Kathleen Anne Welsh-Bohmer, PhD

Professor of Psychiatry and Behavioral Sciences
Director, of Alzheimer's Disease Research Center
Professor in Neurology
Faculty Network Member of the Duke Institute for Brain Sciences
Member in the Duke Clinical Research Institute
Campus mail 2200 W Main St Ste A200, Durham, NC 27705
Phone (919) 668-0820
Email address kathleen.welshbohmer@duke.edu

Dr. Kathleen Welsh-Bohmer is a Professor of Psychiatry with a secondary appointment in the Department of Neurology. She is also the Chief of the Medical Psychology CPU, the professional home for the over 200 academic psychologists within Duke Medical Center.  

Clinically trained as a neuropsychologist, Dr. Welsh-Bohmer's research activities have been focused around developing effective prevention and treatment strategies to delay the onset of cognitive disorders occurring in later life.  Since 2006 she has directed the Joseph and Kathleen Bryan Alzheimer’s Center in the Department of Neurology, where she leads a large multidisciplinary team focused on discovering the biological basis of Alzheimer’s disease and developing methods to enhance early diagnosis and speed drug discovery.

Currently, she oversees the neuropsychology scientific operations of a Phase III global clinical trial to delay the onset of Alzheimer’s disease entitled the “TOMMORROW” study (Takeda Pharmaceutical Company funded). The methods her team is developing for this study fill an information void and have implications for accelerating global clinical trials in Alzheimer’s disease prevention.

Education and Training

  • Ph.D., University of Virginia, 1985

Publications

Klinger, Rebecca Y., Mary Cooter, Tiffany Bisanar, Niccolò Terrando, Miles Berger, Mihai V. Podgoreanu, Mark Stafford-Smith, Mark F. Newman, Joseph P. Mathew, and Joseph P. Neurologic Outcomes Research Group of the Duke Heart Center. “Intravenous Lidocaine Does Not Improve Neurologic Outcomes after Cardiac Surgery: A Randomized Controlled Trial..” Anesthesiology 130, no. 6 (June 2019): 958–70. https://doi.org/10.1097/ALN.0000000000002668.

PMID
30870159
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Blumenthal, James A., Patrick J. Smith, Stephanie Mabe, Alan Hinderliter, Pao-Hwa Lin, Lawrence Liao, Kathleen A. Welsh-Bohmer, et al. “Lifestyle and neurocognition in older adults with cognitive impairments: A randomized trial..” Neurology 92, no. 3 (January 15, 2019): e212–23. https://doi.org/10.1212/WNL.0000000000006784.

PMID
30568005
Full Text

Knodt, A. R., J. R. Burke, K. A. Welsh-Bohmer, B. L. Plassman, D. K. Burns, S. K. Brannan, M. Kukulka, J. Wu, and A. R. Hariri. “Effects of pioglitazone on mnemonic hippocampal function: A blood oxygen level–dependent functional magnetic resonance imaging study in elderly adults.” Alzheimer’S and Dementia: Translational Research and Clinical Interventions 5 (January 1, 2019): 254–63. https://doi.org/10.1016/j.trci.2019.05.004.

Full Text

Tsui-Caldwell, Y. H. W., T. J. Farrer, Z. McDonnell, Z. Christensen, C. Finuf, E. D. Bigler, J. T. Tschanz, M. C. Norton, and K. A. Welsh-Bohmer. “MRI Clinical Ratings and Cognitive Function in a Cross-Sectional Population Study of Dementia: The Cache County Memory Study..” J Prev Alzheimers Dis 6, no. 2 (2019): 100–107. https://doi.org/10.14283/jpad.2019.1.

PMID
30756116
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Deming, Yuetiva, Logan Dumitrescu, Lisa L. Barnes, Madhav Thambisetty, Brian Kunkle, Katherine A. Gifford, William S. Bush, et al. “Sex-specific genetic predictors of Alzheimer's disease biomarkers..” Acta Neuropathol 136, no. 6 (December 2018): 857–72. https://doi.org/10.1007/s00401-018-1881-4.

PMID
29967939
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Hohman, Timothy J., Logan Dumitrescu, Lisa L. Barnes, Madhav Thambisetty, Gary Beecham, Brian Kunkle, Katherine A. Gifford, et al. “Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau..” Jama Neurol 75, no. 8 (August 1, 2018): 989–98. https://doi.org/10.1001/jamaneurol.2018.0821.

PMID
29801024
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Browndyke, Jeffrey N., Miles Berger, Patrick J. Smith, Todd B. Harshbarger, Zachary A. Monge, Viral Panchal, Tiffany L. Bisanar, et al. “Task-related changes in degree centrality and local coherence of the posterior cingulate cortex after major cardiac surgery in older adults..” Hum Brain Mapp 39, no. 2 (February 2018): 985–1003. https://doi.org/10.1002/hbm.23898.

PMID
29164774
Full Text

Morrison, Randall L., Huiling Pei, Gerald Novak, Daniel I. Kaufer, Kathleen A. Welsh-Bohmer, Stephen Ruhmel, and Vaibhav A. Narayan. “A computerized, self-administered test of verbal episodic memory in elderly patients with mild cognitive impairment and healthy participants: A randomized, crossover, validation study..” Alzheimers Dement (Amst) 10 (2018): 647–56. https://doi.org/10.1016/j.dadm.2018.08.010.

PMID
30456291
Full Text

Peloso, G. M., S. J. van der Lee, R. Sims, A. C. Naj, C. Bellenguez, N. Badarinarayan, J. Jakobsdottir, et al. “Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease.” Alzheimer’S and Dementia: Diagnosis, Assessment and Disease Monitoring 10 (January 1, 2018): 595–98. https://doi.org/10.1016/j.dadm.2018.08.008.

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Weintraub, Sandra, Lilah Besser, Hiroko H. Dodge, Merilee Teylan, Steven Ferris, Felicia C. Goldstein, Bruno Giordani, et al. “Version 3 of the Alzheimer Disease Centers' Neuropsychological Test Battery in the Uniform Data Set (UDS)..” Alzheimer Dis Assoc Disord 32, no. 1 (January 2018): 10–17. https://doi.org/10.1097/WAD.0000000000000223.

PMID
29240561
Full Text

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