Julia Jarrard Scialla, MD

Adjunct Associate Professor in the Department of Medicine
Member in the Duke Clinical Research Institute
Campus mail 2400 Pratt Street, Rm 7042, Durham, NC 27705
Phone (919) 668-8764
Email address julia.scialla@duke.edu

Dr. Scialla is an Associate Professor of Medicine in Nephrology at Duke University and a faculty member at the Duke Clinical Research Institute.  Dr. Scialla trained in Internal Medicine, Nephrology, and Clinical Epidemiology at the Johns Hopkins University School of Medicine and the Johns Hopkins Bloomberg School of Public Health.  Her research focuses on chronic kidney disease (CKD) epidemiology and prevention, with an emphasis on the role of metabolic complications and nutrition. Current studies are focused on treatment and prevention of abnormal phosphate homeostasis, acid-base physiology, diabetic and other forms of kidney disease, and outcomes in end-stage kidney disease. 

Dr. Scialla’s work engages a number of study designs including prospective cohort studies, observational comparative effectiveness studies, and patient-oriented physiologic studies. She has worked closely with multiple chronic disease cohorts including the Chronic Renal Insufficiency Cohort (CRIC) Study, the African American Study of Kidney Disease and Hypertension (AASK), the Jackson Heart Study (JHS), and secondary analyses in clinical trials. Studies in electronic health records (EHR) and registries have engaged dialysis EHR data, the United States Renal Data System, and public registries, such as the National Health and Nutrition Examination Survey. Physiologic studies include the Acid Base Complication in CKD Study, secondary analyses in the DASH Mechanism Study, and the newly launched MURDOCK Kidney Health Study.

Education and Training

  • Nephrology, Fellowship, Johns Hopkins University School of Medicine, 2006 - 2010
  • Residency, Internal Medicine, Johns Hopkins University School of Medicine, 2003 - 2006
  • M.H.S., Johns Hopkins Bloomberg School of Public Health, 2010
  • M.D., University of Pennsylvania, 2003

Publications

Boulware, L Ebony, Navdeep Tangri, Patti L. Ephraim, Julia J. Scialla, Stephen M. Sozio, Deidra C. Crews, Tariq Shafi, et al. “Comparative effectiveness studies to improve clinical outcomes in end stage renal disease: the DEcIDE patient outcomes in end stage renal disease study..” Bmc Nephrol 13 (December 6, 2012). https://doi.org/10.1186/1471-2369-13-167.

PMID
23217181
Full Text

Scialla, Julia J., Lawrence J. Appel, Myles Wolf, Wei Yang, Xiaoming Zhang, Stephen M. Sozio, Edgar R. Miller, et al. “Plant protein intake is associated with fibroblast growth factor 23 and serum bicarbonate levels in patients with chronic kidney disease: the Chronic Renal Insufficiency Cohort study..” J Ren Nutr 22, no. 4 (July 2012): 379-388.e1. https://doi.org/10.1053/j.jrn.2012.01.026.

PMID
22480598
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Scialla, Julia J., Lawrence J. Appel, Brad C. Astor, Edgar R. Miller, Srinivasan Beddhu, Mark Woodward, Rulan S. Parekh, Cheryl A. M. Anderson, and Cheryl A. M. African American Study of Kidney Disease and Hypertension Study Group. “Net endogenous acid production is associated with a faster decline in GFR in African Americans..” Kidney Int 82, no. 1 (July 2012): 106–12. https://doi.org/10.1038/ki.2012.82.

PMID
22475819
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Wahl, Patricia, Huiliang Xie, Julia Scialla, Cheryl A. M. Anderson, Keith Bellovich, Carolyn Brecklin, Jing Chen, et al. “Earlier onset and greater severity of disordered mineral metabolism in diabetic patients with chronic kidney disease..” Diabetes Care 35, no. 5 (May 2012): 994–1001. https://doi.org/10.2337/dc11-2235.

PMID
22446176
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Faul, Christian, Ansel P. Amaral, Behzad Oskouei, Ming-Chang Hu, Alexis Sloan, Tamara Isakova, Orlando M. Gutiérrez, et al. “FGF23 induces left ventricular hypertrophy..” J Clin Invest 121, no. 11 (November 2011): 4393–4408. https://doi.org/10.1172/JCI46122.

PMID
21985788
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Scialla, Julia J., Mary B. Leonard, Raymond R. Townsend, Lawrence Appel, Myles Wolf, Matt J. Budoff, Jing Chen, et al. “Correlates of osteoprotegerin and association with aortic pulse wave velocity in patients with chronic kidney disease..” Clin J Am Soc Nephrol 6, no. 11 (November 2011): 2612–19. https://doi.org/10.2215/CJN.03910411.

PMID
21940840
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Scialla, Julia J., Lawrence J. Appel, Brad C. Astor, Edgar R. Miller, Srinivasan Beddhu, Mark Woodward, Rulan S. Parekh, and Cheryl A. M. Anderson. “Estimated net endogenous acid production and serum bicarbonate in African Americans with chronic kidney disease..” Clin J Am Soc Nephrol 6, no. 7 (July 2011): 1526–32. https://doi.org/10.2215/CJN.00150111.

PMID
21700817
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Isakova, Tamara, Huiliang Xie, Wei Yang, Dawei Xie, Amanda Hyre Anderson, Julia Scialla, Patricia Wahl, et al. “Fibroblast growth factor 23 and risks of mortality and end-stage renal disease in patients with chronic kidney disease..” Jama 305, no. 23 (June 15, 2011): 2432–39. https://doi.org/10.1001/jama.2011.826.

PMID
21673295
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Isakova, Tamara, Patricia Wahl, Gabriela S. Vargas, Orlando M. Gutiérrez, Julia Scialla, Huiliang Xie, Dina Appleby, et al. “Fibroblast growth factor 23 is elevated before parathyroid hormone and phosphate in chronic kidney disease..” Kidney Int 79, no. 12 (June 2011): 1370–78. https://doi.org/10.1038/ki.2011.47.

PMID
21389978
Full Text

Scialla, Julia J., Laura C. Plantinga, WH Linda Kao, Bernard Jaar, Neil R. Powe, and Rulan S. Parekh. “Soluble P-selectin levels are associated with cardiovascular mortality and sudden cardiac death in male dialysis patients..” Am J Nephrol 33, no. 3 (2011): 224–30. https://doi.org/10.1159/000324517.

PMID
21346329
Full Text

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