journal of nephrology 42, no. 1 (January 2015): 25-34.

PMID
26287973
Full Text

Miskulin, DC, Tangri, N, Bandeen-Roche, K, Zhou, J, McDermott, A, Meyer, KB, Ephraim, PL, Michels, WM, Jaar, BG, Crews, DC, Scialla, JJ, Sozio, SM, Shafi, T, Wu, AW, Cook, C, Boulware, LE, and Developing Evidence to Inform Decisions about Effectiveness (DEcIDE) Network Patient Outcomes in End Stage Renal Disease Study Investigators, . "Intravenous iron exposure and mortality in patients on hemodialysis." Clinical Journal of the American Society of Nephrology : Cjasn 9, no. 11 (November 2014): 1930-1939.

PMID
25318751
Full Text

Scialla, JJ, Liu, J, Crews, DC, Guo, H, Bandeen-Roche, K, Ephraim, PL, Tangri, N, Sozio, SM, Shafi, T, Miskulin, DC, Michels, WM, Jaar, BG, Wu, AW, Powe, NR, Boulware, LE, and DEcIDE Network Patient Outcomes in End Stage Renal Disease Study Investigators, . "An instrumental variable approach finds no associated harm or benefit with early dialysis initiation in the United States." Kidney International 86, no. 4 (October 2014): 798-809.

PMID
24786707
Full Text

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